ATE334977T1 - Discodermolid-analoga und ihre pharmazeutische verwendung - Google Patents

Discodermolid-analoga und ihre pharmazeutische verwendung

Info

Publication number
ATE334977T1
ATE334977T1 AT02025728T AT02025728T ATE334977T1 AT E334977 T1 ATE334977 T1 AT E334977T1 AT 02025728 T AT02025728 T AT 02025728T AT 02025728 T AT02025728 T AT 02025728T AT E334977 T1 ATE334977 T1 AT E334977T1
Authority
AT
Austria
Prior art keywords
pharmaceutical use
discodermolide
analogues
discodermolide analogues
compounds
Prior art date
Application number
AT02025728T
Other languages
German (de)
English (en)
Inventor
Kenneth Walter Bair
Jr Frederick Ray Kinder
Timothy Michael Ramsey
Michael Lloyd Sabio
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE334977T1 publication Critical patent/ATE334977T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pyrane Compounds (AREA)
AT02025728T 2001-11-16 2002-11-15 Discodermolid-analoga und ihre pharmazeutische verwendung ATE334977T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33239901P 2001-11-16 2001-11-16
US34339401P 2001-12-21 2001-12-21

Publications (1)

Publication Number Publication Date
ATE334977T1 true ATE334977T1 (de) 2006-08-15

Family

ID=26988201

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02025728T ATE334977T1 (de) 2001-11-16 2002-11-15 Discodermolid-analoga und ihre pharmazeutische verwendung

Country Status (9)

Country Link
US (2) US6833367B2 (cg-RX-API-DMAC7.html)
EP (1) EP1312608B1 (cg-RX-API-DMAC7.html)
JP (1) JP4410986B2 (cg-RX-API-DMAC7.html)
AT (1) ATE334977T1 (cg-RX-API-DMAC7.html)
CY (1) CY1106201T1 (cg-RX-API-DMAC7.html)
DE (1) DE60213541T2 (cg-RX-API-DMAC7.html)
DK (1) DK1312608T3 (cg-RX-API-DMAC7.html)
ES (1) ES2267928T3 (cg-RX-API-DMAC7.html)
PT (1) PT1312608E (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7348436B2 (en) * 2004-03-02 2008-03-25 Kosan Biosciences Incorporated Compounds useful for the synthesis of (+)-discodermolide and methods thereof
US7214708B2 (en) * 2004-11-18 2007-05-08 Kosan Biosciences Incorporated Synthetic discodermolide analogs
FR2951720B1 (fr) * 2009-10-28 2011-12-16 Pf Medicament Molecules polyketides comme agents anticancereux
EP2588474A4 (en) * 2010-07-01 2014-07-23 Yuhan Corp PROCESS FOR THE PREPARATION OF HMG-COA REDUCTASE INHIBITORS AND INTERMEDIATE PRODUCTS THEREOF

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5010099A (en) * 1989-08-11 1991-04-23 Harbor Branch Oceanographic Institution, Inc. Discodermolide compounds, compositions containing same and method of preparation and use
US5681847A (en) * 1995-12-05 1997-10-28 Harbor Branch Oceanographic Institution, Inc. Methods of using discodermolide compounds
US6242616B1 (en) * 1996-12-03 2001-06-05 The Trustees Of The University Of Pennsylvania Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives
US6096904A (en) * 1996-12-03 2000-08-01 The Trustees Of The University Of Pennsylvania Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives
US5789605A (en) 1996-12-03 1998-08-04 Trustees Of The University Of Pennsylvania Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof
US6870058B2 (en) 1996-12-03 2005-03-22 The Trustees Of The University Of Pennsylvania Compounds which mimic the chemical and biological properties of discodermolide
US6127406A (en) * 1998-10-09 2000-10-03 Harbor Branch Oceanographic Institution, Inc. Discodermolide compounds and methods of use
AU2001247241A1 (en) * 2000-03-01 2001-09-12 Harbor Branch Oceanographic Institution, Inc. Biologically active analogs of discodermolide

Also Published As

Publication number Publication date
DK1312608T3 (da) 2006-11-27
JP2003160575A (ja) 2003-06-03
EP1312608A2 (en) 2003-05-21
DE60213541T2 (de) 2007-10-04
US7148218B2 (en) 2006-12-12
JP4410986B2 (ja) 2010-02-10
EP1312608A3 (en) 2003-06-18
CY1106201T1 (el) 2011-06-08
US6833367B2 (en) 2004-12-21
ES2267928T3 (es) 2007-03-16
US20050080080A1 (en) 2005-04-14
DE60213541D1 (de) 2006-09-14
EP1312608B1 (en) 2006-08-02
PT1312608E (pt) 2006-12-29
US20030153601A1 (en) 2003-08-14

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