ATE123068T1 - Verfahren zur herstellung eines proteins durch hefe mit hilfe eines induzierbaren systems, vektoren und entsprechende transformierte stämme. - Google Patents

Verfahren zur herstellung eines proteins durch hefe mit hilfe eines induzierbaren systems, vektoren und entsprechende transformierte stämme.

Info

Publication number
ATE123068T1
ATE123068T1 AT89401871T AT89401871T ATE123068T1 AT E123068 T1 ATE123068 T1 AT E123068T1 AT 89401871 T AT89401871 T AT 89401871T AT 89401871 T AT89401871 T AT 89401871T AT E123068 T1 ATE123068 T1 AT E123068T1
Authority
AT
Austria
Prior art keywords
yeast
ligand
protein
receptor
cells
Prior art date
Application number
AT89401871T
Other languages
English (en)
Inventor
Pierre Henry Chambon
Daniel Metzger
John White
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE123068T1 publication Critical patent/ATE123068T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Instructional Devices (AREA)
  • Prostheses (AREA)
AT89401871T 1988-07-01 1989-06-29 Verfahren zur herstellung eines proteins durch hefe mit hilfe eines induzierbaren systems, vektoren und entsprechende transformierte stämme. ATE123068T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8808978A FR2634495B1 (fr) 1988-07-01 1988-07-01 Procede de preparation d'une proteine par des levures utilisant un systeme inductible, vecteurs et souches transformees correspondantes

Publications (1)

Publication Number Publication Date
ATE123068T1 true ATE123068T1 (de) 1995-06-15

Family

ID=9368010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89401871T ATE123068T1 (de) 1988-07-01 1989-06-29 Verfahren zur herstellung eines proteins durch hefe mit hilfe eines induzierbaren systems, vektoren und entsprechende transformierte stämme.

Country Status (10)

Country Link
US (2) US6444438B1 (de)
EP (1) EP0349435B1 (de)
JP (1) JP2973430B2 (de)
AT (1) ATE123068T1 (de)
CA (1) CA1341192C (de)
DE (1) DE68922790T2 (de)
DK (1) DK176000B1 (de)
ES (1) ES2075068T3 (de)
FR (1) FR2634495B1 (de)
GR (1) GR3016996T3 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645174B1 (fr) * 1989-03-31 1994-01-07 Transgene Sa Souches de levure ameliorees pour la production de proteines heterologues matures en particulier d'hirudine et procede de preparation d'hirudine correspondant
US5879926A (en) * 1989-03-31 1999-03-09 Transgene S.A. Yeast strains for the production of mature heterologous proteins, especially hirudin
FR2645175B1 (fr) * 1989-03-31 1994-02-18 Transgene Sa Souche de saccharomyces cerevisiaeproductrice d'une proteine heterologue et procede de preparation de ladite proteine heterologue par fermentation de ladite souche
FR2649994A1 (fr) * 1989-06-30 1991-01-25 Aderegem Procede d'obtention d'un recepteur humain natif sauvage des oestrogenes et ses applications
EP0441483A3 (en) * 1990-01-16 1992-11-19 Baylor College Of Medicine Expression vectors that produce steroid receptors, steroid receptor chimera, screening assays for steroid receptors and clinical assays using synthesized receptors and receptor vectors
US5733732A (en) * 1996-01-03 1998-03-31 University Of Iowa Research Foundation Methods for detecting primary adhalinopathy
AU782142B2 (en) * 1999-12-07 2005-07-07 Sumitomo Chemical Company, Limited Mutant ERalpha and test systems for transactivation
US6737262B1 (en) * 2000-07-11 2004-05-18 Robert I. Bolla Animal feed containing polypeptides
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
WO2004058947A2 (en) * 2002-12-23 2004-07-15 Glycofi, Inc. Steroid receptor modulation of gene expression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8620926D0 (en) * 1986-08-29 1986-10-08 Delta Biotechnology Ltd Yeast promoter
US5071773A (en) * 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
MY103358A (en) * 1987-04-15 1993-06-30 Novartis Ag Process for the production of protiens.

Also Published As

Publication number Publication date
DE68922790D1 (de) 1995-06-29
DE68922790T2 (de) 1995-11-30
US5817503A (en) 1998-10-06
US6444438B1 (en) 2002-09-03
CA1341192C (fr) 2001-02-27
DK176000B1 (da) 2005-11-14
JP2973430B2 (ja) 1999-11-08
ES2075068T3 (es) 1995-10-01
EP0349435A1 (de) 1990-01-03
FR2634495A1 (fr) 1990-01-26
DK326289D0 (da) 1989-06-30
DK326289A (da) 1990-01-02
GR3016996T3 (en) 1995-11-30
FR2634495B1 (fr) 1990-10-26
EP0349435B1 (de) 1995-05-24
JPH02242693A (ja) 1990-09-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time