ATE324374T1 - Purinderivate und deren verwendung als antiproliferative mittel - Google Patents
Purinderivate und deren verwendung als antiproliferative mittelInfo
- Publication number
- ATE324374T1 ATE324374T1 AT03787886T AT03787886T ATE324374T1 AT E324374 T1 ATE324374 T1 AT E324374T1 AT 03787886 T AT03787886 T AT 03787886T AT 03787886 T AT03787886 T AT 03787886T AT E324374 T1 ATE324374 T1 AT E324374T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- disorders
- unbranched
- branched
- independently
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hospice & Palliative Care (AREA)
- AIDS & HIV (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0219052.8A GB0219052D0 (en) | 2002-08-15 | 2002-08-15 | New puring derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE324374T1 true ATE324374T1 (de) | 2006-05-15 |
Family
ID=9942406
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03787886T ATE324374T1 (de) | 2002-08-15 | 2003-08-13 | Purinderivate und deren verwendung als antiproliferative mittel |
Country Status (14)
Country | Link |
---|---|
US (2) | US7544689B2 (de) |
EP (1) | EP1534708B1 (de) |
JP (1) | JP4787495B2 (de) |
CN (1) | CN1312152C (de) |
AT (1) | ATE324374T1 (de) |
AU (1) | AU2003251063B2 (de) |
BR (2) | BR0313480A (de) |
CA (1) | CA2488834C (de) |
DE (1) | DE60304871T2 (de) |
GB (2) | GB0219052D0 (de) |
IL (1) | IL166783A (de) |
MX (1) | MXPA05001842A (de) |
NZ (1) | NZ538136A (de) |
WO (1) | WO2004016613A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2741881B1 (fr) * | 1995-12-01 | 1999-07-30 | Centre Nat Rech Scient | Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques |
GB0012528D0 (en) * | 2000-05-23 | 2000-07-12 | Univ Palackeho | Triterpenoid derivatives |
GB2378180B8 (en) * | 2001-06-27 | 2009-10-21 | Cyclacel Ltd | New purine derivatives |
GB0219054D0 (en) * | 2002-08-15 | 2002-09-25 | Cyclacel Ltd | New purine derivatives |
GB0219052D0 (en) * | 2002-08-15 | 2002-09-25 | Cyclacel Ltd | New puring derivatives |
AU2005276231A1 (en) | 2004-08-27 | 2006-03-02 | Cyclacel Limited | Purine and pyrimidine CDK inhibitors and their use for the treatment of autoimmune diseases |
GB0606283D0 (en) * | 2006-03-29 | 2006-05-10 | Cyclacel Ltd | Process |
MX2008014750A (es) | 2006-05-19 | 2009-02-04 | Topigen Pharmaceuticals Inc | Oligonucleotidos que afectan la expresion de fosfodiesterasas. |
GB0706632D0 (en) * | 2007-04-04 | 2007-05-16 | Cyclacel Ltd | New purine derivatives |
CZ302122B6 (cs) * | 2009-01-28 | 2010-10-20 | Univerzita Palackého v Olomouci | Substituované deriváty 6-(2-aminobenzylamino)purinu, jejich použití jako léciva a prípravky tyto slouceniny obsahující |
WO2011071491A1 (en) * | 2009-12-09 | 2011-06-16 | Signal Pharmaceuticals, Llc | Isotopologues of 4-[9-(tetrahydro-furan-3-yl)-8-(2, 4, 6- trifluoro-phenylamino)-9h-purin-2-ylamino]-cyclohexan-1-ol |
GB201001075D0 (en) | 2010-01-22 | 2010-03-10 | Cyclacel Ltd | Crystalline forms |
WO2013059634A1 (en) | 2011-10-20 | 2013-04-25 | The Regents Of The University Of California | Use of cdk9 inhibitors to reduce cartilage degradation |
WO2016061144A1 (en) | 2014-10-14 | 2016-04-21 | The Regents Of The University Of California | Use of cdk9 and brd4 inhibitors to inhibit inflammation |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2164271A (en) * | 1937-08-13 | 1939-06-27 | Purdue Research Foundation | Secondary aminoalcohols |
CH270828A (de) * | 1946-12-23 | 1950-09-30 | Limited Polymerisable Products | Verfahren zur Herstellung eines Aminoalkohols. |
WO1990009178A1 (en) | 1989-01-31 | 1990-08-23 | Whitby Research, Inc. | N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists |
GB9204015D0 (en) | 1992-02-25 | 1992-04-08 | Wellcome Found | Therapeutic nucleosides |
US5688774A (en) | 1993-07-13 | 1997-11-18 | The United States Of America As Represented By The Department Of Health And Human Services | A3 adenosine receptor agonists |
JP3396924B2 (ja) | 1993-09-07 | 2003-04-14 | 日本曹達株式会社 | 活性汚泥のバルキング防止剤 |
DE69513313T2 (de) | 1994-02-01 | 2000-07-13 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von Nukleinsäurebasenderivaten |
US5994361A (en) | 1994-06-22 | 1999-11-30 | Biochem Pharma | Substituted purinyl derivatives with immunomodulating activity |
ES2196181T3 (es) | 1995-11-01 | 2003-12-16 | Novartis Ag | Derivados de purina y proceso para su preparacion. |
FR2741881B1 (fr) | 1995-12-01 | 1999-07-30 | Centre Nat Rech Scient | Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques |
US6790958B2 (en) | 1996-08-02 | 2004-09-14 | Robert T. Lum | Purine inhibitors of cyclin dependent kinase 2 & IKBA |
US5866702A (en) * | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
AU4920397A (en) | 1996-10-11 | 1998-05-11 | Chiron Corporation | Purine inhibitors of glycogen synthase kinase 3 (gsk3) |
US6255485B1 (en) | 1997-08-07 | 2001-07-03 | The Regents Of The University Of California | Purine inhibitors of protein kinases, G proteins and polymerases |
US6573044B1 (en) | 1997-08-07 | 2003-06-03 | The Regents Of The University Of California | Methods of using chemical libraries to search for new kinase inhibitors |
WO1999034018A1 (en) | 1997-12-24 | 1999-07-08 | The Regents Of The University Of California | Methods of using chemical libraries to search for new kinase inhibitors |
PL344021A1 (en) | 1998-02-26 | 2001-09-24 | Aventis Pharma Inc | 6,9-disubstituted 2-[trans-(4- aminocyclohexyl) amino]purines |
CZ27399A3 (cs) | 1999-01-26 | 2000-08-16 | Ústav Experimentální Botaniky Av Čr | Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv |
ES2246829T3 (es) * | 1999-02-01 | 2006-03-01 | Cv Therapeutics Inc | Inhibidores purinicos de cinasa 2 y de ikb-alfa dependientes de ciclina. |
US6627633B2 (en) * | 1999-03-17 | 2003-09-30 | Albany Molecular Research, Inc. | 6-substituted biaryl purine derivatives as potent cyclin/CDK inhibitors and antiproliferative agents |
AU2001242629B2 (en) | 2000-03-29 | 2005-08-11 | Cyclacel Limited | 2-substituted 4-heteroaryl-pyrimidines and their use in the treatment of proliferative disorders |
GB0107901D0 (en) | 2001-03-29 | 2001-05-23 | Cyclacel Ltd | Anti-cancer compounds |
GB2378180B8 (en) * | 2001-06-27 | 2009-10-21 | Cyclacel Ltd | New purine derivatives |
US6812232B2 (en) * | 2001-09-11 | 2004-11-02 | Amr Technology, Inc. | Heterocycle substituted purine derivatives as potent antiproliferative agents |
US6667311B2 (en) * | 2001-09-11 | 2003-12-23 | Albany Molecular Research, Inc. | Nitrogen substituted biaryl purine derivatives as potent antiproliferative agents |
CA2460909A1 (en) | 2001-09-28 | 2003-04-10 | Cyclacel Limited | N-(4-(4-methylthiazol-5-yl) pyrimidin-2-yl) -n-phenylamines as antiproliferative compounds |
US6949644B2 (en) | 2001-10-12 | 2005-09-27 | Irm Llc | Methods for the synthesis of substituted purines |
EP1578722A4 (de) | 2001-10-12 | 2006-09-06 | Irm Llc | Kinaseinhibitorgerüste und verfahren zu deren herstellung |
KR20040076278A (ko) | 2002-01-10 | 2004-08-31 | 노파르티스 아게 | 라파마이신 및 그의 유도체를 포함하는, 혈관 질환의 예방및 치료를 위한 약물 전달 시스템 |
US20030229105A1 (en) * | 2002-05-21 | 2003-12-11 | Cyclacel Limited | Treatment of autoimmune disorders |
GB0219054D0 (en) * | 2002-08-15 | 2002-09-25 | Cyclacel Ltd | New purine derivatives |
GB0219052D0 (en) * | 2002-08-15 | 2002-09-25 | Cyclacel Ltd | New puring derivatives |
GB0226583D0 (en) | 2002-11-14 | 2002-12-18 | Cyclacel Ltd | Compounds |
GB0226582D0 (en) | 2002-11-14 | 2002-12-18 | Cyclacel Ltd | Anti-viral compounds |
GB0229581D0 (en) | 2002-12-19 | 2003-01-22 | Cyclacel Ltd | Use |
GB0302220D0 (en) | 2003-01-30 | 2003-03-05 | Cyclacel Ltd | Use |
GB0315966D0 (en) | 2003-07-08 | 2003-08-13 | Cyclacel Ltd | Compounds |
WO2005012298A1 (en) | 2003-07-30 | 2005-02-10 | Cyclacel Limited | Pyridinylamino-pyrimidine derivatives as protein kinase inhibitors |
CA2533474A1 (en) | 2003-07-30 | 2005-02-10 | Shudong Wang | 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors |
JP5164380B2 (ja) | 2003-10-21 | 2013-03-21 | サイクラセル リミテッド | ピリミジン−4−イル−3,4−チオン化合物及び治療におけるその使用 |
EP1740587A4 (de) * | 2004-04-02 | 2009-07-15 | Adenosine Therapeutics Llc | Selektive antagonisten von a2a-adenosinrezeptoren |
AU2005276231A1 (en) | 2004-08-27 | 2006-03-02 | Cyclacel Limited | Purine and pyrimidine CDK inhibitors and their use for the treatment of autoimmune diseases |
-
2002
- 2002-08-15 GB GBGB0219052.8A patent/GB0219052D0/en not_active Ceased
-
2003
- 2003-08-13 DE DE60304871T patent/DE60304871T2/de not_active Expired - Lifetime
- 2003-08-13 CN CNB038194295A patent/CN1312152C/zh not_active Expired - Fee Related
- 2003-08-13 AT AT03787886T patent/ATE324374T1/de active
- 2003-08-13 EP EP03787886A patent/EP1534708B1/de not_active Expired - Lifetime
- 2003-08-13 BR BR0313480-6A patent/BR0313480A/pt not_active IP Right Cessation
- 2003-08-13 CA CA2488834A patent/CA2488834C/en not_active Expired - Lifetime
- 2003-08-13 JP JP2004528662A patent/JP4787495B2/ja not_active Expired - Fee Related
- 2003-08-13 AU AU2003251063A patent/AU2003251063B2/en not_active Ceased
- 2003-08-13 NZ NZ538136A patent/NZ538136A/en not_active IP Right Cessation
- 2003-08-13 MX MXPA05001842A patent/MXPA05001842A/es active IP Right Grant
- 2003-08-13 BR BRPI0313480-6A patent/BRPI0313480B1/pt unknown
- 2003-08-13 WO PCT/GB2003/003544 patent/WO2004016613A2/en active IP Right Grant
- 2003-08-15 GB GB0319258A patent/GB2392156B/en not_active Expired - Fee Related
-
2005
- 2005-02-09 IL IL166783A patent/IL166783A/en active IP Right Grant
- 2005-09-28 US US11/238,533 patent/US7544689B2/en not_active Expired - Fee Related
-
2009
- 2009-04-30 US US12/433,388 patent/US20090270427A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60304871D1 (de) | 2006-06-01 |
WO2004016613A3 (en) | 2004-04-08 |
IL166783A0 (en) | 2006-01-15 |
NZ538136A (en) | 2007-06-29 |
IL166783A (en) | 2013-09-30 |
CA2488834C (en) | 2011-11-01 |
GB0319258D0 (en) | 2003-09-17 |
AU2003251063A1 (en) | 2004-03-03 |
BR0313480A (pt) | 2005-06-21 |
US20060183760A1 (en) | 2006-08-17 |
EP1534708B1 (de) | 2006-04-26 |
GB2392156A (en) | 2004-02-25 |
US7544689B2 (en) | 2009-06-09 |
CA2488834A1 (en) | 2004-02-26 |
EP1534708A2 (de) | 2005-06-01 |
MXPA05001842A (es) | 2005-04-19 |
GB0219052D0 (en) | 2002-09-25 |
US20090270427A1 (en) | 2009-10-29 |
CN1675213A (zh) | 2005-09-28 |
JP4787495B2 (ja) | 2011-10-05 |
JP2006509728A (ja) | 2006-03-23 |
DE60304871T2 (de) | 2006-08-31 |
CN1312152C (zh) | 2007-04-25 |
GB2392156B (en) | 2005-03-30 |
WO2004016613A2 (en) | 2004-02-26 |
BRPI0313480B1 (pt) | 2017-12-19 |
AU2003251063B2 (en) | 2009-03-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL166784A0 (en) | New purine derivatives | |
IL166783A0 (en) | New purine derivatives | |
DE602004017479D1 (de) | Als neue antiangiogene mittel geeignete thienopyridinphenylacetamide und derivate davon | |
CY1116119T1 (el) | Παραγωγα ισοξαζολο-πυριδινης | |
EA200400466A1 (ru) | Производные пиперазина с антагонистической активностью к рецептору ccr1 | |
DE602005023015D1 (de) | Indolderivate als viruzide | |
RS107504A (en) | Benzofused heteroaryl amide derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compostions including the same, and methods for their use | |
HUP0203739A2 (hu) | A hatos-gyűrűn helyettesített biciklikus imidazo-3-il-amin-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
ATE487690T1 (de) | 2-aminobicyclo 3.1.0 hexan-2,6- dicarbonsäureesterderivat | |
NO930143D0 (no) | Piperidinforbindelser, deres fremstilling og bruk | |
ATE388939T1 (de) | N-((piperazinyl)hetaryl)arylsulfonamid-derivate mit affinität zum dopamin-d3-rezeptor | |
DK0599240T3 (da) | Indol-7-carboxamidderivater som analgetika | |
ATE135206T1 (de) | Arylalkylamine und -amide mit krampflösender und nervenschützender wirkung | |
ATE378339T1 (de) | Diazaspiropiperidinderivate als inhibitoren von glycintransporter 1 und glycintransporter 2 | |
BG105126A (en) | Tetrahydronaphthyridinyl-carboxamides have anti-convulsant activity | |
ATE488516T1 (de) | 14,15-dihydro-20,21-dinoreburnamenin-14-ol- derivate und deren anwendung | |
TH63748A (th) | สารต้านฤทธิ์แบคทีเรีย ชนิด 3-อะมิโนควินาโซลิน-2,4-ไดโอน |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1534708 Country of ref document: EP |