ATE319741T1 - Gereinigte thrombopoietin und verfahren zur herstellung davon - Google Patents
Gereinigte thrombopoietin und verfahren zur herstellung davonInfo
- Publication number
- ATE319741T1 ATE319741T1 AT95943915T AT95943915T ATE319741T1 AT E319741 T1 ATE319741 T1 AT E319741T1 AT 95943915 T AT95943915 T AT 95943915T AT 95943915 T AT95943915 T AT 95943915T AT E319741 T1 ATE319741 T1 AT E319741T1
- Authority
- AT
- Austria
- Prior art keywords
- thrombopoietin
- proteins
- eluted
- producing
- purified
- Prior art date
Links
- 102000036693 Thrombopoietin Human genes 0.000 title abstract 4
- 108010041111 Thrombopoietin Proteins 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000005571 anion exchange chromatography Methods 0.000 abstract 1
- 108020001756 ligand binding domains Proteins 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36685994A | 1994-12-30 | 1994-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE319741T1 true ATE319741T1 (de) | 2006-03-15 |
Family
ID=23444867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95943915T ATE319741T1 (de) | 1994-12-30 | 1995-12-20 | Gereinigte thrombopoietin und verfahren zur herstellung davon |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5986049A (de) |
| EP (1) | EP0804480B1 (de) |
| JP (1) | JPH10511681A (de) |
| CN (1) | CN1171791A (de) |
| AT (1) | ATE319741T1 (de) |
| AU (1) | AU4526096A (de) |
| CA (1) | CA2207577A1 (de) |
| DE (1) | DE69534853D1 (de) |
| MX (1) | MX9703959A (de) |
| NZ (1) | NZ300500A (de) |
| WO (1) | WO1996020955A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR19990081421A (ko) * | 1998-04-29 | 1999-11-15 | 성재갑 | 동물세포를 이용한 인간 혈소판 생성 촉진인자(tpo)의 제조방법 |
| US8236048B2 (en) | 2000-05-12 | 2012-08-07 | Cordis Corporation | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| AU2001294869B2 (en) | 2000-09-29 | 2006-06-15 | Cardinal Health 529, Llc | Coated medical devices |
| US20040028661A1 (en) * | 2002-08-07 | 2004-02-12 | Bartelmez Stephen H. | Expansion of cells using thrombopoietin and anti-transforming growth factor-beta |
| KR100473703B1 (ko) * | 2002-08-23 | 2005-03-10 | 한미약품 주식회사 | 형질전환 동물의 젖으로부터 재조합 펩타이드 또는단백질의 정제 방법 |
| CN100432102C (zh) * | 2004-09-30 | 2008-11-12 | 百瑞全球有限公司 | 血小板增进蛋白及其应用 |
| CN105168250B (zh) | 2004-10-25 | 2019-02-05 | 塞勒兰特治疗公司 | 增殖骨髓细胞群体的方法及其应用 |
| US7879318B2 (en) * | 2006-01-23 | 2011-02-01 | Mcw Research Foundation, Inc. | Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand |
| CN102033010B (zh) * | 2010-11-26 | 2013-02-20 | 四川农业大学 | 一种垂直板电泳中凝胶点样顺序及凝胶顺序的双重标示方法 |
| CN105541994B (zh) * | 2015-12-01 | 2019-12-06 | 沈阳三生制药有限责任公司 | 一种血小板生成素或其变体或衍生物的纯化方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2084074A1 (en) * | 1990-05-31 | 1991-12-01 | Keita Matsunaga | Megakaryocyte colony stimulating factor and production thereof |
| GB2285446B (en) * | 1994-01-03 | 1999-07-28 | Genentech Inc | Thrombopoietin |
| US5541085A (en) * | 1994-02-14 | 1996-07-30 | Zymogenetics, Inc. | Method for preparing orphan receptor ligands |
| WO1995021919A2 (en) * | 1994-02-14 | 1995-08-17 | Kirin Brewery Company, Limited | Protein having tpo activity |
| SK166695A3 (en) * | 1994-03-31 | 1997-02-05 | Amgen Inc | Mgdf polypeptide for stimulating growth and megakaryocyte differentiation |
-
1995
- 1995-06-01 US US08/457,254 patent/US5986049A/en not_active Expired - Fee Related
- 1995-12-20 DE DE69534853T patent/DE69534853D1/de not_active Expired - Lifetime
- 1995-12-20 CN CN95197200A patent/CN1171791A/zh active Pending
- 1995-12-20 MX MX9703959A patent/MX9703959A/es not_active IP Right Cessation
- 1995-12-20 EP EP95943915A patent/EP0804480B1/de not_active Expired - Lifetime
- 1995-12-20 AT AT95943915T patent/ATE319741T1/de not_active IP Right Cessation
- 1995-12-20 NZ NZ300500A patent/NZ300500A/en unknown
- 1995-12-20 CA CA002207577A patent/CA2207577A1/en not_active Abandoned
- 1995-12-20 AU AU45260/96A patent/AU4526096A/en not_active Abandoned
- 1995-12-20 WO PCT/US1995/016626 patent/WO1996020955A1/en active IP Right Grant
- 1995-12-20 JP JP8521067A patent/JPH10511681A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69534853D1 (de) | 2006-05-04 |
| WO1996020955A1 (en) | 1996-07-11 |
| CA2207577A1 (en) | 1996-07-11 |
| US5986049A (en) | 1999-11-16 |
| EP0804480B1 (de) | 2006-03-08 |
| JPH10511681A (ja) | 1998-11-10 |
| AU4526096A (en) | 1996-07-24 |
| EP0804480A1 (de) | 1997-11-05 |
| CN1171791A (zh) | 1998-01-28 |
| MX9703959A (es) | 1998-01-31 |
| NZ300500A (en) | 1999-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |