ATE314852T1 - Verwendung von 1,4-benzothiazepinen zur herstellung eines medikaments zur behandlung der vorhof-fibrillation - Google Patents

Verwendung von 1,4-benzothiazepinen zur herstellung eines medikaments zur behandlung der vorhof-fibrillation

Info

Publication number
ATE314852T1
ATE314852T1 AT99961438T AT99961438T ATE314852T1 AT E314852 T1 ATE314852 T1 AT E314852T1 AT 99961438 T AT99961438 T AT 99961438T AT 99961438 T AT99961438 T AT 99961438T AT E314852 T1 ATE314852 T1 AT E314852T1
Authority
AT
Austria
Prior art keywords
atrial fibrillation
group
treatment
lower alkoxy
benzothiazepines
Prior art date
Application number
AT99961438T
Other languages
English (en)
Inventor
Kazuo Aisaka
Naoya Imagawa
Hisato Miyai
Satoshi Ogawa
Noboru Kaneko
Original Assignee
Noboru Kaneko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noboru Kaneko filed Critical Noboru Kaneko
Application granted granted Critical
Publication of ATE314852T1 publication Critical patent/ATE314852T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
AT99961438T 1998-12-28 1999-12-27 Verwendung von 1,4-benzothiazepinen zur herstellung eines medikaments zur behandlung der vorhof-fibrillation ATE314852T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP37333298 1998-12-28

Publications (1)

Publication Number Publication Date
ATE314852T1 true ATE314852T1 (de) 2006-02-15

Family

ID=18501984

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99961438T ATE314852T1 (de) 1998-12-28 1999-12-27 Verwendung von 1,4-benzothiazepinen zur herstellung eines medikaments zur behandlung der vorhof-fibrillation

Country Status (6)

Country Link
US (1) US6506745B1 (de)
EP (1) EP1147772B1 (de)
AT (1) ATE314852T1 (de)
CA (1) CA2357038C (de)
DE (1) DE69929362T2 (de)
WO (1) WO2000038688A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE314852T1 (de) 1998-12-28 2006-02-15 Noboru Kaneko Verwendung von 1,4-benzothiazepinen zur herstellung eines medikaments zur behandlung der vorhof-fibrillation
US7718644B2 (en) * 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US20040229781A1 (en) * 2000-05-10 2004-11-18 Marks Andrew Robert Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias
US7393652B2 (en) * 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
US20060293266A1 (en) * 2000-05-10 2006-12-28 The Trustees Of Columbia Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure
US7879840B2 (en) * 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US20040048780A1 (en) * 2000-05-10 2004-03-11 The Trustees Of Columbia University In The City Of New York Method for treating and preventing cardiac arrhythmia
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US6489125B1 (en) * 2000-05-10 2002-12-03 The Trustees Of Columbia University In The City Of New York Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor
US7544678B2 (en) * 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
JP2007525165A (ja) 2003-03-07 2007-09-06 トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク タイプ１ライアノジン受容体に基づく方法
US8710045B2 (en) * 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) * 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
PL3176164T3 (pl) 2014-07-30 2020-05-18 Aetas Pharma Co. Ltd. Izomer optyczny pochodnej 1-tlenku 1,4-benzotiazepiny oraz farmaceutyczna kompozycja wytworzona z jego użyciem
EP3725315B1 (de) 2017-12-11 2023-10-04 Aetas Pharma Co. Ltd. Medikament zur verbesserung einer nierenfunktionsstörung mit einem optischen isomer eines 1,4-benzothiazepin-1-oxid-derivats

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8707121D0 (en) * 1987-03-25 1987-04-29 Pfizer Ltd Antiarrhythmic agents
JPH0749807B2 (ja) 1987-05-15 1995-05-31 清隆 滝本 埋込式固形潤滑剤
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
JP2703408B2 (ja) * 1990-12-28 1998-01-26 麒麟麦酒株式会社 １，４‐ベンゾチアゼピン誘導体
JPH0565721A (ja) 1991-09-05 1993-03-19 Iseki & Co Ltd 操作レバーの制御パターン切替装置
ATE314852T1 (de) 1998-12-28 2006-02-15 Noboru Kaneko Verwendung von 1,4-benzothiazepinen zur herstellung eines medikaments zur behandlung der vorhof-fibrillation

Also Published As

Publication number Publication date
US6506745B1 (en) 2003-01-14
CA2357038C (en) 2008-10-21
CA2357038A1 (en) 2000-07-06
DE69929362D1 (de) 2006-03-30
EP1147772A4 (de) 2002-07-10
EP1147772A1 (de) 2001-10-24
DE69929362T2 (de) 2006-09-28
WO2000038688A1 (fr) 2000-07-06
EP1147772B1 (de) 2006-01-04

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