ATE303381T1 - 6-substituierte 7-heterochinoxalin-carbonsäure- derivate und ihre additionssalze und verfahren zur herstellung von beiden - Google Patents

6-substituierte 7-heterochinoxalin-carbonsäure- derivate und ihre additionssalze und verfahren zur herstellung von beiden

Info

Publication number
ATE303381T1
ATE303381T1 AT00905326T AT00905326T ATE303381T1 AT E303381 T1 ATE303381 T1 AT E303381T1 AT 00905326 T AT00905326 T AT 00905326T AT 00905326 T AT00905326 T AT 00905326T AT E303381 T1 ATE303381 T1 AT E303381T1
Authority
AT
Austria
Prior art keywords
denotes
group
substituted
addition salts
acid derivatives
Prior art date
Application number
AT00905326T
Other languages
German (de)
English (en)
Inventor
Yasuo Takano
Futoshi Shiga
Tsuyoshi Anraku
Kazunori Fukuchi
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Application granted granted Critical
Publication of ATE303381T1 publication Critical patent/ATE303381T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00905326T 1999-02-26 2000-02-25 6-substituierte 7-heterochinoxalin-carbonsäure- derivate und ihre additionssalze und verfahren zur herstellung von beiden ATE303381T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5023899 1999-02-26
JP2000041813A JP2000309586A (ja) 1999-02-26 2000-02-18 ６−置換−７−ヘテロキノキサリンカルボン酸誘導体とその付加塩及びそれらの製造方法
PCT/JP2000/001076 WO2000050420A1 (fr) 1999-02-26 2000-02-25 Derives d'acide 7-heteroquinoxaline carboxilique 6-substitue et leurs sels d'addition, procedes de preparation de ces derives et de leurs sels d'addition

Publications (1)

Publication Number Publication Date
ATE303381T1 true ATE303381T1 (de) 2005-09-15

Family

ID=26390685

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00905326T ATE303381T1 (de) 1999-02-26 2000-02-25 6-substituierte 7-heterochinoxalin-carbonsäure- derivate und ihre additionssalze und verfahren zur herstellung von beiden

Country Status (7)

Country Link
US (1) US6632813B1 (fr)
EP (1) EP1156047B1 (fr)
JP (1) JP2000309586A (fr)
AT (1) ATE303381T1 (fr)
CA (1) CA2364749A1 (fr)
DE (1) DE60022316T2 (fr)
WO (1) WO2000050420A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100113461A1 (en) 2008-10-29 2010-05-06 Gilead Palo Alto, Inc. Substituted heterocyclic compounds
WO2010074807A1 (fr) 2008-10-30 2010-07-01 Gilead Palo Alto, Inc. Dérivés 3, 4-dihydroquinolin-2 (1h) -one utilisés comme modulateurs de canaux sodiques

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268380A (en) * 1988-11-29 1993-12-07 Janssen Pharmaceutica N.V. (1H-azol-1-ylmethyl) substituted quinoline derivatives
AU9049391A (en) 1990-12-20 1992-07-22 Warner-Lambert Company 2-acylamido derivatives of 3,4-dihydro-3-oxo-quinoxaline having pharmaceutical activity
AU6690394A (en) * 1993-05-12 1994-12-12 Yamanouchi Pharmaceutical Co., Ltd. Imidazolylquinoxalinedione derivative and pharmaceutical composition thereof
JPH07165756A (ja) * 1993-12-14 1995-06-27 Yamanouchi Pharmaceut Co Ltd ヒドロキシキノキサリンジオン誘導体
DE19624808A1 (de) * 1996-06-21 1998-01-02 Basf Ag Pyrrolylchinoxalindione, ihre Herstellung und Verwendung
WO1999011632A1 (fr) * 1997-09-01 1999-03-11 Kyorin Pharmaceutical Co., Ltd. Derives d'acide quinoxalinecarboxylique disubstitues en position 6,7-asymetrique, sels d'addition de ces derives, et procedes de preparation de ces derives et de ces sels
JPH11130756A (ja) * 1997-09-01 1999-05-18 Kyorin Pharmaceut Co Ltd ７−アリールキノキサリンカルボン酸誘導体とその付加塩及びそれらの製造方法

Also Published As

Publication number Publication date
DE60022316D1 (de) 2005-10-06
WO2000050420A1 (fr) 2000-08-31
DE60022316T2 (de) 2006-06-29
EP1156047B1 (fr) 2005-08-31
EP1156047A1 (fr) 2001-11-21
US6632813B1 (en) 2003-10-14
JP2000309586A (ja) 2000-11-07
EP1156047A4 (fr) 2002-05-15
CA2364749A1 (fr) 2000-08-31

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Legal Events

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