ATE311206T1 - Substituierte porphyrine - Google Patents

Substituierte porphyrine

Info

Publication number
ATE311206T1
ATE311206T1 AT99919995T AT99919995T ATE311206T1 AT E311206 T1 ATE311206 T1 AT E311206T1 AT 99919995 T AT99919995 T AT 99919995T AT 99919995 T AT99919995 T AT 99919995T AT E311206 T1 ATE311206 T1 AT E311206T1
Authority
AT
Austria
Prior art keywords
substituted porphyrins
oxidants
compounds
relates
processes
Prior art date
Application number
AT99919995T
Other languages
German (de)
English (en)
Inventor
James D Crapo
Brian Day
Polivina Jolicia F Gauuan
Anthony D Pechulis Jr
Michael P Trova
Original Assignee
Univ Duke
Aeolus Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke, Aeolus Sciences Inc filed Critical Univ Duke
Application granted granted Critical
Publication of ATE311206T1 publication Critical patent/ATE311206T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT99919995T 1998-04-24 1999-04-23 Substituierte porphyrine ATE311206T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8288198P 1998-04-24 1998-04-24
PCT/US1999/008905 WO1999055388A1 (en) 1998-04-24 1999-04-23 Substituted porphyrins

Publications (1)

Publication Number Publication Date
ATE311206T1 true ATE311206T1 (de) 2005-12-15

Family

ID=22174053

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99919995T ATE311206T1 (de) 1998-04-24 1999-04-23 Substituierte porphyrine

Country Status (10)

Country Link
US (1) US6479477B1 (enExample)
EP (1) EP1071474B1 (enExample)
JP (1) JP4648542B2 (enExample)
AT (1) ATE311206T1 (enExample)
AU (1) AU771259B2 (enExample)
CA (1) CA2329751C (enExample)
DE (1) DE69928655T2 (enExample)
DK (1) DK1071474T3 (enExample)
ES (1) ES2257858T3 (enExample)
WO (1) WO1999055388A1 (enExample)

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US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
IL135949A0 (en) 1997-11-03 2001-05-20 Univ Duke Substituted porphyrins
US6479477B1 (en) 1998-04-24 2002-11-12 Duke University Substituted porphyrins
WO2000009111A2 (en) * 1998-08-11 2000-02-24 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Inhibitors of amyloid formation
IL144503A0 (en) * 1999-01-25 2002-05-23 Nat Jewish Med & Res Center Substituted porphyrins
US6403788B1 (en) 2000-07-11 2002-06-11 Eukarion, Inc. Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species
EP1439842A4 (en) * 2001-06-01 2009-09-02 Nat Jewish Med & Res Center OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE
JP2003012547A (ja) * 2001-06-27 2003-01-15 Meiji Seika Kaisha Ltd インスリン依存性糖尿病の診断剤および治療剤
US20040132706A1 (en) * 2001-10-05 2004-07-08 Daniela Salvemini Composition comprising a catalyst for the dismutation of superoxide and use of the composition for preventing and treating hypotension
EP1513537A4 (en) 2002-06-07 2006-09-06 Univ Duke Substituted porphyrins
ES2285971T3 (es) * 2002-07-15 2008-11-16 Scinopharm Taiwan, Ltd. Procedimiento para la preparacion de imidazo(1,2-a)piridin-3-acetamidas.
GB2397067B (en) 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
US7649091B2 (en) * 2003-06-06 2010-01-19 Eukarion, Inc. Orally bioavailable low molecular weight metalloporphyrins as antioxidants
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US7807825B2 (en) * 2004-02-09 2010-10-05 Duke University Substituted porphyrins
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US7432369B2 (en) 2004-03-29 2008-10-07 Inotek Pharmaceuticals Corporation Pyridyl-substituted porphyrin compounds and methods of use thereof
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US20080289053A1 (en) * 2007-05-15 2008-11-20 The Regents Of The University Of California Methods and systems for identifying modulators of longevity
US20110098262A1 (en) * 2008-01-31 2011-04-28 Yondim Moussa B H Corroles for neuroprotection and neurorescue
KR101646066B1 (ko) 2008-05-23 2016-08-05 내셔날 쥬이쉬 헬스 알킬화 종으로의 노출과 관련된 상해를 치료하는 방법
NZ609924A (en) 2010-10-06 2015-02-27 Aeolus Sciences Inc Porphyrin treatment of neurodegenerative diseases
HK1200728A1 (en) 2011-12-02 2015-08-14 科罗拉多大学董事会,法人团体 Metalloporphyrin neurological treatments
US10646595B2 (en) * 2013-02-12 2020-05-12 The Governing Council Of The University Of Toronto Porphyrin compounds and their use as MRI contrast agents
WO2015034777A1 (en) 2013-09-03 2015-03-12 Biomimetix J.V., Llc Methods of treating biofilms
EP3089666B1 (en) 2013-12-31 2020-08-19 Abbott Diabetes Care Inc. Self-powered analyte sensor and devices using the same
US10064871B2 (en) 2014-01-22 2018-09-04 Biomimetix Jv, Llc Methods of treating skin disorders
WO2015112586A1 (en) 2014-01-22 2015-07-30 Duke University Methods of treating pruritus
KR101894575B1 (ko) 2017-01-03 2018-09-04 주식회사 인트론바이오테크놀로지 돼지 피로부터 유래되지 않은 헴철을 제조할 수 있는 화학적 방법
EP4225759A1 (en) * 2020-10-05 2023-08-16 biolitec Unternehmensbeteiligungs II AG Tetrapyrrole-based compounds and their formulations for anti-microbial therapy

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US2951799A (en) 1957-11-13 1960-09-06 Monsanto Chemicals Photoxidation processes using heterocyclic photosensitizers
DE3464252D1 (en) 1983-06-03 1987-07-23 Hoffmann La Roche Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation
US4963367A (en) 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
GB8429845D0 (en) 1984-11-26 1985-01-03 Efamol Ltd Porphyrins & cancer treatment
US4758422A (en) 1985-01-04 1988-07-19 Salutar Inc. Ferrioxamine paramagnetic contrast agents for MR imaging
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US4746735A (en) 1986-11-21 1988-05-24 The Dow Chemical Company Regiospecific aryl nitration of meso-substituted tetraarylporphyrins
ES2083357T3 (es) 1987-03-14 1996-04-16 Boehringer Ingelheim Int Manganeso-superoxido-dismutasa humana (hmn-sod).
US5227405A (en) 1987-03-31 1993-07-13 Duke University Superoxide dismutase mimic
US5223538A (en) 1987-03-31 1993-06-29 Duke University Superoxide dismutase mimic
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US4851403A (en) 1987-04-21 1989-07-25 Johnson Matthey, Inc. Radiation sensitizers
US4885114A (en) 1987-04-22 1989-12-05 Barnes Engineering Co. Metallized tetra((meso)-5-methyl-2-thiophene)porphines, platinum (5-bromo octaethylporphine) and optical filters containing same
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US5284647A (en) 1988-03-18 1994-02-08 Schering Aktiengesellschaft Mesotetraphenylporphyrin complex compounds, process for their production and pharmaceutical agents containing them
DE3809671A1 (de) 1988-03-18 1989-09-28 Schering Ag Porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5109016A (en) 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
FR2632187B1 (fr) 1988-06-02 1990-09-14 Centre Nat Rech Scient Derives de metalloporphyrines, leur preparation, leur application en therapeutique et leur utilisation pour la preparation de molecules hybrides
US5171680A (en) 1988-06-14 1992-12-15 Chiron Corporation Superoxide dismutase analogs having novel binding properties
EP0414915B1 (en) 1989-03-06 1996-06-12 Suntory Limited New superoxide dismutase
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EP0462836A3 (en) 1990-06-20 1992-08-26 Mitsui Toatsu Chemicals, Inc. Recombinant vector plasmid capable of expressing human manganese superoxide dismutase, and process of producing this enzyme
US5202317A (en) 1990-09-13 1993-04-13 The Regents Of The University Of California Synthetic drug molecules that mimic metalloenzymes
US5217966A (en) 1990-09-13 1993-06-08 The Regents Of The University Of California Synthetic drug molecules that mimic metalloenzymes
WO1992007935A1 (en) 1990-11-01 1992-05-14 The Scripps Research Institute Glycosaminoglycan-targeted fusion proteins, their design, construction and compositions
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FR2676738B1 (fr) 1991-05-22 1995-05-05 Ir2M Nouveau derive organique de metal de transition a structure porphyrinique, composition therapeutique le contenant, en particulier a activite hypoglycemiante.
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US5599924A (en) * 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
DE69330275T2 (de) * 1992-09-03 2001-10-31 The Regents Of The University Of California, Oakland Metallporphyrinzusammensetzungen
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IL135949A0 (en) 1997-11-03 2001-05-20 Univ Duke Substituted porphyrins
US6479477B1 (en) 1998-04-24 2002-11-12 Duke University Substituted porphyrins
IL144503A0 (en) 1999-01-25 2002-05-23 Nat Jewish Med & Res Center Substituted porphyrins
WO2001026655A1 (en) 1999-10-13 2001-04-19 Uab Research Foundation Metalloporphyrin treatment of neurologic disease
CA2412623A1 (en) 2000-06-14 2001-12-20 Brian J. Day Tetrapyrroles

Also Published As

Publication number Publication date
AU771259B2 (en) 2004-03-18
DK1071474T3 (da) 2006-04-10
JP2002512989A (ja) 2002-05-08
CA2329751C (en) 2010-10-12
WO1999055388A9 (en) 2000-01-27
EP1071474A1 (en) 2001-01-31
EP1071474B1 (en) 2005-11-30
WO1999055388A1 (en) 1999-11-04
CA2329751A1 (en) 1999-11-04
DE69928655T2 (de) 2006-08-24
EP1071474A4 (en) 2002-10-24
ES2257858T3 (es) 2006-08-01
JP4648542B2 (ja) 2011-03-09
US6479477B1 (en) 2002-11-12
DE69928655D1 (de) 2006-01-05
AU3758899A (en) 1999-11-16

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties