ATE323721T1 - Cholin-bindendes protein, welches als gegen pneumokokken gerichtetes vakzin verwendet wird - Google Patents
Cholin-bindendes protein, welches als gegen pneumokokken gerichtetes vakzin verwendet wirdInfo
- Publication number
- ATE323721T1 ATE323721T1 AT97922539T AT97922539T ATE323721T1 AT E323721 T1 ATE323721 T1 AT E323721T1 AT 97922539 T AT97922539 T AT 97922539T AT 97922539 T AT97922539 T AT 97922539T AT E323721 T1 ATE323721 T1 AT E323721T1
- Authority
- AT
- Austria
- Prior art keywords
- choline binding
- bacterial
- binding protein
- binding proteins
- choline
- Prior art date
Links
- 101710164918 Choline-binding protein Proteins 0.000 title abstract 4
- 229940124733 pneumococcal vaccine Drugs 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 abstract 6
- 108091016312 choline binding proteins Proteins 0.000 abstract 6
- 241000894006 Bacteria Species 0.000 abstract 1
- 102000016359 Fibronectins Human genes 0.000 abstract 1
- 108010067306 Fibronectins Proteins 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 102000012288 Phosphopyruvate Hydratase Human genes 0.000 abstract 1
- 108010022181 Phosphopyruvate Hydratase Proteins 0.000 abstract 1
- 241000194017 Streptococcus Species 0.000 abstract 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 abstract 1
- 229960001231 choline Drugs 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1663296P | 1996-05-01 | 1996-05-01 | |
| US64225096A | 1996-05-01 | 1996-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE323721T1 true ATE323721T1 (de) | 2006-05-15 |
Family
ID=26688869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97922539T ATE323721T1 (de) | 1996-05-01 | 1997-05-01 | Cholin-bindendes protein, welches als gegen pneumokokken gerichtetes vakzin verwendet wird |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0912608B1 (2) |
| JP (1) | JP2000511411A (2) |
| AT (1) | ATE323721T1 (2) |
| AU (1) | AU732520B2 (2) |
| CA (1) | CA2253252A1 (2) |
| DE (1) | DE69735715T2 (2) |
| ES (1) | ES2262177T3 (2) |
| WO (1) | WO1997041151A2 (2) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7078042B2 (en) | 1995-09-15 | 2006-07-18 | Uab Research Foundation | Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor |
| US6245335B1 (en) | 1996-05-01 | 2001-06-12 | The Rockefeller University | Choline binding proteins for anti-pneumococcal vaccines |
| WO1998021337A2 (en) * | 1996-11-12 | 1998-05-22 | Regents Of The University Of Minnesota | C3 BINDING PROTEIN OF $i(STREPTOCOCCUS PNEUMONIAE) |
| DE19708537A1 (de) * | 1997-03-03 | 1998-09-10 | Biotechnolog Forschung Gmbh | Neues Oberflächenprotein (SpsA-Protein) von Streptococcus pneumoniae etc. |
| US6676943B1 (en) | 1997-04-24 | 2004-01-13 | Regents Of The University Of Minnesota | Human complement C3-degrading protein from Streptococcus pneumoniae |
| DE69942176D1 (de) * | 1998-04-07 | 2010-05-06 | Medimmune Llc | Choline-bindende proteine derivate aus pneumokoken als impfstoff |
| US6858706B2 (en) | 1998-04-07 | 2005-02-22 | St. Jude Children's Research Hospital | Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof |
| TR200003498T2 (tr) * | 1998-04-07 | 2001-10-22 | St. Jude Children's Research Hospital | Amino asit sekansından oluşan bir polipetit, bunun aşıları ve kullanımları |
| AU2004200125B2 (en) * | 1998-04-07 | 2006-07-27 | Med Immune, Inc. | Derivatives of Pneumococcal Choline Binding Proteins for Vaccines |
| US20010016200A1 (en) | 1998-04-23 | 2001-08-23 | Briles David E. | Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor |
| WO2000029434A2 (en) * | 1998-11-19 | 2000-05-25 | St. Jude Children's Research Hospital | PNEUMOCOCCAL CHOLINE BINDING PROTEINS, CbpG AND CbpD, DIAGNOSTIC AND THERAPEUTIC USES THEREOF |
| US6495139B2 (en) | 1998-11-19 | 2002-12-17 | St. Jude Children's Research Hospital | Identification and characterization of novel pneumococcal choline binding protein, CBPG, and diagnostic and therapeutic uses thereof |
| ES2322306T3 (es) | 1998-12-21 | 2009-06-18 | Medimmune, Inc. | Proteinas de streptpcpccus pneumoniae y fragmentos inmunogenicos para vacunas. |
| ES2275499T3 (es) | 1999-03-19 | 2007-06-16 | Glaxosmithkline Biologicals S.A. | Vacuna contra streptococcus pneumoniae. |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| EP1524991A1 (en) | 2002-08-02 | 2005-04-27 | GlaxoSmithKline Biologicals S.A. | Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria |
| EP2395073B1 (en) | 2002-11-01 | 2017-09-06 | GlaxoSmithKline Biologicals S.A. | Drying process |
| DE602004028262D1 (de) | 2003-10-02 | 2010-09-02 | Glaxosmithkline Biolog Sa | B. pertussis antigene und ihre verwendung bei der vakzinierung |
| GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| PL1973564T3 (pl) | 2005-12-22 | 2017-04-28 | Glaxosmithkline Biologicals S.A. | Szczepionki zawierające koniugaty polisacharydu otoczkowego streptococcus pneumoniae |
| AU2007206114B2 (en) | 2006-01-17 | 2013-01-24 | Arne Forsgren | A novel surface exposed Haemophilus influenzae protein (protein E; pE) |
| SI2167121T1 (sl) | 2007-06-26 | 2015-12-31 | Glaxosmithkline Biologicals S.A. | Cepivo, ki obsega kapsularne polisaharidne konjugate Streptococcusa pneumoniae |
| SI2271360T1 (sl) | 2008-04-16 | 2015-12-31 | Glaxosmithkline Biologicals S.A. | Cepivo |
| JP5197846B2 (ja) * | 2009-04-30 | 2013-05-15 | 紀陽 田仲 | 腎疾患重篤度を判定する方法又は装置若しくはその作動方法 |
| GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2544714A1 (en) | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Vaccine composition |
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| WO2012156391A1 (en) | 2011-05-17 | 2012-11-22 | Glaxosmithkline Biologicals S.A. | Vaccine against streptococcus pneumoniae |
| WO2014186796A1 (en) | 2013-05-17 | 2014-11-20 | The Board Of Regents Of The University Of Texas System | Immunization to protect against adverse cardiac events relating to pneumococcal infection |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| GB201711635D0 (en) | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| EP4061924A1 (en) * | 2019-11-18 | 2022-09-28 | Vaxcyte, Inc. | Animal product-free culture of streptococcus bacteria |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4400293A (en) * | 1992-05-29 | 1993-12-30 | Janet Yother | Methods for obtaining and purifying cell-free pneumococcal surface proteins from (s. pneumoniae) and use thereof |
| CA2116261A1 (en) * | 1993-04-20 | 1994-10-21 | David E. Briles | Epitopic regions of pneumococcal surface protein a |
| CZ394297A3 (cs) * | 1995-06-07 | 1998-04-15 | Biochem Vaccines Inc. | Streptokokové proteiny teplotního šoku ze skupiny HSP70 |
-
1997
- 1997-05-01 DE DE69735715T patent/DE69735715T2/de not_active Expired - Lifetime
- 1997-05-01 ES ES97922539T patent/ES2262177T3/es not_active Expired - Lifetime
- 1997-05-01 CA CA002253252A patent/CA2253252A1/en not_active Abandoned
- 1997-05-01 AU AU28182/97A patent/AU732520B2/en not_active Ceased
- 1997-05-01 JP JP09539170A patent/JP2000511411A/ja active Pending
- 1997-05-01 EP EP97922539A patent/EP0912608B1/en not_active Expired - Lifetime
- 1997-05-01 WO PCT/US1997/007198 patent/WO1997041151A2/en not_active Ceased
- 1997-05-01 AT AT97922539T patent/ATE323721T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2818297A (en) | 1997-11-19 |
| JP2000511411A (ja) | 2000-09-05 |
| ES2262177T3 (es) | 2006-11-16 |
| DE69735715T2 (de) | 2007-03-29 |
| AU732520B2 (en) | 2001-04-26 |
| DE69735715D1 (de) | 2006-05-24 |
| CA2253252A1 (en) | 1997-11-06 |
| EP0912608B1 (en) | 2006-04-19 |
| WO1997041151A2 (en) | 1997-11-06 |
| EP0912608A2 (en) | 1999-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |