ATE365214T1 - Ligand des zelleintritt-vermittelnden proteins von herpes simplex und methoden zu dessen verwendungen - Google Patents

Ligand des zelleintritt-vermittelnden proteins von herpes simplex und methoden zu dessen verwendungen

Info

Publication number
ATE365214T1
ATE365214T1 AT01926879T AT01926879T ATE365214T1 AT E365214 T1 ATE365214 T1 AT E365214T1 AT 01926879 T AT01926879 T AT 01926879T AT 01926879 T AT01926879 T AT 01926879T AT E365214 T1 ATE365214 T1 AT E365214T1
Authority
AT
Austria
Prior art keywords
methods
herpes simplex
herpes virus
cell entry
protein ligand
Prior art date
Application number
AT01926879T
Other languages
English (en)
Inventor
Carl Ware
Original Assignee
Jolla Inst Allergy Immunolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jolla Inst Allergy Immunolog filed Critical Jolla Inst Allergy Immunolog
Application granted granted Critical
Publication of ATE365214T1 publication Critical patent/ATE365214T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
AT01926879T 2000-04-12 2001-04-11 Ligand des zelleintritt-vermittelnden proteins von herpes simplex und methoden zu dessen verwendungen ATE365214T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54909600A 2000-04-12 2000-04-12

Publications (1)

Publication Number Publication Date
ATE365214T1 true ATE365214T1 (de) 2007-07-15

Family

ID=24191643

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05023967T ATE483807T1 (de) 2000-04-12 2001-04-11 Ligand des zelleintritt-vermittelnden proteins von herpes simplex und methoden zu dessen verwendungen
AT01926879T ATE365214T1 (de) 2000-04-12 2001-04-11 Ligand des zelleintritt-vermittelnden proteins von herpes simplex und methoden zu dessen verwendungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT05023967T ATE483807T1 (de) 2000-04-12 2001-04-11 Ligand des zelleintritt-vermittelnden proteins von herpes simplex und methoden zu dessen verwendungen

Country Status (10)

Country Link
EP (2) EP1674575B1 (de)
JP (1) JP2003531152A (de)
AT (2) ATE483807T1 (de)
AU (1) AU5338701A (de)
CA (1) CA2406132C (de)
CY (1) CY1111293T1 (de)
DE (2) DE60129010T2 (de)
DK (1) DK1674575T3 (de)
ES (1) ES2352742T3 (de)
PT (1) PT1674575E (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007010692A1 (ja) * 2005-07-19 2007-01-25 Japan Science And Technology Agency Hvem及びbtlaを標的とした炎症性腸疾患治療用医薬組成物及び治療方法
AU2009308707A1 (en) 2008-10-31 2010-05-06 Biogen Idec Ma Inc. LIGHT targeting molecules and uses thereof
GB201701194D0 (en) 2017-01-24 2017-03-08 Capella Bioscience Ltd Antigen binding molecules that bind light
US11312781B2 (en) 2018-01-24 2022-04-26 Capella Bioscience Ltd. Antigen binding molecules that bind LIGHT
US11708406B2 (en) 2020-04-01 2023-07-25 Avalo Therapeutics, Inc. Method of treating acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) associate with COVID-19 by administering an anti-LIGHT antibody
CN111991551A (zh) * 2020-07-31 2020-11-27 中国人民解放军海军军医大学 Traf3半胱氨酸突变体在制备抗病毒药物中的应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291207B1 (en) * 1995-07-28 2001-09-18 Northwestern University Herpes virus entry receptor protein
JP2000508522A (ja) * 1996-03-22 2000-07-11 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド アポトーシス誘導分子ii
US6479254B2 (en) * 1996-03-22 2002-11-12 Human Genome Sciences, Inc. Apoptosis inducing molecule II
DE69730607T2 (de) * 1996-07-19 2005-01-27 Takeda Chemical Industries, Ltd. Fas ligand ähnliches protein, seine herstellung und verwendung
IL129527A (en) * 1996-10-25 2006-12-10 Biogen Idec Inc Pharmaceutical preparations containing soluble lymphoxine-beta receptors
WO1998018824A1 (en) * 1996-10-30 1998-05-07 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like 2
AU5516898A (en) * 1996-12-12 1998-07-03 Genentech Inc. Hvem polypeptides and uses thereof
EP1009431A4 (de) * 1997-05-12 2000-09-27 Smithkline Beckman Corp Antikörper gegen den menschlichen tumornekrosefaktor-rezeptor des typs 2 (tr2)
US6140467A (en) * 1997-07-07 2000-10-31 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6346388B1 (en) * 1997-08-13 2002-02-12 Smithkline Beecham Corporation Method of identifying agonist and antagonists for tumor necrosis related receptors TR1 and TR2
WO1999011662A1 (en) 1997-09-05 1999-03-11 Millennium Biotherapeutics, Inc. Novel molecules of the tnfr-ligand-related protein family and uses thereof
WO1999042584A1 (en) * 1998-02-20 1999-08-26 Human Genome Sciences, Inc. Apoptosis inducing molecule ii and methods of use
AU5568799A (en) * 1998-08-18 2000-03-14 Northwestern University Peptides for inhibition of herpes simplex virus entry
JP2002529051A (ja) 1998-09-03 2002-09-10 ミレニアム・ファーマシューティカルズ・インコーポレイテッド ヘルペスウイルス侵入メディエーター関連タンパク質ファミリーの新規分子およびその使用
KR100888832B1 (ko) * 1998-10-09 2009-03-17 바이오겐 아이덱 엠에이 인코포레이티드 림프독소 베타 경로의 차단에 의한 바이러스-유도성 전신 쇼크 및 호흡 장애의 반전
EP1161261A1 (de) * 1999-03-11 2001-12-12 Human Genome Sciences, Inc. Apoptose-induzierendes molekül ii und verwendungsverfahren

Also Published As

Publication number Publication date
CA2406132C (en) 2012-07-03
PT1674575E (pt) 2010-12-06
ATE483807T1 (de) 2010-10-15
CY1111293T1 (el) 2015-08-05
DK1674575T3 (da) 2010-11-29
EP1274840A2 (de) 2003-01-15
EP1674575A2 (de) 2006-06-28
EP1274840B1 (de) 2007-06-20
ES2352742T3 (es) 2011-02-22
CA2406132A1 (en) 2001-10-25
EP1674575A3 (de) 2007-08-08
DE60129010T2 (de) 2008-02-28
DE60143231D1 (de) 2010-11-18
AU5338701A (en) 2001-10-30
EP1674575B1 (de) 2010-10-06
DE60129010D1 (de) 2007-08-02
JP2003531152A (ja) 2003-10-21

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