ATE358727T1 - Rekombinante bifunktionale fusionsproteine zur abtreibung variabler viren - Google Patents
Rekombinante bifunktionale fusionsproteine zur abtreibung variabler virenInfo
- Publication number
- ATE358727T1 ATE358727T1 AT00973003T AT00973003T ATE358727T1 AT E358727 T1 ATE358727 T1 AT E358727T1 AT 00973003 T AT00973003 T AT 00973003T AT 00973003 T AT00973003 T AT 00973003T AT E358727 T1 ATE358727 T1 AT E358727T1
- Authority
- AT
- Austria
- Prior art keywords
- component
- bifunctional fusion
- exporation
- fusion proteins
- recombinant bifunctional
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 2
- 230000001588 bifunctional effect Effects 0.000 title abstract 2
- 102000037865 fusion proteins Human genes 0.000 title abstract 2
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 101710154606 Hemagglutinin Proteins 0.000 abstract 1
- 201000005505 Measles Diseases 0.000 abstract 1
- 241000712079 Measles morbillivirus Species 0.000 abstract 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 abstract 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 abstract 1
- 101710176177 Protein A56 Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 210000005260 human cell Anatomy 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/165—Mumps or measles virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9925966.5A GB9925966D0 (en) | 1999-11-02 | 1999-11-02 | Threapeutic vaccines against variable viruses and other targets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE358727T1 true ATE358727T1 (de) | 2007-04-15 |
Family
ID=10863838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00973003T ATE358727T1 (de) | 1999-11-02 | 2000-11-01 | Rekombinante bifunktionale fusionsproteine zur abtreibung variabler viren |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7390881B2 (enExample) |
| EP (1) | EP1226256B1 (enExample) |
| JP (1) | JP4768944B2 (enExample) |
| AT (1) | ATE358727T1 (enExample) |
| AU (1) | AU1156001A (enExample) |
| CA (1) | CA2389339A1 (enExample) |
| DE (1) | DE60034243T2 (enExample) |
| ES (1) | ES2284537T3 (enExample) |
| GB (1) | GB9925966D0 (enExample) |
| HK (1) | HK1048335B (enExample) |
| WO (1) | WO2001032893A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8029803B2 (en) | 2002-06-20 | 2011-10-04 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| US8007805B2 (en) | 2003-08-08 | 2011-08-30 | Paladin Labs, Inc. | Chimeric antigens for breaking host tolerance to foreign antigens |
| WO2005027964A1 (en) * | 2003-09-15 | 2005-03-31 | Id Biomedical Corporation Of Quebec | Measles subunit vaccine |
| WO2006133497A1 (en) * | 2005-06-15 | 2006-12-21 | Adelaide Research & Innovation Pty Ltd | Combination treatment |
| ES2337113B1 (es) * | 2007-04-17 | 2011-01-24 | Centre De Recerca En Sanitat Animal (Cresa) | Empleo de la hemaglutinina del virus de la peste porcina africana como adyuvante. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021325A1 (en) * | 1992-04-08 | 1993-10-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Wild-type measles virus glycoproteins: vaccine and detection method therefor |
| EP0966534B1 (en) * | 1997-03-11 | 2005-02-02 | Mayo Foundation for Medical Education and Research | Compositions and methods for elimination of unwanted cells |
| WO1999064073A2 (en) | 1998-06-11 | 1999-12-16 | The Government Of The United States, Represented By The Secretary Of The Department Of Health And Huan Services | Recombinant immunotoxin directed against the hiv-1 gp120 envelope glycoprotein |
| DE60040136D1 (de) | 1999-03-16 | 2008-10-16 | Us Gov Nat Inst Health | Ein neues chimäres protein für die prävention und die behandlung einer hiv infektion |
-
1999
- 1999-11-02 GB GBGB9925966.5A patent/GB9925966D0/en not_active Ceased
-
2000
- 2000-11-01 CA CA002389339A patent/CA2389339A1/en not_active Abandoned
- 2000-11-01 JP JP2001535575A patent/JP4768944B2/ja not_active Expired - Fee Related
- 2000-11-01 WO PCT/GB2000/004191 patent/WO2001032893A1/en not_active Ceased
- 2000-11-01 AT AT00973003T patent/ATE358727T1/de not_active IP Right Cessation
- 2000-11-01 EP EP00973003A patent/EP1226256B1/en not_active Expired - Lifetime
- 2000-11-01 ES ES00973003T patent/ES2284537T3/es not_active Expired - Lifetime
- 2000-11-01 DE DE60034243T patent/DE60034243T2/de not_active Expired - Lifetime
- 2000-11-01 HK HK03100373.4A patent/HK1048335B/en not_active IP Right Cessation
- 2000-11-01 AU AU11560/01A patent/AU1156001A/en not_active Abandoned
-
2005
- 2005-05-09 US US11/124,971 patent/US7390881B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2389339A1 (en) | 2001-05-10 |
| US20050260220A1 (en) | 2005-11-24 |
| JP2003514518A (ja) | 2003-04-22 |
| DE60034243T2 (de) | 2007-12-20 |
| EP1226256B1 (en) | 2007-04-04 |
| US7390881B2 (en) | 2008-06-24 |
| GB9925966D0 (en) | 1999-12-29 |
| WO2001032893A1 (en) | 2001-05-10 |
| DE60034243D1 (de) | 2007-05-16 |
| JP4768944B2 (ja) | 2011-09-07 |
| ES2284537T3 (es) | 2007-11-16 |
| EP1226256A1 (en) | 2002-07-31 |
| HK1048335A1 (en) | 2003-03-28 |
| AU1156001A (en) | 2001-05-14 |
| HK1048335B (en) | 2007-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |