ATE353019T1 - Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung - Google Patents

Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung

Info

Publication number
ATE353019T1
ATE353019T1 AT96941503T AT96941503T ATE353019T1 AT E353019 T1 ATE353019 T1 AT E353019T1 AT 96941503 T AT96941503 T AT 96941503T AT 96941503 T AT96941503 T AT 96941503T AT E353019 T1 ATE353019 T1 AT E353019T1
Authority
AT
Austria
Prior art keywords
stereoisomers
fatty acid
diagnostic imaging
acid analogues
imaging agents
Prior art date
Application number
AT96941503T
Other languages
German (de)
English (en)
Inventor
David R Elmaleh
Original Assignee
Molecular Insight Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Insight Pharm Inc filed Critical Molecular Insight Pharm Inc
Application granted granted Critical
Publication of ATE353019T1 publication Critical patent/ATE353019T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Nuclear Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT96941503T 1995-12-01 1996-11-25 Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung ATE353019T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US786395P 1995-12-01 1995-12-01

Publications (1)

Publication Number Publication Date
ATE353019T1 true ATE353019T1 (de) 2007-02-15

Family

ID=21728502

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96941503T ATE353019T1 (de) 1995-12-01 1996-11-25 Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung
AT06025944T ATE526995T1 (de) 1995-12-01 1996-11-25 Stereoisomers von fettsäureanalogen für diagnostische bildgebung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06025944T ATE526995T1 (de) 1995-12-01 1996-11-25 Stereoisomers von fettsäureanalogen für diagnostische bildgebung

Country Status (8)

Country Link
US (4) US7005119B2 (enExample)
EP (2) EP0869821B1 (enExample)
JP (3) JP4272259B2 (enExample)
AT (2) ATE353019T1 (enExample)
CA (1) CA2238860C (enExample)
DE (1) DE69636881T2 (enExample)
ES (2) ES2374743T3 (enExample)
WO (1) WO1997019705A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE353019T1 (de) * 1995-12-01 2007-02-15 Molecular Insight Pharm Inc Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung
US20090117032A1 (en) * 1998-09-08 2009-05-07 The General Hospital Corporation Imaging Agents for Early Detection and Monitoring of Cardiovascular Plaque
EP0992245A1 (en) * 1998-09-16 2000-04-12 Goldham Bioglan Pharma GmbH Radio-contrast agents
EP1040825A1 (en) * 1999-03-11 2000-10-04 K.U. Leuven Research & Development Means for diagnosing bladder carcinoma
DE60030270T2 (de) * 1999-04-14 2007-08-30 Molecular Insight Pharmaceuticals, Inc., Cambridge Fettsaure analoge zur diagnose von kranzarterie erkrankungen
WO2003084575A1 (en) * 2002-04-01 2003-10-16 Biostream, Inc. Pendant fatty acid imaging agents
AU2004232297B2 (en) * 2003-04-17 2010-11-04 The General Hospital Corporation Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid
JP2012526129A (ja) * 2009-05-04 2012-10-25 ワシントン・ユニバーシティ 脂肪酸代謝および貯蔵を画像化するためのｐｅｔ放射性追跡子
DE102010010666A1 (de) * 2010-03-01 2011-09-01 Sven Reske Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6802651A (enExample) * 1968-02-23 1969-08-26
DE2828623C2 (de) * 1978-06-29 1983-11-17 Kernforschungsanlage Jülich GmbH, 5170 Jülich Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung
DE2947500C2 (de) * 1979-11-24 1984-05-10 Dutschka, Klaus, 4300 Essen Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber
FR2508902B1 (fr) * 1981-07-02 1985-09-06 Commissariat Energie Atomique Procede de preparation extemporanee d'un acide gras injectable, marque a l'iode radioactif et preparation de derives iodes utilisables pour la mise en oeuvre de ce procede
US4524059A (en) * 1983-01-28 1985-06-18 The General Hospital Corporation Fatty acid analogs
US4942231A (en) * 1984-05-24 1990-07-17 Mallinckrodt, Inc. Method of preparing a chlorinated, brominated, radio-brominated, iodinated and/or radioiodinated aromatic or heteroaromatic compound
CA1243329A (en) * 1985-03-11 1988-10-18 Amersham Int Plc TECHNETIUM COMPLEXES WITH PROPYLENE-AMINE-OXIMES
US4746505A (en) * 1985-04-26 1988-05-24 President And Fellows Of Harvard College Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands
US4764358A (en) * 1985-04-30 1988-08-16 The United States Of America As Represented By The United States Department Of Energy Radiolabeled dimethyl branched long chain fatty acid for heart imaging
US4877599A (en) 1986-11-10 1989-10-31 New England Deaconess Hospital Corporation Detection of vascular disease with labelled antibodies
ATE89271T1 (de) * 1987-11-19 1993-05-15 Univ Vanderbilt Radiojodhaltige benzamide und verfahren zu ihrer verwendung als radiobildende agenzien.
US5242681A (en) * 1990-03-12 1993-09-07 Research Corporation Technologies, Inc. Lipophilic contrast agents for diagnostic image analysis
US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
ATE353019T1 (de) * 1995-12-01 2007-02-15 Molecular Insight Pharm Inc Stereoisomere von fettsäureanalogen zur diagnostischen bildgebung
EP2324857A1 (en) * 1997-09-08 2011-05-25 The General Hospital Corporation Imaging agents for early detection of cardiovascular plaque
US7060251B1 (en) * 1997-09-08 2006-06-13 The General Hospital Corporation Imaging agents for early detection and monitoring of cardiovascular plaque
DE60030270T2 (de) * 1999-04-14 2007-08-30 Molecular Insight Pharmaceuticals, Inc., Cambridge Fettsaure analoge zur diagnose von kranzarterie erkrankungen
EP1265865A2 (en) * 2000-03-21 2002-12-18 The Procter & Gamble Company Difluorobutyric acid derivatives and their use as metalloprotease inhibitors
AU2004232297B2 (en) * 2003-04-17 2010-11-04 The General Hospital Corporation Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid

Also Published As

Publication number Publication date
ES2374743T3 (es) 2012-02-21
US7314609B2 (en) 2008-01-01
CA2238860C (en) 2009-01-13
US20080247948A1 (en) 2008-10-09
US7005119B2 (en) 2006-02-28
HK1102262A1 (en) 2007-11-09
CA2238860A1 (en) 1997-06-05
JP4937144B2 (ja) 2012-05-23
JP2012036215A (ja) 2012-02-23
EP1767224B1 (en) 2011-10-05
JP4272259B2 (ja) 2009-06-03
HK1016494A1 (en) 1999-11-05
EP0869821A4 (en) 2002-08-28
JP2000502059A (ja) 2000-02-22
ATE526995T1 (de) 2011-10-15
EP0869821A1 (en) 1998-10-14
EP1767224A2 (en) 2007-03-28
JP2008201774A (ja) 2008-09-04
US20030215386A1 (en) 2003-11-20
EP0869821B1 (en) 2007-01-31
DE69636881D1 (de) 2007-03-22
US20070128110A1 (en) 2007-06-07
WO1997019705A1 (en) 1997-06-05
EP1767224A3 (en) 2007-11-28
ES2281906T3 (es) 2007-10-01
DE69636881T2 (de) 2007-09-20
US20060078495A1 (en) 2006-04-13

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Legal Events

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