ATE348880T1 - Hbv mutanten und methoden für deren nachweis - Google Patents

Hbv mutanten und methoden für deren nachweis

Info

Publication number
ATE348880T1
ATE348880T1 AT97934385T AT97934385T ATE348880T1 AT E348880 T1 ATE348880 T1 AT E348880T1 AT 97934385 T AT97934385 T AT 97934385T AT 97934385 T AT97934385 T AT 97934385T AT E348880 T1 ATE348880 T1 AT E348880T1
Authority
AT
Austria
Prior art keywords
viral
present
detection
methods
assays
Prior art date
Application number
AT97934385T
Other languages
German (de)
English (en)
Inventor
Stephen Alister Locarnini
Angeline Ingrid Bartholomeusz
Thein Thein Aye
Man Robert A De
Original Assignee
Melbourne Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melbourne Health filed Critical Melbourne Health
Application granted granted Critical
Publication of ATE348880T1 publication Critical patent/ATE348880T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97934385T 1996-11-08 1997-08-15 Hbv mutanten und methoden für deren nachweis ATE348880T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPO3519A AUPO351996A0 (en) 1996-11-08 1996-11-08 Viral variants and methods for detecting same

Publications (1)

Publication Number Publication Date
ATE348880T1 true ATE348880T1 (de) 2007-01-15

Family

ID=3797830

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97934385T ATE348880T1 (de) 1996-11-08 1997-08-15 Hbv mutanten und methoden für deren nachweis

Country Status (9)

Country Link
US (4) US6555311B1 (https=)
EP (1) EP0964916B1 (https=)
JP (4) JP2001503277A (https=)
AT (1) ATE348880T1 (https=)
AU (1) AUPO351996A0 (https=)
CA (1) CA2270178C (https=)
DE (1) DE69737126T2 (https=)
ES (1) ES2279542T3 (https=)
WO (1) WO1998021317A1 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA973367B (en) * 1996-04-19 1997-11-18 Innogenetics Nv Method for typing and detecting HBV.
USRE40233E1 (en) 1996-11-08 2008-04-08 Melbourne Health Viral variants and methods for detecting same
AUPO351996A0 (en) * 1996-11-08 1996-12-05 Western Health Care Network Viral variants and methods for detecting same
AUPP706098A0 (en) * 1998-11-11 1998-12-03 North Western Health Care Network Biological compositions, components thereof and uses therefor
AUPP967999A0 (en) 1999-04-09 1999-05-06 North Western Health Care Network Viral variants
AR028149A1 (es) * 1999-07-08 2003-04-30 Innogenetics Nv Deteccion de la resistencia a los farmacos contra la hepatitis b
AUPQ810900A0 (en) 2000-06-09 2000-07-06 Austin and Repatriation Medical Centre, The Viral variants and methods of using same
SG90149A1 (en) * 2000-07-18 2002-07-23 Government Of The Republic Of Diagnostic assay
US6697858B1 (en) * 2000-08-14 2004-02-24 Telephony@Work Call center
JP4502642B2 (ja) * 2002-02-07 2010-07-14 メルボルン ヘルス ヌクレオシドアナログに対する感受性の変化を有するウイルス変種およびその使用
US7405039B2 (en) 2002-02-07 2008-07-29 Austin Health Viral variants with altered susceptibility to nucleoside analogs and uses thereof
TR200402517T1 (tr) * 2002-03-29 2007-12-24 Innogenetics N.V. HBV ilaç direnci tespit metotları
EP2033967A1 (en) 2002-04-12 2009-03-11 Melbourne Health Hepatitis B viral variants with reduced susceptibility to nucleoside analogs and uses thereof
AU2003213874B2 (en) * 2002-04-12 2008-12-04 Austin Health Hepatitis B viral variants with redused susceptibility to nucleoside analogs and uses thereof
EP1513958B1 (en) 2002-06-14 2011-08-10 Gen-Probe Incorporated Compositions for detecting hepatitis b virus
WO2004031729A2 (en) * 2002-10-01 2004-04-15 Georgetown University Diagnostic for long term response of hbv carrier to 3tc therapy
WO2006097284A1 (en) 2005-03-15 2006-09-21 Rheinische Friedrich-Wilhelms-Universität Bonn Variants of hepatitis b virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof
PL1858916T4 (pl) 2005-03-15 2015-04-30 Fujirebio Europe N V Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie
JP2008534020A (ja) 2005-04-08 2008-08-28 メルボルン ヘルス 抗ウイルス性のヌクレオシド剤に耐性を示すｂ型肝炎ウイルスのバリアントおよびその応用法
AU2006230802A1 (en) 2005-04-08 2006-10-12 Austin Health Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof
KR100790226B1 (ko) 2005-11-03 2008-01-02 연세대학교 산학협력단 독성 간염 유발 감수성을 검출하는 방법
CN102317473A (zh) * 2008-12-11 2012-01-11 加利福尼亚太平洋生物科学股份有限公司 核酸模板的分类
US12527665B2 (en) 2008-12-11 2026-01-20 Pacific Biosciences Of California, Inc. Methods for identifying modified bases in nucleic acid templates
US9175338B2 (en) 2008-12-11 2015-11-03 Pacific Biosciences Of California, Inc. Methods for identifying nucleic acid modifications
EP2694686B2 (en) 2011-04-06 2023-07-19 The University of Chicago COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-METHYLCYTOSINE (5mC)
US9238836B2 (en) 2012-03-30 2016-01-19 Pacific Biosciences Of California, Inc. Methods and compositions for sequencing modified nucleic acids
US9175348B2 (en) 2012-04-24 2015-11-03 Pacific Biosciences Of California, Inc. Identification of 5-methyl-C in nucleic acid templates
US20230242590A1 (en) * 2019-12-07 2023-08-03 Isa Pharmaceuticals B.V. Treatment of diseases related to hepatitis b virus
TWI867312B (zh) * 2021-07-01 2024-12-21 國立成功大學 體外定量b肝病毒大表面蛋白的套組，用於分析hbv感染階段及肝癌預後的生物指標組，以及用於預測、診斷或治療慢性肝病的單株抗體組

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595739A (en) * 1993-05-07 1997-01-21 Abbott Laboratories Hepatitis B virus mutants, reagents and methods for detection
ZA973367B (en) * 1996-04-19 1997-11-18 Innogenetics Nv Method for typing and detecting HBV.
AUPO351996A0 (en) * 1996-11-08 1996-12-05 Western Health Care Network Viral variants and methods for detecting same
USRE40233E1 (en) * 1996-11-08 2008-04-08 Melbourne Health Viral variants and methods for detecting same
AUPP967999A0 (en) * 1999-04-09 1999-05-06 North Western Health Care Network Viral variants
AUPQ810900A0 (en) * 2000-06-09 2000-07-06 Austin and Repatriation Medical Centre, The Viral variants and methods of using same
US7405039B2 (en) * 2002-02-07 2008-07-29 Austin Health Viral variants with altered susceptibility to nucleoside analogs and uses thereof
TR200402517T1 (tr) * 2002-03-29 2007-12-24 Innogenetics N.V. HBV ilaç direnci tespit metotları
EP2033967A1 (en) * 2002-04-12 2009-03-11 Melbourne Health Hepatitis B viral variants with reduced susceptibility to nucleoside analogs and uses thereof
EP1692278B1 (en) * 2003-10-21 2013-07-03 Melbourne Health Hbv variants detection and application
PL1858916T4 (pl) * 2005-03-15 2015-04-30 Fujirebio Europe N V Warianty wirusa zapalenia wątroby typu b z obniżoną wrażliwością na analogi nukleozydów i ich zastosowanie
WO2006097284A1 (en) * 2005-03-15 2006-09-21 Rheinische Friedrich-Wilhelms-Universität Bonn Variants of hepatitis b virus resistant against some nucleoside analogues, but sensitive to others, and uses thereof
AU2006230802A1 (en) * 2005-04-08 2006-10-12 Austin Health Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof
JP2008534020A (ja) * 2005-04-08 2008-08-28 メルボルン ヘルス 抗ウイルス性のヌクレオシド剤に耐性を示すｂ型肝炎ウイルスのバリアントおよびその応用法
CN101548014B (zh) * 2006-06-06 2012-07-04 墨尔本保健公司 抗病毒抗性突变的检测和应用

Also Published As

Publication number Publication date
JP2008154590A (ja) 2008-07-10
AUPO351996A0 (en) 1996-12-05
ES2279542T3 (es) 2007-08-16
JP2015107127A (ja) 2015-06-11
HK1027374A1 (en) 2001-01-12
US6555311B1 (en) 2003-04-29
JP2012055322A (ja) 2012-03-22
DE69737126D1 (de) 2007-02-01
CA2270178C (en) 2012-06-12
EP0964916A4 (en) 2001-09-26
JP2001503277A (ja) 2001-03-13
US20130171620A1 (en) 2013-07-04
US20100203506A1 (en) 2010-08-12
WO1998021317A1 (en) 1998-05-22
EP0964916A1 (en) 1999-12-22
EP0964916B1 (en) 2006-12-20
DE69737126T2 (de) 2007-10-04
US20030124096A1 (en) 2003-07-03
CA2270178A1 (en) 1998-05-22

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