ATE299711T1 - Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen - Google Patents

Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen

Info

Publication number
ATE299711T1
ATE299711T1 AT98918742T AT98918742T ATE299711T1 AT E299711 T1 ATE299711 T1 AT E299711T1 AT 98918742 T AT98918742 T AT 98918742T AT 98918742 T AT98918742 T AT 98918742T AT E299711 T1 ATE299711 T1 AT E299711T1
Authority
AT
Austria
Prior art keywords
tolerance
mucosatal
compositions containing
immunological tolerance
binding compounds
Prior art date
Application number
AT98918742T
Other languages
German (de)
English (en)
Inventor
Jacob Sten Petersen
Original Assignee
Jacob Sten Petersen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jacob Sten Petersen filed Critical Jacob Sten Petersen
Application granted granted Critical
Publication of ATE299711T1 publication Critical patent/ATE299711T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98918742T 1997-04-23 1998-04-23 Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen ATE299711T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4418297P 1997-04-23 1997-04-23
US4418497P 1997-04-23 1997-04-23
PCT/US1998/008361 WO1998047529A1 (en) 1997-04-23 1998-04-23 Combinations of antigen and mucosal binding component for inducing specific immunological tolerance

Publications (1)

Publication Number Publication Date
ATE299711T1 true ATE299711T1 (de) 2005-08-15

Family

ID=26721263

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98918742T ATE299711T1 (de) 1997-04-23 1998-04-23 Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen

Country Status (8)

Country Link
US (1) US7097845B2 (OSRAM)
EP (1) EP0977586B1 (OSRAM)
JP (1) JP2001523249A (OSRAM)
AT (1) ATE299711T1 (OSRAM)
AU (1) AU7161098A (OSRAM)
DE (1) DE69830900T2 (OSRAM)
DK (1) DK0977586T3 (OSRAM)
WO (1) WO1998047529A1 (OSRAM)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9800487D0 (en) * 1998-01-09 1998-03-04 Oratol Limited Therapies
WO2001022995A1 (en) * 1999-09-30 2001-04-05 Novo Nordisk A/S A method for preparing conjugates between an antigen and mucosal binding component
AU781909B2 (en) * 2000-01-25 2005-06-23 Board Of Regents Of The University Of Nebraska, The Pre-transplant accommodated organs resistant to anti-donor immunity
US7897575B2 (en) * 2000-05-24 2011-03-01 The United States Of America As Represented By The Department Of Health And Human Services Treatment and prevention of vascular dementia
CA2447795A1 (en) * 2001-05-23 2002-11-28 Duotol Ab Suppression of allergic reactions by transdermal administration of allergens in conjunction with or conjugated to toxin subunits or fragments thereof
EP2107069B1 (en) 2003-08-05 2013-01-16 Novo Nordisk A/S Novel insulin derivatives
US20090074882A1 (en) 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
JP5552046B2 (ja) 2007-06-13 2014-07-16 ノボ・ノルデイスク・エー／エス インスリン誘導体を含有する薬学的製剤
KR20110085985A (ko) 2008-10-30 2011-07-27 노보 노르디스크 에이/에스 하루 한번 주사 빈도보다 적은 인슐린 주사를 사용한 진성 당뇨병의 치료
JP6249773B2 (ja) * 2010-05-10 2017-12-20 ノヴォ ノルディスク アー／エス インスリン−亜鉛錯体の調製方法
BR112013010345A2 (pt) 2010-10-27 2017-07-25 Novo Nordisk As tratamento de diabetes melitus usando as injeções de insulina administradas com intervalos de variação da injeção
JP2016519127A (ja) 2013-04-30 2016-06-30 ノヴォ ノルディスク アー／エス 新規投与レジメン
US12605432B2 (en) 2014-06-04 2026-04-21 Diamyd Medical Ab Combinations for antigen based therapy
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation
WO2022177890A1 (en) * 2021-02-16 2022-08-25 Applied Molecular Transport Inc. Solid oral compositions with zinc

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666837A (en) 1982-05-24 1987-05-19 Smithkline-Rit DNA sequences, recombinant DNA molecules and processes for producing the A and B subunits of cholera toxin and preparations containing so-obtained subunit or subunits
DK97986A (da) * 1985-03-08 1986-09-09 Takeda Chemical Industries Ltd Middel til inhibering af fordoejelse af sakkarid
US5399347A (en) 1987-06-24 1995-03-21 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
DE3856566T2 (de) 1987-06-24 2004-06-24 Brigham And Women's Hospital, Boston Behandlung von Autoimmun-Erkrankungen durch orale Verabreichung von Autoantigenen
JPH02235823A (ja) 1989-03-09 1990-09-18 Watanabe Mitsuko 抗アレルギー剤
JP2891485B2 (ja) 1989-09-25 1999-05-17 科学技術振興事業団 移植拒絶反応抑制剤
WO1991008760A1 (en) 1989-12-20 1991-06-27 Brigham And Women's Hospital Improved treatment of autoimmune diseases by aerosol administration of auto antigens
DE69127470T2 (de) 1990-03-02 1998-02-19 Autoimmune Inc Verstärkung der unterdrückungsregulation von autoimmunkrankheiten durch orale oder enterale verabreichung von autoantigenen
CA2050425A1 (en) 1990-09-03 1992-03-04 Yoshiaki Uda Pharmaceutical composition and its mucous use
JP3198390B2 (ja) * 1990-09-03 2001-08-13 武田薬品工業株式会社 経粘膜用製剤
IL99864A (en) 1990-10-31 2000-11-21 Autoimmune Inc Compositions for suppressing transplant rejection in mammals which contain tissue donor derived MHC antigens
ES2190784T3 (es) 1992-02-28 2003-08-16 Autoimmune Inc Supresion de enfermedades autoinmunes por antigenos espectadores.
US5453272A (en) 1992-10-02 1995-09-26 Alberta Research Council Lectin derived carbohydrate binding-peptide
JP3109328B2 (ja) 1993-05-19 2000-11-13 ウシオ電機株式会社 加熱定着装置
WO1994027634A1 (en) 1993-06-02 1994-12-08 Institute For Child Health Research Cryptic peptides for use in inducing immunologic tolerance
US5681571A (en) * 1993-10-08 1997-10-28 Duotol Ab Immunological tolerance-inducing agent
JP2847696B2 (ja) * 1994-05-11 1999-01-20 田辺製薬株式会社 プロピオフェノン誘導体及びその製法
JP2847695B2 (ja) * 1994-05-11 1999-01-20 田辺製薬株式会社 血糖降下剤
IL111866A (en) 1994-12-04 2005-03-20 Yeda Res & Dev Pharmaceutical compositions comprising the b-oligomer of pertussis toxin
JPH10512554A (ja) 1995-01-10 1998-12-02 ファイブローゲン，インコーポレーテッド 免疫系媒介疾患の治療のためのコラーゲンに基づく方法および製剤
AU6113896A (en) 1995-06-05 1996-12-24 Brigham And Women's Hospital Use of oral tolerance to suppress both th1 and th2 immune re sponses and to suppress antibody production
GB9513733D0 (en) * 1995-07-05 1995-09-06 Univ Bristol Therapeutic agents

Also Published As

Publication number Publication date
DE69830900D1 (de) 2005-08-25
JP2001523249A (ja) 2001-11-20
US20020119159A1 (en) 2002-08-29
DE69830900T2 (de) 2006-05-24
WO1998047529A1 (en) 1998-10-29
AU7161098A (en) 1998-11-13
EP0977586A1 (en) 2000-02-09
EP0977586B1 (en) 2005-07-20
DK0977586T3 (da) 2005-12-05
US7097845B2 (en) 2006-08-29

Similar Documents

Publication Publication Date Title
DE69830900D1 (de) Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen
DE69837324D1 (de) Behandlung der multiplen sklerose durch einnahme von copolymer-1
HU9303357D0 (en) Pharmaceutical composition containing well-defined lipide-systhem
MX9702865A (es) Agentes estrogenicos.
FI972945A0 (fi) Antigeenien antamiseen soveltuvia koostumuksia
TW272195B (OSRAM)
ATE231839T1 (de) Polyaromatische antivirale zusammensetzungen
WO1998046270A3 (en) Polymeric conjugates polyvalently presenting an agent for therapy
PL316942A1 (en) Novel pharmaceutic compositions based on taxoides
DK0588578T3 (da) Immunogener
FR2703051B1 (fr) Nouvelles pyridothiadiazines, leurs procédés de préparation, et les compositions pharmaceutiques qui les contiennent.
DK0789590T3 (da) Chitosaninduceret immunforstærkning
ATE229340T1 (de) Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen
BR0208017A (pt) Combinação compreendendo combretastatina e agentes anticâncer
DK0712311T3 (da) Antiglucocorticoidsteroider til behandling af angstlidelser
KR960702320A (ko) 감마 인터페론의 안정한 액체 조성물 (Stable Liquid Compositions of Gamma Interferon)
DK0584247T3 (da) Sammensætninger til behandling af kronisk træthedssyndrom
DE60113664D1 (de) Zusammensetzung zur behandlung von herzinsuffizienz
ES2182975T3 (es) Nueva quimica heterociclica.
ATE231728T1 (de) Pharmazeutische zusammensetzung enthaltend interferon-gamma stimulatoren
FR2704547B1 (fr) Nouveaux composés pyrrolopyraziniques, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
ATE141248T1 (de) Neue bis-phenyl-hexene
BG101163A (bg) 8-флуоро-антрациклини, процеси за тяхното получаване и фармацевтични състави съдържащи ги
DK0817643T3 (da) Forbindelser og præparater til administration af aktive midler
BG102083A (en) Compositions and methods for the detection and treatment of aids

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification

Ref document number: 0977586

Country of ref document: EP