ATE367828T1 - Igf-enthaltende injizierbare formulierungen enthaltend succinate als puffermittel - Google Patents
Igf-enthaltende injizierbare formulierungen enthaltend succinate als puffermittelInfo
- Publication number
- ATE367828T1 ATE367828T1 AT99916414T AT99916414T ATE367828T1 AT E367828 T1 ATE367828 T1 AT E367828T1 AT 99916414 T AT99916414 T AT 99916414T AT 99916414 T AT99916414 T AT 99916414T AT E367828 T1 ATE367828 T1 AT E367828T1
- Authority
- AT
- Austria
- Prior art keywords
- igf
- injectable formulations
- buffering agent
- succinate
- active agent
- Prior art date
Links
- 239000007972 injectable composition Substances 0.000 title abstract 2
- 239000006172 buffering agent Substances 0.000 title 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 3
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 2
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000000872 buffer Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8000898P | 1998-04-03 | 1998-04-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE367828T1 true ATE367828T1 (de) | 2007-08-15 |
Family
ID=22154445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99916414T ATE367828T1 (de) | 1998-04-03 | 1999-04-02 | Igf-enthaltende injizierbare formulierungen enthaltend succinate als puffermittel |
Country Status (10)
Country | Link |
---|---|
US (1) | US20070249522A1 (de) |
EP (1) | EP1069912B1 (de) |
JP (1) | JP2002510653A (de) |
AT (1) | ATE367828T1 (de) |
AU (1) | AU3473999A (de) |
DE (1) | DE69936638T2 (de) |
DK (1) | DK1069912T3 (de) |
ES (1) | ES2288018T3 (de) |
PT (1) | PT1069912E (de) |
WO (1) | WO1999051272A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2386228A1 (en) | 1999-10-04 | 2001-04-12 | Chiron Corporation | Stabilized liquid pharmaceutical compositions comprising tissue factor pathway inhibitor (tfpi) polypeptides |
US6887462B2 (en) | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
JP3993560B2 (ja) | 2001-08-30 | 2007-10-17 | ステム セル セラピューティクス インコーポレイテッド | 神経幹細胞の分化およびその治療用途 |
US7393830B2 (en) | 2001-09-14 | 2008-07-01 | Stem Cell Therapeutics Inc. | Prolactin induced increase in neural stem cell numbers |
AR036402A1 (es) * | 2001-09-18 | 2004-09-08 | Stem Cell Therapeutics Inc | Efecto de la hormona de crecimiento y de igf-1 sobre celulas madre neuronales. |
EP1546198A1 (de) | 2002-07-31 | 2005-06-29 | Stem Cell Therapeutics Inc. | Verfahren zur verbesserung der proliferation, der differenzierung und des berlebens von neuralen stammzellen unter verwendung von pituitary adenylate cyclase activating polypeptide (pacap) |
DE602004019761D1 (de) | 2003-01-08 | 2009-04-16 | Novartis Vaccines & Diagnostic | Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante |
CA2664629A1 (en) | 2005-09-27 | 2007-04-05 | Christopher Gregg | Oligodendrocyte precursor cell proliferation regulated by prolactin |
TWI705820B (zh) * | 2018-06-22 | 2020-10-01 | 美商美國禮來大藥廠 | Gip/glp1促效劑組合物 |
US11097023B1 (en) * | 2020-07-02 | 2021-08-24 | Par Pharmaceutical, Inc. | Pre-filled syringe containing sugammadex |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3273597D1 (en) * | 1981-11-28 | 1986-11-06 | Sunstar Kk | Pharmaceutical composition containing interferon in stable state |
JPS6069037A (ja) * | 1983-09-26 | 1985-04-19 | Sunstar Inc | エリテマト−デス治療用外用剤 |
US4605555A (en) * | 1984-09-20 | 1986-08-12 | Sun Star Kabushiki Kaisha | Composition and method for treating keratosic disorder of skin and mucosa |
EP0284249A1 (de) * | 1987-03-13 | 1988-09-28 | Interferon Sciences, Inc. | Gefriergetrocknete Lymphokin-Zusammensetzung |
US5151265A (en) * | 1987-11-03 | 1992-09-29 | Genentech, Inc. | Gamma interferon formulation |
EP0326151B1 (de) * | 1988-01-29 | 1993-06-16 | Sumitomo Pharmaceuticals Company, Limited | Verbesserte Formulierungen mit kontrollierter Abgabe |
US5374620A (en) * | 1990-06-07 | 1994-12-20 | Genentech, Inc. | Growth-promoting composition and its use |
US5126324A (en) * | 1990-06-07 | 1992-06-30 | Genentech, Inc. | Method of enhancing growth in patients using combination therapy |
US5681814A (en) * | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
JP3698721B2 (ja) * | 1993-02-23 | 2005-09-21 | ジェネンテク・インコーポレイテッド | 有機溶媒を用いて処理したポリペプチドの賦形剤安定化 |
IT1272252B (it) * | 1994-05-16 | 1997-06-16 | Applied Research Systems | Formulazioni liquide di interferone beta |
TW426523B (en) * | 1995-04-06 | 2001-03-21 | Hoffmann La Roche | Interferon solution |
US6511811B1 (en) * | 1995-06-07 | 2003-01-28 | The Regents Of The University Of California | Protein kinase C antagonist related to insulin receptor |
US5977057A (en) * | 1996-05-08 | 1999-11-02 | The University Of Vermont And State Agricultural College | Thrombosis prophylaxis for factor VLEIDEN carriers |
US5783556A (en) * | 1996-08-13 | 1998-07-21 | Genentech, Inc. | Formulated insulin-containing composition |
DE19825736C2 (de) * | 1997-06-11 | 2003-09-18 | Hyundai Electronics Ind | Verfahren zum Bilden eines Kondensators einer Halbleitervorrichtung |
US6663899B2 (en) * | 1997-06-13 | 2003-12-16 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
US6887462B2 (en) * | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
-
1999
- 1999-04-02 EP EP99916414A patent/EP1069912B1/de not_active Expired - Lifetime
- 1999-04-02 AT AT99916414T patent/ATE367828T1/de not_active IP Right Cessation
- 1999-04-02 DK DK99916414T patent/DK1069912T3/da active
- 1999-04-02 PT PT99916414T patent/PT1069912E/pt unknown
- 1999-04-02 JP JP2000542042A patent/JP2002510653A/ja active Pending
- 1999-04-02 ES ES99916414T patent/ES2288018T3/es not_active Expired - Lifetime
- 1999-04-02 WO PCT/US1999/007531 patent/WO1999051272A1/en active IP Right Grant
- 1999-04-02 DE DE69936638T patent/DE69936638T2/de not_active Expired - Fee Related
- 1999-04-02 AU AU34739/99A patent/AU3473999A/en not_active Abandoned
-
2007
- 2007-07-03 US US11/773,184 patent/US20070249522A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU3473999A (en) | 1999-10-25 |
DE69936638D1 (de) | 2007-09-06 |
DE69936638T2 (de) | 2008-05-21 |
ES2288018T3 (es) | 2007-12-16 |
EP1069912B1 (de) | 2007-07-25 |
JP2002510653A (ja) | 2002-04-09 |
WO1999051272A1 (en) | 1999-10-14 |
US20070249522A1 (en) | 2007-10-25 |
PT1069912E (pt) | 2007-09-14 |
EP1069912A1 (de) | 2001-01-24 |
DK1069912T3 (da) | 2007-11-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU7328601A (en) | Skin care compositions containing silicone elastomers | |
AU7315301A (en) | Compounds and compositions for delivering active agents | |
EA200000629A1 (ru) | Стабилизированные растворы терипаратида | |
TW200626613A (en) | Analogues of GLP-1 | |
IL140930A0 (en) | Compounds and compositions for delivering active agents | |
EA200300026A1 (ru) | Аналоги глюкагоноподобного пептида-1 | |
MXPA01008611A (es) | Compuestos y composiciones para suministrar agentes activos. | |
MY121684A (en) | Non-aqueous protic peptide formulations | |
HK1036970A1 (en) | Compounds and compositions for delivering active agents. | |
MY128850A (en) | Non-aqueous polar aprotic peptide formulations | |
EP1015008A4 (de) | Verbindungen und zusammensetzungen zur administration aktiver stoffe | |
RS105704A (sr) | Kiseli preparati insulina sa poboljšanom stabilnošću | |
MY125556A (en) | Aqueous formulations of peptide | |
AU2274201A (en) | Compounds and compositions for delivering active agents | |
ATE311373T1 (de) | Oxadiazolverbindungen und -zusammensetzungen zur abgabe von wirkstoffen | |
DE69417252T2 (de) | Verbesserte immunogene zusammensetzung gegen mensliches gastrin 17 | |
ATE367828T1 (de) | Igf-enthaltende injizierbare formulierungen enthaltend succinate als puffermittel | |
AU2001296865A1 (en) | (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents | |
NO20045507L (no) | Injiserbare faste hyaluronsyrebaerere for levering av osteogene proteiner | |
RS50046B (sr) | Farmaceutske kompozicije tizoksanida i nitazoksanida | |
MY131488A (en) | Low dose liquid entecavir formulations and use | |
DE60003943D1 (de) | Trimegestone enthaltende pharmazeutische zusammensetzungen | |
EA199901116A1 (ru) | Композиция, включающая 5-[4-[2-(n-метил-n-2-пиридил)-амино)этокси]бензил]тиазолидин-2,4-дион | |
WO2002024181A3 (en) | The use of melatonin for induction of general anesthesia | |
AU1351302A (en) | Inhibition or reversal of skin aging by actin-sequestering peptides |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1069912 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |