DK1007686T3 - Tuberkulosevaccine - Google Patents
TuberkulosevaccineInfo
- Publication number
- DK1007686T3 DK1007686T3 DK98947427T DK98947427T DK1007686T3 DK 1007686 T3 DK1007686 T3 DK 1007686T3 DK 98947427 T DK98947427 T DK 98947427T DK 98947427 T DK98947427 T DK 98947427T DK 1007686 T3 DK1007686 T3 DK 1007686T3
- Authority
- DK
- Denmark
- Prior art keywords
- nucleic acid
- acid molecules
- present
- tuberculosis vaccine
- novel recombinant
- Prior art date
Links
- 229960002109 tuberculosis vaccine Drugs 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 108010008038 Synthetic Vaccines Proteins 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229940124551 recombinant vaccine Drugs 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97114614A EP0902086A1 (en) | 1997-08-22 | 1997-08-22 | Tuberculosis vaccine |
| PCT/EP1998/005109 WO1999010496A1 (en) | 1997-08-22 | 1998-08-12 | Tuberculosis vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1007686T3 true DK1007686T3 (da) | 2007-04-10 |
Family
ID=8227261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98947427T DK1007686T3 (da) | 1997-08-22 | 1998-08-12 | Tuberkulosevaccine |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6673353B1 (da) |
| EP (2) | EP0902086A1 (da) |
| JP (1) | JP4255209B2 (da) |
| AT (1) | ATE347599T1 (da) |
| AU (1) | AU9435098A (da) |
| CA (1) | CA2301879C (da) |
| CY (1) | CY1106350T1 (da) |
| DE (1) | DE69836588T2 (da) |
| DK (1) | DK1007686T3 (da) |
| ES (1) | ES2274580T3 (da) |
| PT (1) | PT1007686E (da) |
| SI (1) | SI1007686T1 (da) |
| WO (1) | WO1999010496A1 (da) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7635479B2 (en) | 2000-03-29 | 2009-12-22 | The Trustees Of The University Of Pennsylvania | Composition and methods for enhancing immunogenecity of antigens |
| US8956621B2 (en) | 1994-11-08 | 2015-02-17 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical dysplasia |
| US8114414B2 (en) | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
| US6051237A (en) * | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
| US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
| US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US7662396B2 (en) | 2001-03-26 | 2010-02-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| US7794729B2 (en) | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
| AU6480999A (en) | 1998-11-04 | 2000-05-22 | Isis Innovation Limited | Tuberculosis diagnostic test |
| GB0006693D0 (en) * | 2000-03-20 | 2000-05-10 | Glaxo Group Ltd | Vaccine |
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| US6855320B2 (en) | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
| US8771702B2 (en) | 2001-03-26 | 2014-07-08 | The Trustees Of The University Of Pennsylvania | Non-hemolytic LLO fusion proteins and methods of utilizing same |
| US7700344B2 (en) | 2001-03-26 | 2010-04-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| KR101192652B1 (ko) * | 2003-02-06 | 2012-10-19 | 앤저 테라퓨틱스 인코퍼레이티드 | 비포식 세포로의 침투가 약화된 리스테리아, 리스테리아를 포함하는 백신, 및 그것의 사용방법 |
| JP4662925B2 (ja) * | 2003-04-23 | 2011-03-30 | マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ | 改善された効率を有する結核ワクチン |
| EP1649869A1 (en) * | 2004-10-21 | 2006-04-26 | Vakzine Projekt Management GmbH | Combination of a recombinant mycobacterium and a biologically active agent as a vaccine |
| EP1827504B1 (en) * | 2004-12-01 | 2011-05-11 | Aeras Global TB Vaccine Foundation | Recombinant bcg strains with enhanced ability to escape the endosome |
| WO2008079172A2 (en) | 2006-08-15 | 2008-07-03 | The Trustees Of The University Of Pennsylvania | Compositions comprising hmw-maa and fragments thereof, and methods of use thereof |
| US8268326B2 (en) | 2006-08-15 | 2012-09-18 | The Trustees Of The University Of Pennsylvania | Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof |
| EP2853269B1 (en) | 2008-05-19 | 2019-05-01 | Advaxis, Inc. | Dual delivery system for heterologous antigens comprising a recombinant Listeria strain attenuated by mutation of dal/dat and deletion of ActA comprising a nucleic acid molecule encoding an listeriolysin O - prostate specific anigen fusion protein |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| JP5539411B2 (ja) | 2009-03-04 | 2014-07-02 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 血管新生因子を含む組成物およびその使用方法 |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| CN103118703A (zh) | 2010-09-20 | 2013-05-22 | 疫苗项目管理有限公司 | 作为人用疫苗的重组分枝杆菌 |
| WO2012138377A2 (en) | 2010-10-01 | 2012-10-11 | Trustees Of The University Of Pennsylvania | The use of listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals |
| DK2656070T3 (da) | 2010-12-21 | 2016-06-13 | Max-Planck-Gesellschaft Zur Förderung Der Wss E V | Bestemmelse af en levende rekombineret anti-mycobakteriel vaccinationseffektivitet |
| JP6006909B2 (ja) | 2010-12-21 | 2016-10-12 | マックス−プランク−ゲゼルシャフト ツール フェルデルンク デル ヴィッセンシャフテン エー．ファウ． | ワクチンとしての組み換えマイコバクテリウム |
| WO2012125551A1 (en) | 2011-03-11 | 2012-09-20 | Advaxis | Listeria-based adjuvants |
| BR102012003790A2 (pt) | 2012-02-17 | 2014-04-22 | Fundacao Butantan | Cepa de mycobacterium recombinante, composição imunogênica e uso |
| CN104411327A (zh) | 2012-03-12 | 2015-03-11 | 阿德瓦希斯公司 | 李斯特菌疫苗治疗以后的抑制细胞功能抑制 |
| EP2834356A4 (en) * | 2012-04-02 | 2015-09-02 | Univ Arizona | RECOMBINANT BACTERIUM FOR INDUCING A CELLULAR IMMUNE RESPONSE |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5504005A (en) * | 1987-03-02 | 1996-04-02 | Albert Einstein College Of Medicine Of Yeshiva University | Recombinant mycobacterial vaccine |
-
1997
- 1997-08-22 EP EP97114614A patent/EP0902086A1/en not_active Withdrawn
-
1998
- 1998-08-12 SI SI9830871T patent/SI1007686T1/sl unknown
- 1998-08-12 US US09/485,717 patent/US6673353B1/en not_active Expired - Lifetime
- 1998-08-12 AU AU94350/98A patent/AU9435098A/en not_active Abandoned
- 1998-08-12 DE DE69836588T patent/DE69836588T2/de not_active Expired - Lifetime
- 1998-08-12 PT PT98947427T patent/PT1007686E/pt unknown
- 1998-08-12 DK DK98947427T patent/DK1007686T3/da active
- 1998-08-12 EP EP98947427A patent/EP1007686B1/en not_active Expired - Lifetime
- 1998-08-12 CA CA2301879A patent/CA2301879C/en not_active Expired - Lifetime
- 1998-08-12 AT AT98947427T patent/ATE347599T1/de active
- 1998-08-12 JP JP2000507804A patent/JP4255209B2/ja not_active Expired - Lifetime
- 1998-08-12 ES ES98947427T patent/ES2274580T3/es not_active Expired - Lifetime
- 1998-08-12 WO PCT/EP1998/005109 patent/WO1999010496A1/en active IP Right Grant
-
2007
- 2007-03-01 CY CY20071100297T patent/CY1106350T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6673353B1 (en) | 2004-01-06 |
| EP0902086A1 (en) | 1999-03-17 |
| PT1007686E (pt) | 2007-03-30 |
| DE69836588T2 (de) | 2007-04-05 |
| EP1007686A1 (en) | 2000-06-14 |
| ES2274580T3 (es) | 2007-05-16 |
| WO1999010496A1 (en) | 1999-03-04 |
| ATE347599T1 (de) | 2006-12-15 |
| CA2301879C (en) | 2014-02-04 |
| DE69836588D1 (de) | 2007-01-18 |
| JP4255209B2 (ja) | 2009-04-15 |
| AU9435098A (en) | 1999-03-16 |
| SI1007686T1 (sl) | 2007-04-30 |
| CA2301879A1 (en) | 1999-03-04 |
| JP2001514000A (ja) | 2001-09-11 |
| EP1007686B1 (en) | 2006-12-06 |
| CY1106350T1 (el) | 2011-10-12 |
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