ATE329263T1 - Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha - Google Patents

Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha

Info

Publication number
ATE329263T1
ATE329263T1 AT99971513T AT99971513T ATE329263T1 AT E329263 T1 ATE329263 T1 AT E329263T1 AT 99971513 T AT99971513 T AT 99971513T AT 99971513 T AT99971513 T AT 99971513T AT E329263 T1 ATE329263 T1 AT E329263T1
Authority
AT
Austria
Prior art keywords
heavy chain
light chain
alpha
antibody
variable
Prior art date
Application number
AT99971513T
Other languages
German (de)
English (en)
Inventor
Jonathan L Miller
Original Assignee
Jonathan L Miller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jonathan L Miller filed Critical Jonathan L Miller
Application granted granted Critical
Publication of ATE329263T1 publication Critical patent/ATE329263T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT99971513T 1998-10-30 1999-10-29 Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha ATE329263T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10627598P 1998-10-30 1998-10-30

Publications (1)

Publication Number Publication Date
ATE329263T1 true ATE329263T1 (de) 2006-06-15

Family

ID=22310524

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99971513T ATE329263T1 (de) 1998-10-30 1999-10-29 Regionen variabler schwerer ketten und variabler leichter ketten von antikörpern für humanes blutplättchen-glykoprotein ib alpha

Country Status (8)

Country Link
EP (1) EP1051620B1 (enExample)
JP (1) JP2002529054A (enExample)
AT (1) ATE329263T1 (enExample)
AU (1) AU1458500A (enExample)
CA (1) CA2317808A1 (enExample)
DE (1) DE69931756T2 (enExample)
IL (1) IL137121A0 (enExample)
WO (1) WO2000026667A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918788D0 (en) 1999-08-10 1999-10-13 Leuven K U Res & Dev Antithrombotic effect of platelet glycoprotein 1b blocking monoclonal Fab fragments
DE10019967A1 (de) * 2000-04-20 2001-10-25 Fenning Biomed Gmbh Dr Antikörper gegen natives gp96, deren Herstellung und Verwendung
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7658924B2 (en) 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
WO2004003144A2 (en) 2002-07-01 2004-01-08 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
EP1539236A4 (en) * 2002-07-03 2007-07-18 Univ Pennsylvania COMPOSITIONS, METHODS, AND KITS RELATED TO ANTI-BLOOD PLAYBACK AUTOANTIC BODIES AND INHIBITORS THEREOF
AU2003298112A1 (en) * 2002-11-13 2004-06-03 Micromet Ag Method for identifying antigen specific b cells
RU2006102570A (ru) * 2003-06-30 2007-08-20 Био-Текнолоджи Дженерал(Израиль) Лтд. (IL) Антитела и их применение
EP1749536A1 (en) * 2005-08-03 2007-02-07 Thrombotargets Europe, S.L. Activated factor X stimulants as new antihemorrhagic agents for topical use
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
EP2186829B1 (en) * 2008-11-14 2014-12-31 Canadian Blood Services Antibodies against GPIbalpha
CN102905727B (zh) * 2009-10-30 2016-12-07 詹森生物科技公司 Il-17a拮抗剂
KR20220127250A (ko) * 2019-12-10 2022-09-19 씨씨오에이 테라퓨틱스 (항저우) 컴퍼니 리미티드 인간화 항-당단백질 ib알파(gpibalpha) 항체
US20230055143A1 (en) * 2019-12-20 2023-02-23 Medimmune, Llc Compositions and Methods of Treating Cancer with Chimeric Antigen Receptors Targeting Glypican 3
WO2021262880A2 (en) * 2020-06-23 2021-12-30 Kadmon Corporation, Llc Anti-pd-1 antibodies and fusion proteins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877155A (en) * 1995-03-17 1999-03-02 The Research Foundation Of State University Of New York Mimotopes and anti-mimotopes of human platelet glycoprotein Ib/IX
US5817748A (en) * 1995-03-17 1998-10-06 The Research Foundation Of State University Of New York Mimotopes of human Platelet glycoprotein Ib/IX

Also Published As

Publication number Publication date
WO2000026667A1 (en) 2000-05-11
EP1051620A1 (en) 2000-11-15
JP2002529054A (ja) 2002-09-10
WO2000026667A9 (en) 2001-04-12
AU1458500A (en) 2000-05-22
CA2317808A1 (en) 2000-05-11
DE69931756T2 (de) 2007-05-24
DE69931756D1 (de) 2006-07-20
IL137121A0 (en) 2001-06-14
EP1051620A4 (en) 2005-01-12
EP1051620B1 (en) 2006-06-07

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