ATE302596T1 - Verfahren zur herstellung von zur agglomeration geeigneten partikeln - Google Patents

Verfahren zur herstellung von zur agglomeration geeigneten partikeln

Info

Publication number
ATE302596T1
ATE302596T1 AT00913218T AT00913218T ATE302596T1 AT E302596 T1 ATE302596 T1 AT E302596T1 AT 00913218 T AT00913218 T AT 00913218T AT 00913218 T AT00913218 T AT 00913218T AT E302596 T1 ATE302596 T1 AT E302596T1
Authority
AT
Austria
Prior art keywords
agglomeration
particles suitable
producing particles
producing
particles
Prior art date
Application number
AT00913218T
Other languages
English (en)
Inventor
Tsong-Toh Yang
Stephen K C Yu
Charles G Eckhart
Michael B Mitchell
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE302596T1 publication Critical patent/ATE302596T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Silicon Compounds (AREA)
AT00913218T 1999-01-28 2000-01-27 Verfahren zur herstellung von zur agglomeration geeigneten partikeln ATE302596T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23948699A 1999-01-28 1999-01-28
PCT/US2000/000496 WO2000044352A1 (en) 1999-01-28 2000-01-27 Method of preparing particles for agglomeration

Publications (1)

Publication Number Publication Date
ATE302596T1 true ATE302596T1 (de) 2005-09-15

Family

ID=22902364

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00913218T ATE302596T1 (de) 1999-01-28 2000-01-27 Verfahren zur herstellung von zur agglomeration geeigneten partikeln

Country Status (13)

Country Link
EP (2) EP1516614A1 (de)
JP (2) JP3946445B2 (de)
CN (2) CN101480376B (de)
AR (1) AR022695A1 (de)
AT (1) ATE302596T1 (de)
AU (1) AU3470000A (de)
CA (1) CA2360649C (de)
DE (1) DE60022163T2 (de)
DK (1) DK1146859T3 (de)
ES (1) ES2248057T3 (de)
HK (1) HK1037137A1 (de)
WO (1) WO2000044352A1 (de)
ZA (1) ZA200104005B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR036358A1 (es) * 2001-08-28 2004-09-01 Schering Corp Un inhalador de dosis medidas que contiene una formulacion de suspension en aerosol para inhalacion, un proceso para la produccion de la formulacion, el producto y el uso de una formulacion para la manufactura de un medicamento de asma
JP2005519129A (ja) * 2002-03-05 2005-06-30 クリーブランド ステート ユニバーシティー エアロゾル薬物送達のための凝集粒子
EP1667687A1 (de) * 2003-09-26 2006-06-14 Schering Corporation Behandlung von lungenerkrankung
BRPI0416534A (pt) * 2003-12-04 2007-01-09 Pfizer Prod Inc composições multiparticuladas com estabilidade melhorada
CN104177448A (zh) 2005-02-10 2014-12-03 葛兰素集团有限公司 使用预分选技术制备乳糖的方法以及由此形成的药物制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9101090D0 (sv) * 1991-04-11 1991-04-11 Astra Ab Process for conditioning of water-soluble substances
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
DK1393721T3 (da) * 1997-03-20 2009-03-30 Schering Corp Doseringsform af pulveragglomerater
GB9808470D0 (en) * 1998-04-22 1998-06-17 Smithkline Beecham Plc Novel process and apparatus

Also Published As

Publication number Publication date
DK1146859T3 (da) 2005-12-19
JP3946445B2 (ja) 2007-07-18
EP1146859B1 (de) 2005-08-24
ES2248057T3 (es) 2006-03-16
DE60022163T2 (de) 2006-04-13
WO2000044352A1 (en) 2000-08-03
CN101480376B (zh) 2013-01-16
CN1341013A (zh) 2002-03-20
DE60022163D1 (de) 2005-09-29
JP2002535352A (ja) 2002-10-22
AR022695A1 (es) 2002-09-04
AU3470000A (en) 2000-08-18
CA2360649A1 (en) 2000-08-03
HK1037137A1 (en) 2002-02-01
EP1146859A1 (de) 2001-10-24
JP2006257103A (ja) 2006-09-28
CA2360649C (en) 2005-09-20
EP1516614A1 (de) 2005-03-23
ZA200104005B (en) 2002-08-16
CN100467014C (zh) 2009-03-11
CN101480376A (zh) 2009-07-15

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