ATE347599T1 - Tuberkulose impfstoff - Google Patents
Tuberkulose impfstoffInfo
- Publication number
- ATE347599T1 ATE347599T1 AT98947427T AT98947427T ATE347599T1 AT E347599 T1 ATE347599 T1 AT E347599T1 AT 98947427 T AT98947427 T AT 98947427T AT 98947427 T AT98947427 T AT 98947427T AT E347599 T1 ATE347599 T1 AT E347599T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- acid molecules
- present
- tuberculosis vaccine
- novel recombinant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97114614A EP0902086A1 (de) | 1997-08-22 | 1997-08-22 | Tuberkolose Impfstoff |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE347599T1 true ATE347599T1 (de) | 2006-12-15 |
Family
ID=8227261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98947427T ATE347599T1 (de) | 1997-08-22 | 1998-08-12 | Tuberkulose impfstoff |
Country Status (13)
Country | Link |
---|---|
US (1) | US6673353B1 (de) |
EP (2) | EP0902086A1 (de) |
JP (1) | JP4255209B2 (de) |
AT (1) | ATE347599T1 (de) |
AU (1) | AU9435098A (de) |
CA (1) | CA2301879C (de) |
CY (1) | CY1106350T1 (de) |
DE (1) | DE69836588T2 (de) |
DK (1) | DK1007686T3 (de) |
ES (1) | ES2274580T3 (de) |
PT (1) | PT1007686E (de) |
SI (1) | SI1007686T1 (de) |
WO (1) | WO1999010496A1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6051237A (en) | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
US7820180B2 (en) | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
US8114414B2 (en) | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
US8956621B2 (en) | 1994-11-08 | 2015-02-17 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical dysplasia |
US7794729B2 (en) | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
US7662396B2 (en) | 2001-03-26 | 2010-02-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
EP1144447B1 (de) | 1998-11-04 | 2009-10-14 | Isis Innovation Limited | Tuberkulose diagnose test |
GB0006693D0 (en) * | 2000-03-20 | 2000-05-10 | Glaxo Group Ltd | Vaccine |
US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
US6855320B2 (en) | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
AU2001255196A1 (en) | 2000-03-29 | 2001-10-08 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing immunogenicity of antigens |
US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
US7700344B2 (en) | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
CA2515369C (en) * | 2003-02-06 | 2015-03-31 | Cerus Corporation | Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the listeria, and methods of use thereof |
BRPI0409789B8 (pt) * | 2003-04-23 | 2021-05-25 | Max Planck Gesellschaft | célula bacteriana, seus processos de preparação e seu uso, composição, e processo para a preparação de uma vacina viva |
EP1649869A1 (de) * | 2004-10-21 | 2006-04-26 | Vakzine Projekt Management GmbH | Kombination von rekombinanten Mycobakterien und einem biologisch aktiven Agent als Vakzine |
AU2005338353B2 (en) * | 2004-12-01 | 2011-04-14 | Aeras Global Tb Vaccine Foundation | Recombinant BCG strains with enhanced ability to escape the endosome |
ES2657168T3 (es) | 2006-08-15 | 2018-03-01 | The Trustees Of The University Of Pennsylvania | Composiciones que comprenden HMW-MAA y fragmentos de este para el tratamiento del cáncer |
US8268326B2 (en) | 2006-08-15 | 2012-09-18 | The Trustees Of The University Of Pennsylvania | Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof |
EP2288379A4 (de) | 2008-05-19 | 2012-08-08 | Advaxis | Doppeltes freisetzungssystem für heterologe antigene |
US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
DK2403935T3 (en) | 2009-03-04 | 2017-09-11 | Univ Pennsylvania | COMPOSITIONS CONTAINING ANGIOGENIC FACTORS AND METHODS OF USE THEREOF |
US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
HUE048774T2 (hu) * | 2010-09-20 | 2020-08-28 | Vakzine Projekt Man Gmbh | Rekombináns Mycobacterium vakcinaként embereken történõ alkalmazásra |
JP5981436B2 (ja) | 2010-10-01 | 2016-08-31 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 寄生的に感染している対象におけるワクチン不応答性を反転させるためのリステリアワクチンベクターの使用 |
EA029833B9 (ru) | 2010-12-21 | 2018-06-29 | Макс-Планк-Гезельшафт Цур Фёрдерунг Дер Виссеншафтен Е.В. | Способ определения эффективности против микобактериальных инфекций рекомбинантной живой вакцины и варианты набора реагентов для его осуществления |
BR112013015882B8 (pt) * | 2010-12-21 | 2021-01-05 | Max Planck Gesellschaft | célula recombinante de mycobacterium bovis (m. bovis) do bacillus calmette-guérin (bcg) da cepa danish subtipo prague e uso da mesma |
CA2829960A1 (en) | 2011-03-11 | 2012-09-20 | John Rothman | Listeria-based adjuvants |
BR102012003790A2 (pt) | 2012-02-17 | 2014-04-22 | Fundacao Butantan | Cepa de mycobacterium recombinante, composição imunogênica e uso |
BR112014022662A2 (pt) | 2012-03-12 | 2017-10-03 | Advaxis Inc | Inibição da função de célula supressora seguindo tratamento de vacina de listeria |
EP2834356A4 (de) * | 2012-04-02 | 2015-09-02 | Univ Arizona | Rekombinantes bakterium zur induktion einer zellulären immunantwort |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5504005A (en) * | 1987-03-02 | 1996-04-02 | Albert Einstein College Of Medicine Of Yeshiva University | Recombinant mycobacterial vaccine |
-
1997
- 1997-08-22 EP EP97114614A patent/EP0902086A1/de not_active Withdrawn
-
1998
- 1998-08-12 AT AT98947427T patent/ATE347599T1/de active
- 1998-08-12 SI SI9830871T patent/SI1007686T1/sl unknown
- 1998-08-12 JP JP2000507804A patent/JP4255209B2/ja not_active Expired - Lifetime
- 1998-08-12 DE DE69836588T patent/DE69836588T2/de not_active Expired - Lifetime
- 1998-08-12 CA CA2301879A patent/CA2301879C/en not_active Expired - Lifetime
- 1998-08-12 AU AU94350/98A patent/AU9435098A/en not_active Abandoned
- 1998-08-12 DK DK98947427T patent/DK1007686T3/da active
- 1998-08-12 WO PCT/EP1998/005109 patent/WO1999010496A1/en active IP Right Grant
- 1998-08-12 US US09/485,717 patent/US6673353B1/en not_active Expired - Lifetime
- 1998-08-12 EP EP98947427A patent/EP1007686B1/de not_active Expired - Lifetime
- 1998-08-12 PT PT98947427T patent/PT1007686E/pt unknown
- 1998-08-12 ES ES98947427T patent/ES2274580T3/es not_active Expired - Lifetime
-
2007
- 2007-03-01 CY CY20071100297T patent/CY1106350T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2274580T3 (es) | 2007-05-16 |
PT1007686E (pt) | 2007-03-30 |
CA2301879C (en) | 2014-02-04 |
US6673353B1 (en) | 2004-01-06 |
EP0902086A1 (de) | 1999-03-17 |
DE69836588D1 (de) | 2007-01-18 |
WO1999010496A1 (en) | 1999-03-04 |
CY1106350T1 (el) | 2011-10-12 |
CA2301879A1 (en) | 1999-03-04 |
JP4255209B2 (ja) | 2009-04-15 |
EP1007686B1 (de) | 2006-12-06 |
DE69836588T2 (de) | 2007-04-05 |
AU9435098A (en) | 1999-03-16 |
JP2001514000A (ja) | 2001-09-11 |
DK1007686T3 (da) | 2007-04-10 |
SI1007686T1 (sl) | 2007-04-30 |
EP1007686A1 (de) | 2000-06-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
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