ATE359261T1 - Neue phenylethanolaminverbindungen mit erregender wirkung an beta2-akzeptor und verfahren zu deren herstellung - Google Patents

Neue phenylethanolaminverbindungen mit erregender wirkung an beta2-akzeptor und verfahren zu deren herstellung

Info

Publication number
ATE359261T1
ATE359261T1 AT02771983T AT02771983T ATE359261T1 AT E359261 T1 ATE359261 T1 AT E359261T1 AT 02771983 T AT02771983 T AT 02771983T AT 02771983 T AT02771983 T AT 02771983T AT E359261 T1 ATE359261 T1 AT E359261T1
Authority
AT
Austria
Prior art keywords
carbon atoms
compounds
beta2
acceptor
new
Prior art date
Application number
AT02771983T
Other languages
English (en)
Inventor
Maosheng Cheng
Li Pan
Lei Ji
Li Zhang
Jianmin Shen
Guilan Song
Zhiqing Li
Original Assignee
Univ Shenyang Pharmaceutical
Jinzhou Jiutai Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Shenyang Pharmaceutical, Jinzhou Jiutai Pharmaceutical filed Critical Univ Shenyang Pharmaceutical
Application granted granted Critical
Publication of ATE359261T1 publication Critical patent/ATE359261T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/68—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02771983T 2001-09-30 2002-09-25 Neue phenylethanolaminverbindungen mit erregender wirkung an beta2-akzeptor und verfahren zu deren herstellung ATE359261T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB011282347A CN1276911C (zh) 2001-09-30 2001-09-30 具有β2－受体兴奋作用的新型苯乙醇胺类化合物及其制法

Publications (1)

Publication Number Publication Date
ATE359261T1 true ATE359261T1 (de) 2007-05-15

Family

ID=4668112

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02771983T ATE359261T1 (de) 2001-09-30 2002-09-25 Neue phenylethanolaminverbindungen mit erregender wirkung an beta2-akzeptor und verfahren zu deren herstellung

Country Status (11)

Country Link
US (1) US7098364B2 (de)
EP (1) EP1439164B1 (de)
JP (1) JP3990399B2 (de)
CN (1) CN1276911C (de)
AT (1) ATE359261T1 (de)
AU (1) AU2002338124A1 (de)
DE (1) DE60219500T2 (de)
DK (1) DK1439164T3 (de)
ES (1) ES2284926T3 (de)
RU (1) RU2264382C1 (de)
WO (1) WO2003093219A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100497296C (zh) * 2006-07-07 2009-06-10 沈阳药科大学 旋光活性的苯乙醇胺类化合物及其制法
CN100431535C (zh) * 2006-09-18 2008-11-12 锦州九泰药业有限责任公司 一种盐酸川丁特罗气雾剂
EP1969929A1 (de) * 2007-03-12 2008-09-17 Bayer CropScience AG Substituierte Phenylamidine und deren Verwendung als Fungizide
CN102477000B (zh) * 2010-11-24 2013-11-06 沈阳药科大学 一种苯乙醇胺类化合物的合成方法
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
CN106279018B (zh) * 2015-06-26 2019-01-29 沈阳药科大学 β2-受体兴奋剂及其制备方法和应用
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
CN120583945A (zh) 2023-01-20 2025-09-02 阿托基公司 用于治疗或预防肌肉消耗的β2-肾上腺素能受体激动剂
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses
GB202403169D0 (en) 2024-03-05 2024-04-17 Atrogi Ab New medical uses
WO2025238248A1 (en) 2024-05-17 2025-11-20 Atrogi Ab USE OF β2-ADRENERGIC RECEPTOR AGONISTS IN TREATING MUSCLE WASTING

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028398A1 (de) * 1990-09-07 1992-03-12 Thomae Gmbh Dr K Phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
SG55296A1 (en) * 1996-04-12 1998-12-21 Kissei Pharmaceutical Phenylethalolaminotetralincarboxamide derivatives
CN1237574A (zh) * 1998-05-29 1999-12-08 中国科学院成都有机化学研究所 合成苯乙醇胺类化合物的方法

Also Published As

Publication number Publication date
DE60219500D1 (de) 2007-05-24
JP3990399B2 (ja) 2007-10-10
DE60219500T2 (de) 2007-12-13
EP1439164B1 (de) 2007-04-11
US7098364B2 (en) 2006-08-29
AU2002338124A1 (en) 2003-11-17
EP1439164A1 (de) 2004-07-21
DK1439164T3 (da) 2007-08-20
HK1064664A1 (en) 2005-02-04
CN1276911C (zh) 2006-09-27
EP1439164A4 (de) 2005-12-21
RU2004112212A (ru) 2005-09-10
WO2003093219A1 (en) 2003-11-13
US20040266867A1 (en) 2004-12-30
CN1408703A (zh) 2003-04-09
RU2264382C1 (ru) 2005-11-20
ES2284926T3 (es) 2007-11-16
AU2002338124A8 (en) 2003-11-17
JP2005519989A (ja) 2005-07-07

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