CY1106201T1 - Αναλογα δισκοδepμολιδης και η φαρμακευτικη τους χρηση - Google Patents

Αναλογα δισκοδepμολιδης και η φαρμακευτικη τους χρηση

Info

Publication number
CY1106201T1
CY1106201T1 CY20061101483T CY061101483T CY1106201T1 CY 1106201 T1 CY1106201 T1 CY 1106201T1 CY 20061101483 T CY20061101483 T CY 20061101483T CY 061101483 T CY061101483 T CY 061101483T CY 1106201 T1 CY1106201 T1 CY 1106201T1
Authority
CY
Cyprus
Prior art keywords
discodepmolide
analogues
pharmaceutical use
formula
specific
Prior art date
Application number
CY20061101483T
Other languages
English (en)
Inventor
Kenneth Walter Bair
Frederick Ray KINDER JR.
Timothy Michael Ramsey
Michael Lloyd Sabio
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1106201T1 publication Critical patent/CY1106201T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Η παρούσα εφεύρεση αφορά συγκεκριμένα ανάλογα δισκοδερμολίδης της φόρμουλας I
CY20061101483T 2001-11-16 2006-10-16 Αναλογα δισκοδepμολιδης και η φαρμακευτικη τους χρηση CY1106201T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33239901P 2001-11-16 2001-11-16
US34339401P 2001-12-21 2001-12-21

Publications (1)

Publication Number Publication Date
CY1106201T1 true CY1106201T1 (el) 2011-06-08

Family

ID=26988201

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101483T CY1106201T1 (el) 2001-11-16 2006-10-16 Αναλογα δισκοδepμολιδης και η φαρμακευτικη τους χρηση

Country Status (9)

Country Link
US (2) US6833367B2 (el)
EP (1) EP1312608B1 (el)
JP (1) JP4410986B2 (el)
AT (1) ATE334977T1 (el)
CY (1) CY1106201T1 (el)
DE (1) DE60213541T2 (el)
DK (1) DK1312608T3 (el)
ES (1) ES2267928T3 (el)
PT (1) PT1312608E (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005084349A2 (en) * 2004-03-02 2005-09-15 Kosan Biosciences, Inc. Compounds useful for the synthesis of (+)-discodermolide and methods therefor
US7214708B2 (en) * 2004-11-18 2007-05-08 Kosan Biosciences Incorporated Synthetic discodermolide analogs
FR2951720B1 (fr) * 2009-10-28 2011-12-16 Pf Medicament Molecules polyketides comme agents anticancereux
CN105153010B (zh) * 2010-07-01 2018-06-08 柳韩洋行 HMG-CoA还原酶抑制剂及其中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5010099A (en) * 1989-08-11 1991-04-23 Harbor Branch Oceanographic Institution, Inc. Discodermolide compounds, compositions containing same and method of preparation and use
US5681847A (en) * 1995-12-05 1997-10-28 Harbor Branch Oceanographic Institution, Inc. Methods of using discodermolide compounds
US5789605A (en) 1996-12-03 1998-08-04 Trustees Of The University Of Pennsylvania Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof
US6870058B2 (en) 1996-12-03 2005-03-22 The Trustees Of The University Of Pennsylvania Compounds which mimic the chemical and biological properties of discodermolide
US6242616B1 (en) 1996-12-03 2001-06-05 The Trustees Of The University Of Pennsylvania Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives
US6096904A (en) * 1996-12-03 2000-08-01 The Trustees Of The University Of Pennsylvania Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives
US6127406A (en) * 1998-10-09 2000-10-03 Harbor Branch Oceanographic Institution, Inc. Discodermolide compounds and methods of use
WO2001064663A2 (en) * 2000-03-01 2001-09-07 Harbor Branch Oceanographic Institution, Inc. Biologically active analogs of discodermolide

Also Published As

Publication number Publication date
US7148218B2 (en) 2006-12-12
US20030153601A1 (en) 2003-08-14
ATE334977T1 (de) 2006-08-15
JP4410986B2 (ja) 2010-02-10
EP1312608B1 (en) 2006-08-02
DE60213541D1 (de) 2006-09-14
PT1312608E (pt) 2006-12-29
US6833367B2 (en) 2004-12-21
EP1312608A3 (en) 2003-06-18
US20050080080A1 (en) 2005-04-14
ES2267928T3 (es) 2007-03-16
EP1312608A2 (en) 2003-05-21
DK1312608T3 (da) 2006-11-27
DE60213541T2 (de) 2007-10-04
JP2003160575A (ja) 2003-06-03

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