ATE315556T1 - Verfahren zur herstellung eines thiazol-ppar- liganden sowie dessen polymorphe - Google Patents
Verfahren zur herstellung eines thiazol-ppar- liganden sowie dessen polymorpheInfo
- Publication number
- ATE315556T1 ATE315556T1 AT02747330T AT02747330T ATE315556T1 AT E315556 T1 ATE315556 T1 AT E315556T1 AT 02747330 T AT02747330 T AT 02747330T AT 02747330 T AT02747330 T AT 02747330T AT E315556 T1 ATE315556 T1 AT E315556T1
- Authority
- AT
- Austria
- Prior art keywords
- polymorphs
- thiazole
- producing
- ppar ligand
- compound
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 abstract 1
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113232.3A GB0113232D0 (en) | 2001-05-31 | 2001-05-31 | Chemical process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE315556T1 true ATE315556T1 (de) | 2006-02-15 |
Family
ID=9915637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02747330T ATE315556T1 (de) | 2001-05-31 | 2002-05-29 | Verfahren zur herstellung eines thiazol-ppar- liganden sowie dessen polymorphe |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7244849B2 (enExample) |
| EP (1) | EP1395572B1 (enExample) |
| JP (1) | JP2004532265A (enExample) |
| KR (1) | KR20040007631A (enExample) |
| CN (1) | CN1551871A (enExample) |
| AT (1) | ATE315556T1 (enExample) |
| AU (1) | AU2002317764B2 (enExample) |
| BR (1) | BR0209892A (enExample) |
| CA (1) | CA2448101A1 (enExample) |
| CO (1) | CO5540298A2 (enExample) |
| CZ (1) | CZ20033256A3 (enExample) |
| DE (1) | DE60208682T2 (enExample) |
| ES (1) | ES2256493T3 (enExample) |
| GB (1) | GB0113232D0 (enExample) |
| HU (1) | HUP0400117A3 (enExample) |
| IL (1) | IL158641A0 (enExample) |
| MX (1) | MXPA03010943A (enExample) |
| NO (1) | NO20035313L (enExample) |
| NZ (1) | NZ529486A (enExample) |
| PL (1) | PL367114A1 (enExample) |
| WO (1) | WO2002096893A1 (enExample) |
| ZA (1) | ZA200308570B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105551B2 (en) * | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
| BR0311834A (pt) | 2002-06-19 | 2005-04-12 | Lilly Co Eli | Composto, composição farmacêutica, métodos para mudular um receptor ativado por proliferador de peroxisoma, para tratar e prevenir diabetes mellitus em um mamìfero e para tratar sìndrome x em um mamìfero, e, uso de um composto ou seu sal farmaceuticamente aceitável |
| TW200400816A (en) | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
| US7553867B2 (en) | 2002-09-06 | 2009-06-30 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| EP1680131A4 (en) | 2003-08-01 | 2009-05-27 | Janssen Pharmaceutica Nv | SUBSTITUTED INDOLE-O-GLUCOSIDES |
| EP1734930A2 (en) * | 2004-04-09 | 2006-12-27 | Smithkline Beecham Corporation | Low dose pharmaceutical products |
| JP2009523132A (ja) * | 2006-01-10 | 2009-06-18 | スミスクライン ビーチャム コーポレーション | ｛２−メチル−４−［４−メチル−２−（４−トリフルオロメチルフェニル）チアゾール−５−イルメチルチオ］フェノキシ｝−酢酸の多形体形態 |
| WO2012168948A2 (en) * | 2011-06-06 | 2012-12-13 | Hetero Research Foundation | Process for febuxostat |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100620337B1 (ko) * | 1998-03-10 | 2006-09-13 | 오노 야꾸힝 고교 가부시키가이샤 | 카르복실산 유도체와 그 유도체를 유효 성분으로서함유하는 약제 |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| AU2002233271A1 (en) * | 2000-12-20 | 2002-07-01 | Glaxo Group Limited | Substitued oxazoles and thiazoles as hppar alpha agonists |
| GB0111523D0 (en) * | 2001-05-11 | 2001-07-04 | Glaxo Group Ltd | Chemical compounds |
| GB0113233D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
-
2001
- 2001-05-31 GB GBGB0113232.3A patent/GB0113232D0/en not_active Ceased
-
2002
- 2002-05-29 AU AU2002317764A patent/AU2002317764B2/en not_active Ceased
- 2002-05-29 ES ES02747330T patent/ES2256493T3/es not_active Expired - Lifetime
- 2002-05-29 US US10/478,260 patent/US7244849B2/en not_active Expired - Fee Related
- 2002-05-29 CZ CZ20033256A patent/CZ20033256A3/cs unknown
- 2002-05-29 KR KR10-2003-7015677A patent/KR20040007631A/ko not_active Ceased
- 2002-05-29 BR BR0209892-0A patent/BR0209892A/pt not_active IP Right Cessation
- 2002-05-29 HU HU0400117A patent/HUP0400117A3/hu unknown
- 2002-05-29 CA CA002448101A patent/CA2448101A1/en not_active Abandoned
- 2002-05-29 AT AT02747330T patent/ATE315556T1/de not_active IP Right Cessation
- 2002-05-29 PL PL02367114A patent/PL367114A1/xx not_active Application Discontinuation
- 2002-05-29 IL IL15864102A patent/IL158641A0/xx unknown
- 2002-05-29 JP JP2003500072A patent/JP2004532265A/ja active Pending
- 2002-05-29 DE DE60208682T patent/DE60208682T2/de not_active Expired - Fee Related
- 2002-05-29 MX MXPA03010943A patent/MXPA03010943A/es unknown
- 2002-05-29 NZ NZ529486A patent/NZ529486A/en unknown
- 2002-05-29 WO PCT/EP2002/005884 patent/WO2002096893A1/en not_active Ceased
- 2002-05-29 EP EP02747330A patent/EP1395572B1/en not_active Expired - Lifetime
- 2002-05-29 CN CNA02810885XA patent/CN1551871A/zh active Pending
-
2003
- 2003-11-03 ZA ZA200308570A patent/ZA200308570B/en unknown
- 2003-11-26 CO CO03104438A patent/CO5540298A2/es not_active Application Discontinuation
- 2003-11-28 NO NO20035313A patent/NO20035313L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20040007631A (ko) | 2004-01-24 |
| NO20035313D0 (no) | 2003-11-28 |
| CO5540298A2 (es) | 2005-07-29 |
| BR0209892A (pt) | 2004-06-08 |
| CA2448101A1 (en) | 2002-12-05 |
| HUP0400117A3 (en) | 2005-09-28 |
| US7244849B2 (en) | 2007-07-17 |
| CZ20033256A3 (en) | 2004-04-14 |
| EP1395572B1 (en) | 2006-01-11 |
| DE60208682T2 (de) | 2006-08-24 |
| US20040242657A1 (en) | 2004-12-02 |
| ES2256493T3 (es) | 2006-07-16 |
| AU2002317764B2 (en) | 2005-01-06 |
| JP2004532265A (ja) | 2004-10-21 |
| WO2002096893A1 (en) | 2002-12-05 |
| HUP0400117A2 (hu) | 2005-03-29 |
| PL367114A1 (en) | 2005-02-21 |
| MXPA03010943A (es) | 2004-02-27 |
| NO20035313L (no) | 2003-12-09 |
| CN1551871A (zh) | 2004-12-01 |
| EP1395572A1 (en) | 2004-03-10 |
| GB0113232D0 (en) | 2001-07-25 |
| DE60208682D1 (de) | 2006-04-06 |
| ZA200308570B (en) | 2005-02-03 |
| NZ529486A (en) | 2005-12-23 |
| IL158641A0 (en) | 2004-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004005323D1 (de) | Azidfreies verfahren zur herstellung von 1,2-diaminoverbindungen | |
| CY1110631T1 (el) | Διαλυτοποιημενα δηλητηρια τοποϊσομερασης | |
| ATE419239T1 (de) | Verfahren zur herstellung von 4-phenoxy chinolin derivaten | |
| ATE425136T1 (de) | Verfahren zur herstellung substituierter 3-aryl- butyl-aminverbindungen | |
| JO2413B1 (en) | Benzoxazine derivatives and their use | |
| ATE246180T1 (de) | Benzofuranon-derivate und verfahren zu ihrer herstellung | |
| ATE315556T1 (de) | Verfahren zur herstellung eines thiazol-ppar- liganden sowie dessen polymorphe | |
| MY138466A (en) | Aminoalkoxyndoles as 5-ht6-receptor ligands for the treatment of cns-disorders | |
| ATE407127T1 (de) | Verfahren zur herstellung von beraprost und dessen salzen | |
| ATE241589T1 (de) | Verfahren zur herstellung des neuraminidase- inhibitoren ro-64-0796 | |
| BR0209901A (pt) | Processos para a sìntese de derivados de 2,3-dihidro-1,4-dioxino-[2,3-f] quinolina | |
| DE60231426D1 (de) | Solubilisierte topoisomerase-gift-mittel | |
| ATE275149T1 (de) | Verfahren zur herstellung von taxanderivaten | |
| ATE339202T1 (de) | Verwendung von alpha-halogenacryloyl-distamycin derivaten zur herstellung eines medikaments zur behandlung von krebs | |
| ATE277887T1 (de) | Verfahren zur herstellung von 1,4-bis((2- (dimethylamino)ethyl amino)-5,8- dihydroxyanthracene-9,10-dion | |
| DE60224884D1 (de) | Verfahren zur herstellung von 3, 3', 6, 6'-tetraalkylen-2, 2'-biphenolen und 3, 3', 6, 6'-tetraalkylen-5, 5'-dihalo-2, 2' biphenolen | |
| ATE496038T1 (de) | Verfahren zur herstellung von quetiapin | |
| SG149005A1 (en) | Process for the preparation of thiazolopyrimidines | |
| DE60234279D1 (de) | Verfahren zur herstellung eines immunosuppresivums | |
| ATE280769T1 (de) | Verfahren zur herstellung von vitronectin- rezeptorantagonisten | |
| WO2007014839A3 (en) | Cathepsin k inhibitors | |
| DE60107292D1 (de) | Verfahren zur herstellung von (+)-trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidin | |
| DE69414586D1 (de) | Verfahren zur herstellung von indolizinderivaten | |
| ATE330612T1 (de) | Verfahren zur herstellung von benazeprilhydrochloride | |
| ATE297478T1 (de) | Verfahren zur herstellung von orthocarbonsäuretrialkylestern |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |