ATE319687T1 - Verfahren zur herstellung von substituierten pyridinen - Google Patents

Verfahren zur herstellung von substituierten pyridinen

Info

Publication number
ATE319687T1
ATE319687T1 AT97945047T AT97945047T ATE319687T1 AT E319687 T1 ATE319687 T1 AT E319687T1 AT 97945047 T AT97945047 T AT 97945047T AT 97945047 T AT97945047 T AT 97945047T AT E319687 T1 ATE319687 T1 AT E319687T1
Authority
AT
Austria
Prior art keywords
substituted pyridines
producing substituted
producing
pyridines
substituted
Prior art date
Application number
AT97945047T
Other languages
German (de)
English (en)
Inventor
Keith Michael Devries
Robert Lee Dow
Stephen Wayne Wright
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE319687T1 publication Critical patent/ATE319687T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97945047T 1996-11-14 1997-11-03 Verfahren zur herstellung von substituierten pyridinen ATE319687T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3088096P 1996-11-14 1996-11-14

Publications (1)

Publication Number Publication Date
ATE319687T1 true ATE319687T1 (de) 2006-03-15

Family

ID=21856496

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97945047T ATE319687T1 (de) 1996-11-14 1997-11-03 Verfahren zur herstellung von substituierten pyridinen

Country Status (32)

Country Link
US (1) US6291489B1 (US06291489-20010918-C00045.png)
EP (1) EP0938476B1 (US06291489-20010918-C00045.png)
JP (1) JP3510635B2 (US06291489-20010918-C00045.png)
KR (1) KR20000053314A (US06291489-20010918-C00045.png)
CN (1) CN1237160A (US06291489-20010918-C00045.png)
AP (1) AP805A (US06291489-20010918-C00045.png)
AR (1) AR010584A1 (US06291489-20010918-C00045.png)
AT (1) ATE319687T1 (US06291489-20010918-C00045.png)
AU (1) AU4634697A (US06291489-20010918-C00045.png)
BG (1) BG103393A (US06291489-20010918-C00045.png)
BR (1) BR9712951A (US06291489-20010918-C00045.png)
CA (1) CA2270386C (US06291489-20010918-C00045.png)
CO (1) CO4930261A1 (US06291489-20010918-C00045.png)
DE (1) DE69735433D1 (US06291489-20010918-C00045.png)
EA (1) EA199900375A1 (US06291489-20010918-C00045.png)
GT (1) GT199700118A (US06291489-20010918-C00045.png)
HR (1) HRP970612A2 (US06291489-20010918-C00045.png)
ID (1) ID18898A (US06291489-20010918-C00045.png)
IL (1) IL129688A0 (US06291489-20010918-C00045.png)
IS (1) IS5029A (US06291489-20010918-C00045.png)
MA (1) MA24401A1 (US06291489-20010918-C00045.png)
MY (1) MY132507A (US06291489-20010918-C00045.png)
NO (1) NO992296L (US06291489-20010918-C00045.png)
OA (1) OA11044A (US06291489-20010918-C00045.png)
PA (1) PA8441401A1 (US06291489-20010918-C00045.png)
PE (1) PE10299A1 (US06291489-20010918-C00045.png)
TN (1) TNSN97172A1 (US06291489-20010918-C00045.png)
TR (1) TR199901063T2 (US06291489-20010918-C00045.png)
UY (1) UY24774A1 (US06291489-20010918-C00045.png)
WO (1) WO1998021184A1 (US06291489-20010918-C00045.png)
YU (1) YU22099A (US06291489-20010918-C00045.png)
ZA (1) ZA9710186B (US06291489-20010918-C00045.png)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511460A (ja) * 1998-04-08 2002-04-16 ノバルティス アクチエンゲゼルシャフト 新規除草剤
US6090942A (en) * 1998-10-15 2000-07-18 Pfizer Inc. Process and intermediates for a β3 -adrenergic receptor agonist
US6515134B1 (en) * 1999-02-16 2003-02-04 Kaneka Corporation Substituted acetylpridine derivatives and process for the preparation of intermediates for optically active beta-3 agonist by the use of the same
US6455734B1 (en) 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
ATE280167T1 (de) * 1999-07-23 2004-11-15 Pfizer Prod Inc Zwischenprodukte und ein verfahren zur herstellung von beta3-adrenergischer rezeptor- agoniste
JPWO2003033468A1 (ja) * 2001-10-17 2005-02-03 株式会社カネカ (S)−α−ハロメチルピリジンメタノール誘導体の製造方法
AU2003248352A1 (en) 2002-02-27 2003-09-09 Pfizer Products Inc. PROCESSES AND INTERMEDIATES USEFUL IN PREPARING Beta3-ADRENERGIC RECEPTOR AGONISTS
AU2003209527A1 (en) * 2002-02-27 2003-09-09 Pfizer Products Inc. Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol
US6864268B2 (en) 2002-02-27 2005-03-08 Pfizer Inc. β3 adrenergic receptor agonists
EP1424079A1 (en) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine
KR100751163B1 (ko) 2003-05-09 2007-08-22 에프. 호프만-라 로슈 아게 알파-1 아드레날린 작용물질로서의 메틸 인돌 및 메틸피롤로피리딘
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
JP5791500B2 (ja) 2008-05-23 2015-10-07 パンミラ ファーマシューティカルズ,エルエルシー. 5−リポキシゲナーゼ活性化タンパク質阻害剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358455A (en) 1980-12-23 1982-11-09 Merck & Co., Inc. Aralkylamindethanol heterocyclic compounds
US5019578A (en) 1987-11-27 1991-05-28 Merck & Co., Inc. β-adrenergic agonists
NZ265692A (en) 1993-06-14 1997-02-24 Pfizer Indole- and benzofuran- containing hydroxyamines and analogs; pharmaceutical compositions
IL113410A (en) 1994-04-26 1999-11-30 Merck & Co Inc Substituted sulfonamides having an asymmetric center and pharmaceutical compositions containing them
JPH11504648A (ja) 1995-05-10 1999-04-27 ファイザー・インコーポレーテッド β−アドレナリン作動性アゴニスト
EP0824519A1 (en) 1995-05-10 1998-02-25 Pfizer Inc. Beta-adrenergic agonists

Also Published As

Publication number Publication date
UY24774A1 (es) 1998-05-05
MY132507A (en) 2007-10-31
ID18898A (id) 1998-05-20
JP2000504347A (ja) 2000-04-11
ZA9710186B (en) 1999-05-12
DE69735433D1 (de) 2006-05-04
AR010584A1 (es) 2000-06-28
IL129688A0 (en) 2000-02-29
MA24401A1 (fr) 1998-07-01
PE10299A1 (es) 1999-02-10
WO1998021184A1 (en) 1998-05-22
AU4634697A (en) 1998-06-03
KR20000053314A (ko) 2000-08-25
OA11044A (en) 2002-02-20
TNSN97172A1 (fr) 2005-03-15
AP805A (en) 2000-01-28
NO992296D0 (no) 1999-05-12
TR199901063T2 (xx) 1999-08-23
IS5029A (is) 1999-04-16
CA2270386A1 (en) 1998-05-22
NO992296L (no) 1999-05-12
PA8441401A1 (es) 2000-05-24
CO4930261A1 (es) 2000-06-27
EP0938476B1 (en) 2006-03-08
YU22099A (sh) 2001-09-28
HRP970612A2 (en) 1998-08-31
BG103393A (en) 2000-07-31
EP0938476A1 (en) 1999-09-01
CA2270386C (en) 2004-08-03
AP9701147A0 (en) 1998-01-31
BR9712951A (pt) 1999-12-07
CN1237160A (zh) 1999-12-01
US6291489B1 (en) 2001-09-18
EA199900375A1 (ru) 1999-12-29
JP3510635B2 (ja) 2004-03-29
GT199700118A (es) 1999-05-05

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties