ATE347546T1 - Hydroxyformamidin-derivate und diese enthaltende medikamente - Google Patents
Hydroxyformamidin-derivate und diese enthaltende medikamenteInfo
- Publication number
- ATE347546T1 ATE347546T1 AT01941061T AT01941061T ATE347546T1 AT E347546 T1 ATE347546 T1 AT E347546T1 AT 01941061 T AT01941061 T AT 01941061T AT 01941061 T AT01941061 T AT 01941061T AT E347546 T1 ATE347546 T1 AT E347546T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- formula
- substituted
- represented
- participates
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000006681 (C2-C10) alkylene group Chemical group 0.000 abstract 1
- NNDIXBJHNLFJJP-UHFFFAOYSA-N 20-Hydroxyeicosatetraenoic acid Chemical compound OCCCCCC=CCC=CCC=CCC=CCCCC(O)=O NNDIXBJHNLFJJP-UHFFFAOYSA-N 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 230000010339 dilation Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 210000004088 microvessel Anatomy 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000180479 | 2000-06-15 | ||
| JP2000180477 | 2000-06-15 | ||
| JP2000336140 | 2000-11-02 | ||
| JP2000359781 | 2000-11-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE347546T1 true ATE347546T1 (de) | 2006-12-15 |
Family
ID=27481364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01941061T ATE347546T1 (de) | 2000-06-15 | 2001-06-15 | Hydroxyformamidin-derivate und diese enthaltende medikamente |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6670382B2 (de) |
| EP (1) | EP1291343B1 (de) |
| JP (1) | JP4904659B2 (de) |
| KR (1) | KR100776095B1 (de) |
| CN (1) | CN1177824C (de) |
| AT (1) | ATE347546T1 (de) |
| AU (2) | AU2001274535B2 (de) |
| CA (1) | CA2411418C (de) |
| DE (1) | DE60125036T2 (de) |
| DK (1) | DK1291343T3 (de) |
| ES (1) | ES2280379T3 (de) |
| HK (1) | HK1057043A1 (de) |
| WO (1) | WO2001096309A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100776095B1 (ko) | 2000-06-15 | 2007-11-15 | 다이쇼 세이야꾸 가부시끼가이샤 | 히드록시포름아미딘 유도체 및 이들을 포함하는 의약 |
| JP4120401B2 (ja) | 2001-04-26 | 2008-07-16 | 大正製薬株式会社 | ２０−ヒドロキシエイコサテトラエン酸産生阻害剤 |
| DE60218152T2 (de) * | 2001-05-02 | 2007-12-06 | Symbian Ltd. | Gruppenkommunikationsverfahren für ein funkkommunikationsgerät |
| WO2003022821A1 (fr) * | 2001-09-06 | 2003-03-20 | Taisho Pharmaceutical Co., Ltd. | Derive d'heterocycle presentant une activite inhibitrice de l'enzyme de production du 20-hete |
| AU2003262069A1 (en) | 2002-09-12 | 2004-04-30 | Taisho Pharmaceutical Co., Ltd. | N-hydroxyformamidine derivative |
| ES2814200T3 (es) | 2005-07-29 | 2021-03-26 | Basf Se | Estabilización de productos para el cuidado del cuerpo y del hogar contra la degradación por radiación UV utilizando derivados de merocianina |
| UA102514C2 (ru) * | 2007-02-22 | 2013-07-25 | Сингента Партисипейшнс Аг | Производные иминопиридина, промежуточное соединение, способ борьбы с заражением полезных растений грибами или его предупреждение и композиция на основе производной иминопиридина |
| KR20180109871A (ko) * | 2016-02-15 | 2018-10-08 | 다이쇼 세이야꾸 가부시끼가이샤 | 아졸로 치환된 피리딘 화합물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3998970A (en) | 1975-04-28 | 1976-12-21 | Stauffer Chemical Company | N,N-dimethyl-N'-phenylthiocarbamyl formamidine and its use as an anti-inflammatory agent |
| US3959368A (en) | 1975-04-28 | 1976-05-25 | Stauffer Chemical Company | N,N-dimethyl-N'-phenylthiocarbamyl formamidine and its use as an anti-inflammatory agent |
| GB1594261A (en) | 1977-02-18 | 1981-07-30 | Shell Int Research | Benzyloxime ethers |
| US4079149A (en) | 1977-06-30 | 1978-03-14 | Shell Oil Company | Benzyl oxime ethers |
| IL56878A (en) | 1978-03-31 | 1984-03-30 | Rhone Poulenc Inc | Ketoximinoethers and their use as insecticides |
| US4158015A (en) | 1978-08-16 | 1979-06-12 | Mobil Oil Corporation | Process for the stereoselective synthesis of the E isomer of aryl alkyl oximes |
| DE2907972A1 (de) | 1979-03-01 | 1980-09-11 | Bayer Ag | Omega -halogen-acetophenon-oximether, verfahren zu ihrer herstellung sowie ihre verwendung als zwischenprodukte zur herstellung von omega -azolyl-acetophenon-oximethern |
| IL60884A0 (en) | 1979-08-24 | 1980-10-26 | Mobil Oil Corp | Ketoximinoethers and their use as insecticides |
| DE3005899A1 (de) | 1980-02-16 | 1981-09-03 | Hoechst Ag, 6000 Frankfurt | Derivate des 1,2,4-triazols und imidazols, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel |
| DE3044564A1 (de) | 1980-11-26 | 1982-07-15 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von (alpha)-bromacetophenonoximethern |
| US4474815A (en) | 1981-04-30 | 1984-10-02 | Commonwealth Scientific And Industrial Research Organization | Insecticidal oximes |
| US4566901A (en) | 1982-05-06 | 1986-01-28 | Ciba-Geigy Corporation | Novel oxime ethers, the preparation thereof, compositions containing them and the use thereof |
| US4434182A (en) | 1982-11-01 | 1984-02-28 | Fmc Corporation | Insecticidal substituted-biphenylmethyl oxime ethers |
| IL75858A (en) | 1984-07-31 | 1989-02-28 | Commw Scient Ind Res Org | Substituted benzyl ethers of oximes,their production and their use as arthropodicides |
| US4824476A (en) | 1985-06-24 | 1989-04-25 | Ciba-Geigy Corporation | Herbicidally active derivatives of N-phenyl-3,4,5,6-tetrahydrophthalimide |
| DE4213149A1 (de) | 1992-04-22 | 1993-10-28 | Hoechst Ag | Akarizide, insektizide und nematizide substituierte (Hetero)-Aryl-Alkyl-ketonoxim-O-ether, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel |
| US5267857A (en) | 1993-02-12 | 1993-12-07 | A-Dec, Inc. | Brightness control system for dental handpiece light |
| DK1226819T3 (da) * | 1999-11-01 | 2006-05-22 | Taisho Pharmaceutical Co Ltd | Inhibitor for 20-HETE-producerende enzym |
| KR100776095B1 (ko) | 2000-06-15 | 2007-11-15 | 다이쇼 세이야꾸 가부시끼가이샤 | 히드록시포름아미딘 유도체 및 이들을 포함하는 의약 |
| JP4120401B2 (ja) * | 2001-04-26 | 2008-07-16 | 大正製薬株式会社 | ２０−ヒドロキシエイコサテトラエン酸産生阻害剤 |
-
2001
- 2001-06-15 KR KR1020027016921A patent/KR100776095B1/ko not_active IP Right Cessation
- 2001-06-15 US US10/311,003 patent/US6670382B2/en not_active Expired - Fee Related
- 2001-06-15 CN CNB018110126A patent/CN1177824C/zh not_active Expired - Fee Related
- 2001-06-15 EP EP01941061A patent/EP1291343B1/de not_active Expired - Lifetime
- 2001-06-15 AU AU2001274535A patent/AU2001274535B2/en not_active Ceased
- 2001-06-15 DE DE60125036T patent/DE60125036T2/de not_active Expired - Lifetime
- 2001-06-15 ES ES01941061T patent/ES2280379T3/es not_active Expired - Lifetime
- 2001-06-15 AU AU7453501A patent/AU7453501A/xx active Pending
- 2001-06-15 DK DK01941061T patent/DK1291343T3/da active
- 2001-06-15 AT AT01941061T patent/ATE347546T1/de active
- 2001-06-15 JP JP2002510452A patent/JP4904659B2/ja not_active Expired - Fee Related
- 2001-06-15 WO PCT/JP2001/005108 patent/WO2001096309A1/ja active IP Right Grant
- 2001-06-15 CA CA002411418A patent/CA2411418C/en not_active Expired - Fee Related
-
2003
- 2003-12-23 HK HK03109324A patent/HK1057043A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP4904659B2 (ja) | 2012-03-28 |
| KR100776095B1 (ko) | 2007-11-15 |
| HK1057043A1 (en) | 2004-03-12 |
| ES2280379T3 (es) | 2007-09-16 |
| US20030186979A1 (en) | 2003-10-02 |
| CN1177824C (zh) | 2004-12-01 |
| KR20030010690A (ko) | 2003-02-05 |
| DE60125036D1 (de) | 2007-01-18 |
| CA2411418A1 (en) | 2002-12-06 |
| CA2411418C (en) | 2010-01-12 |
| EP1291343B1 (de) | 2006-12-06 |
| US6670382B2 (en) | 2003-12-30 |
| AU2001274535B2 (en) | 2005-06-30 |
| EP1291343A4 (de) | 2004-04-07 |
| CN1436173A (zh) | 2003-08-13 |
| EP1291343A1 (de) | 2003-03-12 |
| DK1291343T3 (da) | 2007-02-05 |
| AU7453501A (en) | 2001-12-24 |
| WO2001096309A1 (fr) | 2001-12-20 |
| DE60125036T2 (de) | 2007-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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