ATE367145T1 - Topische kosmetische und pharmazeutische mittel enthaltend spezifische alkoxilierte diester der fumarsäure - Google Patents
Topische kosmetische und pharmazeutische mittel enthaltend spezifische alkoxilierte diester der fumarsäureInfo
- Publication number
- ATE367145T1 ATE367145T1 AT00981789T AT00981789T ATE367145T1 AT E367145 T1 ATE367145 T1 AT E367145T1 AT 00981789 T AT00981789 T AT 00981789T AT 00981789 T AT00981789 T AT 00981789T AT E367145 T1 ATE367145 T1 AT E367145T1
- Authority
- AT
- Austria
- Prior art keywords
- fumaric acid
- agents
- egf
- alkoxilated
- diesters
- Prior art date
Links
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title abstract 5
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title abstract 4
- 239000001530 fumaric acid Substances 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 title 1
- 150000005690 diesters Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 101000871708 Homo sapiens Proheparin-binding EGF-like growth factor Proteins 0.000 abstract 3
- 102100033762 Proheparin-binding EGF-like growth factor Human genes 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 229940000033 dermatological agent Drugs 0.000 abstract 2
- 239000003241 dermatological agent Substances 0.000 abstract 2
- -1 fumaric acid diester Chemical class 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 102100038778 Amphiregulin Human genes 0.000 abstract 1
- 108010033760 Amphiregulin Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000037365 barrier function of the epidermis Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 abstract 1
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 abstract 1
- LDCRTTXIJACKKU-ONEGZZNKSA-N dimethyl fumarate Chemical compound COC(=O)\C=C\C(=O)OC LDCRTTXIJACKKU-ONEGZZNKSA-N 0.000 abstract 1
- 229960004419 dimethyl fumarate Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
- 230000009759 skin aging Effects 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C07C69/593—Dicarboxylic acid esters having only one carbon-to-carbon double bond
- C07C69/60—Maleic acid esters; Fumaric acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36237799 | 1999-12-21 | ||
| JP2000093152 | 2000-03-30 | ||
| JP2000323637 | 2000-10-24 | ||
| JP2000341577 | 2000-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE367145T1 true ATE367145T1 (de) | 2007-08-15 |
Family
ID=27480808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00981789T ATE367145T1 (de) | 1999-12-21 | 2000-12-15 | Topische kosmetische und pharmazeutische mittel enthaltend spezifische alkoxilierte diester der fumarsäure |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7037489B2 (de) |
| EP (1) | EP1249237B1 (de) |
| JP (1) | JP3908953B2 (de) |
| AT (1) | ATE367145T1 (de) |
| AU (1) | AU1893001A (de) |
| DE (1) | DE60035613T2 (de) |
| WO (1) | WO2001045697A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004068931A2 (en) * | 2003-02-07 | 2004-08-19 | Protein Design Labs Inc. | Amphiregulin antibodies and their use to treat cancer and psoriasis |
| WO2007148744A1 (ja) * | 2006-06-21 | 2007-12-27 | Santen Pharmaceutical Co., Ltd. | フマル酸誘導体を有効成分として含む角結膜障害の予防または治療剤 |
| ATE554769T1 (de) * | 2006-12-06 | 2012-05-15 | Cornell Res Foundation Inc | Neuromuskuläre blocker mit mittlerer dauer und antagonisten advon |
| US8592451B2 (en) | 2009-03-17 | 2013-11-26 | Cornell University | Reversible nondepolarizing neuromuscular blockade agents and methods for their use |
| CN102573794B (zh) | 2009-08-19 | 2017-03-15 | 康奈尔大学 | 供生理注射用的半胱氨酸 |
| JP5521025B2 (ja) * | 2012-12-21 | 2014-06-11 | 日本精化株式会社 | 浸透促進剤 |
| US10993657B1 (en) * | 2015-12-30 | 2021-05-04 | Halo Wearables, Llc | Wearable hydration monitor sensors |
| JP7678518B2 (ja) * | 2019-06-21 | 2025-05-16 | ポーラ化成工業株式会社 | スタフィロコッカス・ホミニス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ｈｏｍｉｎｉｓ）を有効成分とする肌状態改善剤 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2621214C3 (de) * | 1976-05-13 | 1981-11-12 | Koronis Gmbh Chemisch-Pharmazeutische Praeparate, 5441 Sassen | Verwendung von Stabilisatoren in Arzneimitteln mit Fumarsäuremonoäthylester und desen Mineralsalzen |
| US5149695A (en) * | 1985-01-15 | 1992-09-22 | Speiser Peter P | Fumaric acid derivatives, process for the production thereof and pharmaceutical compositions containing same |
| JPH0418017A (ja) | 1990-05-09 | 1992-01-22 | Noevir Co Ltd | 皮脂分泌促進剤 |
| US5342880A (en) * | 1992-03-20 | 1994-08-30 | Neste Resins Corporation | Phenolic resol plywood resin, manufacture and use |
| US5455025A (en) * | 1992-04-02 | 1995-10-03 | Croda, Inc. | Non-aqueous emollient compositions for topical application |
| US5837728A (en) * | 1995-01-27 | 1998-11-17 | Molecular Design International | 9-cis retinoic acid esters and amides and uses thereof |
| JPH09255622A (ja) * | 1996-03-26 | 1997-09-30 | Nof Corp | 水溶性フマル酸ジエステルの製造方法 |
| JP3916786B2 (ja) * | 1998-12-18 | 2007-05-23 | 花王株式会社 | 皮膚化粧料 |
-
2000
- 2000-12-15 AT AT00981789T patent/ATE367145T1/de not_active IP Right Cessation
- 2000-12-15 JP JP2001546636A patent/JP3908953B2/ja not_active Expired - Fee Related
- 2000-12-15 US US10/169,040 patent/US7037489B2/en not_active Expired - Fee Related
- 2000-12-15 DE DE60035613T patent/DE60035613T2/de not_active Expired - Lifetime
- 2000-12-15 WO PCT/JP2000/008942 patent/WO2001045697A1/ja not_active Ceased
- 2000-12-15 EP EP00981789A patent/EP1249237B1/de not_active Expired - Lifetime
- 2000-12-15 AU AU18930/01A patent/AU1893001A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7037489B2 (en) | 2006-05-02 |
| EP1249237A4 (de) | 2005-03-23 |
| AU1893001A (en) | 2001-07-03 |
| EP1249237A1 (de) | 2002-10-16 |
| US20030185786A1 (en) | 2003-10-02 |
| EP1249237B1 (de) | 2007-07-18 |
| WO2001045697A1 (en) | 2001-06-28 |
| DE60035613D1 (de) | 2007-08-30 |
| JP3908953B2 (ja) | 2007-04-25 |
| DE60035613T2 (de) | 2008-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6423854B1 (en) | Aminophenol derivatives and their use in cosmetics | |
| NZ515142A (en) | Pharmaceutical composition | |
| ATE252529T1 (de) | Colchinolderivate als gefässschädigende mittel | |
| BR9811099A (pt) | Inibidores de urocinase | |
| MX9307779A (es) | Compuestos benzoicos fundidos. | |
| AR015649A1 (es) | Inhibidores de isoprenil-transferasas proteicas, composiciones que los comprenden y el uso de los mismos para la fabricacion de un medicamento | |
| MY119231A (en) | Novel lipoic acid derivatives, their preparation, and pharmaceutical compositions containing them | |
| DE69534564D1 (de) | Verwendung von 2-hydroxy-5-phenylazobenzoesäure-derivaten als wirkstoffe zur chemoprävention und chemotherapie von kolonkrebs | |
| ATE302778T1 (de) | N-substituierte 4-aminopteridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
| US6326014B1 (en) | Use of oxamate derivatives as depigmenting agents | |
| ZA911728B (en) | Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors | |
| US20040071647A1 (en) | Use of metalloprotease inhibitors to induce and/or stimulate the growth of head hair or other hairs and/or to slow down their loss | |
| ATE367145T1 (de) | Topische kosmetische und pharmazeutische mittel enthaltend spezifische alkoxilierte diester der fumarsäure | |
| DE69806962D1 (de) | Verwendung von nmifa als entzündungshemmer in oberflächlichem saugetier-gewebe | |
| DE69512589D1 (de) | Behandlung von durch Talgdrüse verursachten Erkrankungen mit Inhibitoren der Acyl CoA Cholesterin Acyltransferase | |
| DE69412049D1 (de) | Hemmung von dysfunctionalen Uterusblutungen | |
| DK0825197T3 (da) | Nye 6-hydroxy- og 6-oxo-androstanderivater, der er aktive i forhold til det cardiovaskulære system, og farmaceutiske præpar | |
| ATE253359T1 (de) | Antithrombotische mittel | |
| GEP19991872B (en) | Novel Taxoids, Preparations Thereof, and Pharmaceutical Compositions Containing Same | |
| DK0437120T3 (da) | Pyridonderivater, deres fremstilling og anvendelse som lægemidler samt farmaceutiske præparater med indhold heraf og hidtil ukendte mellemprodukter | |
| ATE286395T1 (de) | Antithrombotische mittel | |
| NO973401L (no) | Kortikosteroidinneholdende sammensetninger og fremstilling derav | |
| ATE204741T1 (de) | Dimere säuren in kosmetika und arzneimitteln | |
| FR2757164B1 (fr) | Nouveaux derives de n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
| TR199802665T2 (xx) | Piperidin asetik asit t�revleri ve bunlar�n trombotik hastal�klar�n tedavisinde kullan�m�. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |