DK1069912T3 - Injicerbare IGF-formuleringer, der indeholder succinat som puffermiddel - Google Patents

Injicerbare IGF-formuleringer, der indeholder succinat som puffermiddel

Info

Publication number
DK1069912T3
DK1069912T3 DK99916414T DK99916414T DK1069912T3 DK 1069912 T3 DK1069912 T3 DK 1069912T3 DK 99916414 T DK99916414 T DK 99916414T DK 99916414 T DK99916414 T DK 99916414T DK 1069912 T3 DK1069912 T3 DK 1069912T3
Authority
DK
Denmark
Prior art keywords
igf
injectable
buffer
formulations containing
formulations
Prior art date
Application number
DK99916414T
Other languages
Danish (da)
English (en)
Inventor
Bret Shirley
Maninder S Hora
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of DK1069912T3 publication Critical patent/DK1069912T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK99916414T 1998-04-03 1999-04-02 Injicerbare IGF-formuleringer, der indeholder succinat som puffermiddel DK1069912T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8000898P 1998-04-03 1998-04-03
PCT/US1999/007531 WO1999051272A1 (en) 1998-04-03 1999-04-02 Injectable igf-formulations containing succinate as buffering agent

Publications (1)

Publication Number Publication Date
DK1069912T3 true DK1069912T3 (da) 2007-11-12

Family

ID=22154445

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99916414T DK1069912T3 (da) 1998-04-03 1999-04-02 Injicerbare IGF-formuleringer, der indeholder succinat som puffermiddel

Country Status (10)

Country Link
US (1) US20070249522A1 (de)
EP (1) EP1069912B1 (de)
JP (1) JP2002510653A (de)
AT (1) ATE367828T1 (de)
AU (1) AU3473999A (de)
DE (1) DE69936638T2 (de)
DK (1) DK1069912T3 (de)
ES (1) ES2288018T3 (de)
PT (1) PT1069912E (de)
WO (1) WO1999051272A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1491208E (pt) 1999-10-04 2010-05-12 Novartis Vaccines & Diagnostic Composições farmacêuticas contendo polipéptido líquidas estabilizadas
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
EP1423509A2 (de) 2001-08-30 2004-06-02 Stem Cell Therapeutics Inc. Differenzierung von neuralen stammzellen und therapeutische anwendung
EP1430114B1 (de) 2001-09-14 2012-01-18 Stem Cell Therapeutics Inc. Prolaktin-induzierte zunahme an neuronalen stammzellen und dessen therapeutische anwendung
AR036402A1 (es) * 2001-09-18 2004-09-08 Stem Cell Therapeutics Inc Efecto de la hormona de crecimiento y de igf-1 sobre celulas madre neuronales.
AU2003250705A1 (en) 2002-07-31 2004-02-16 Stem Cell Therapeutics Inc. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
SI1599222T1 (sl) 2003-01-08 2009-08-31 Novartis Vaccines & Diagnostic Stabilizirani vodni sestavki, ki obsegajo inhibitor poti tkivnega faktorja (TFPI) ali varianto inhibitorja poti tkivnega faktorja
US7534765B2 (en) 2005-09-27 2009-05-19 Stem Cell Therapeutics Corp. Pregnancy-induced oligodendrocyte precursor cell proliferation regulated by prolactin
TWI705820B (zh) * 2018-06-22 2020-10-01 美商美國禮來大藥廠 Gip/glp1促效劑組合物
US11097023B1 (en) * 2020-07-02 2021-08-24 Par Pharmaceutical, Inc. Pre-filled syringe containing sugammadex

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080879B1 (de) * 1981-11-28 1986-10-01 Sunstar Kabushiki Kaisha Stabilisiertes Interferon enthaltende pharmazeutische Zusammensetzung
JPS6069037A (ja) * 1983-09-26 1985-04-19 Sunstar Inc エリテマト−デス治療用外用剤
US4605555A (en) * 1984-09-20 1986-08-12 Sun Star Kabushiki Kaisha Composition and method for treating keratosic disorder of skin and mucosa
EP0284249A1 (de) * 1987-03-13 1988-09-28 Interferon Sciences, Inc. Gefriergetrocknete Lymphokin-Zusammensetzung
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
DE68907066T2 (de) * 1988-01-29 1993-12-16 Koken Kk Verbesserte Formulierungen mit kontrollierter Abgabe.
US5126324A (en) * 1990-06-07 1992-06-30 Genentech, Inc. Method of enhancing growth in patients using combination therapy
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
US5374620A (en) * 1990-06-07 1994-12-20 Genentech, Inc. Growth-promoting composition and its use
NZ262634A (en) * 1993-02-23 1997-02-24 Genentech Inc Stabilizing polypeptides against degradation by organic solvents by admixing the peptide with trehalose or mannitol
IT1272252B (it) * 1994-05-16 1997-06-16 Applied Research Systems Formulazioni liquide di interferone beta
JP2758154B2 (ja) * 1995-04-06 1998-05-28 エフ・ホフマン−ラ ロシユ アーゲー インターフェロンを含む液体製剤
US6511811B1 (en) * 1995-06-07 2003-01-28 The Regents Of The University Of California Protein kinase C antagonist related to insulin receptor
US5977057A (en) * 1996-05-08 1999-11-02 The University Of Vermont And State Agricultural College Thrombosis prophylaxis for factor VLEIDEN carriers
US5783556A (en) * 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
DE19825736C2 (de) * 1997-06-11 2003-09-18 Hyundai Electronics Ind Verfahren zum Bilden eines Kondensators einer Halbleitervorrichtung
US6663899B2 (en) * 1997-06-13 2003-12-16 Genentech, Inc. Controlled release microencapsulated NGF formulation
US6887462B2 (en) * 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta

Also Published As

Publication number Publication date
PT1069912E (pt) 2007-09-14
ES2288018T3 (es) 2007-12-16
AU3473999A (en) 1999-10-25
EP1069912A1 (de) 2001-01-24
DE69936638D1 (de) 2007-09-06
EP1069912B1 (de) 2007-07-25
WO1999051272A1 (en) 1999-10-14
JP2002510653A (ja) 2002-04-09
DE69936638T2 (de) 2008-05-21
ATE367828T1 (de) 2007-08-15
US20070249522A1 (en) 2007-10-25

Similar Documents

Publication Publication Date Title
CO5090908A1 (es) Procedimiento para administrar peptidos insulinotropicos
PT1093819E (pt) Compostos e composicoes para fornecimento de agentes activos
TWI262925B (en) GLP-1 analogues
HK1054918A1 (en) Compounds and compositions for delivering active agents
ATE270898T1 (de) Stabile igf/igfbp pharmazeutische formulierungen
MXPA01008611A (es) Compuestos y composiciones para suministrar agentes activos.
HUP0004447A2 (hu) Stabilizált teriparatid oldatok
EA200300026A1 (ru) Аналоги глюкагоноподобного пептида-1
DK1069912T3 (da) Injicerbare IGF-formuleringer, der indeholder succinat som puffermiddel
HK1036970A1 (en) Compounds and compositions for delivering active agents.
ATE311373T1 (de) Oxadiazolverbindungen und -zusammensetzungen zur abgabe von wirkstoffen
RS105704A (sr) Kiseli preparati insulina sa poboljšanom stabilnošću
AR021370A1 (es) Composiciones farmaceuticas inyectables estabilizadas que contienen agentes anti-neoplasicos taxoides
MX9202328A (es) Composicion farmaceutica local que contiene un compuesto alilamina como el agente activo.
MY128850A (en) Non-aqueous polar aprotic peptide formulations
MY121684A (en) Non-aqueous protic peptide formulations
WO2000034331A3 (en) Analogues of glp-1
NO20045507L (no) Injiserbare faste hyaluronsyrebaerere for levering av osteogene proteiner
RS50046B (sr) Farmaceutske kompozicije tizoksanida i nitazoksanida
AU4419497A (en) Pharmaceutical formulations of corticotropin releasing factor having improved stability in liquid form
MX9301387A (es) Metodo y composicion para el tratamiento de osteoporosis.
ES2174838T3 (es) Metodo para aumentar la absorcion del intestino.
ATE245028T1 (de) Trimegestone enthaltende pharmazeutische zusammensetzungen
AR020106A1 (es) Variantes estabilizadas del inhibidor de la subtilisina de streptomyces, gen mutante que la codifica y composicion que comprende dicha variante
MXPA05010390A (es) Composiciones y metodos para la liberacion de timosina beta 4, analogos, isoformas y otros derivados.