ATE318800T1 - Indolderivate als mcp-1 rezeptor antagonisten - Google Patents

Indolderivate als mcp-1 rezeptor antagonisten

Info

Publication number
ATE318800T1
ATE318800T1 AT01900197T AT01900197T ATE318800T1 AT E318800 T1 ATE318800 T1 AT E318800T1 AT 01900197 T AT01900197 T AT 01900197T AT 01900197 T AT01900197 T AT 01900197T AT E318800 T1 ATE318800 T1 AT E318800T1
Authority
AT
Austria
Prior art keywords
sup
halo
hydrogen
methoxy
lower alkyl
Prior art date
Application number
AT01900197T
Other languages
English (en)
Inventor
Alan Wellington Faull
Jason Grant Kettle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of ATE318800T1 publication Critical patent/ATE318800T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01900197T 2000-01-13 2001-01-09 Indolderivate als mcp-1 rezeptor antagonisten ATE318800T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0000625.4A GB0000625D0 (en) 2000-01-13 2000-01-13 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE318800T1 true ATE318800T1 (de) 2006-03-15

Family

ID=9883550

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01900197T ATE318800T1 (de) 2000-01-13 2001-01-09 Indolderivate als mcp-1 rezeptor antagonisten

Country Status (17)

Country Link
US (1) US6984657B1 (de)
EP (1) EP1268423B1 (de)
JP (1) JP2003519684A (de)
KR (1) KR20020064374A (de)
CN (1) CN1395564A (de)
AT (1) ATE318800T1 (de)
AU (1) AU779502B2 (de)
BR (1) BR0107405A (de)
CA (1) CA2393597A1 (de)
DE (1) DE60117517T2 (de)
GB (1) GB0000625D0 (de)
IL (1) IL150276A0 (de)
MX (1) MXPA02006612A (de)
NO (1) NO20023381L (de)
NZ (1) NZ519311A (de)
WO (1) WO2001051467A1 (de)
ZA (1) ZA200204351B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9716657D0 (en) 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
DE10022925A1 (de) * 2000-05-11 2001-11-15 Basf Ag Substituierte Indole als PARP-Inhibitoren
US20080076120A1 (en) * 2006-09-14 2008-03-27 Millennium Pharmaceuticals, Inc. Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders
WO2017163263A1 (en) 2016-03-22 2017-09-28 Council Of Scientific & Industrial Research Indole derivatives, preparation and use thereof

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GB9716657D0 (en) * 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
EP1042287B1 (de) 1997-12-24 2005-04-20 Aventis Pharma Deutschland GmbH Indolderivate als faktor xa inhibitoren
GB9902461D0 (en) * 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
KR20020064374A (ko) 2002-08-07
GB0000625D0 (en) 2000-03-01
CN1395564A (zh) 2003-02-05
BR0107405A (pt) 2002-10-08
IL150276A0 (en) 2002-12-01
MXPA02006612A (es) 2002-09-30
CA2393597A1 (en) 2001-07-19
EP1268423A1 (de) 2003-01-02
ZA200204351B (en) 2003-09-01
NO20023381L (no) 2002-09-09
DE60117517D1 (de) 2006-04-27
AU779502B2 (en) 2005-01-27
US6984657B1 (en) 2006-01-10
JP2003519684A (ja) 2003-06-24
WO2001051467A1 (en) 2001-07-19
EP1268423B1 (de) 2006-03-01
AU2387401A (en) 2001-07-24
NZ519311A (en) 2004-05-28
DE60117517T2 (de) 2006-09-21
NO20023381D0 (no) 2002-07-12

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties