ATE229340T1 - Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen - Google Patents

Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen

Info

Publication number
ATE229340T1
ATE229340T1 AT96920364T AT96920364T ATE229340T1 AT E229340 T1 ATE229340 T1 AT E229340T1 AT 96920364 T AT96920364 T AT 96920364T AT 96920364 T AT96920364 T AT 96920364T AT E229340 T1 ATE229340 T1 AT E229340T1
Authority
AT
Austria
Prior art keywords
related methods
relaxing factor
factor
relaxin
analogs
Prior art date
Application number
AT96920364T
Other languages
English (en)
Inventor
Christian Schwabe
Elaine Unemori
Original Assignee
Connective Therapeutics Inc
Univ South Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connective Therapeutics Inc, Univ South Carolina filed Critical Connective Therapeutics Inc
Application granted granted Critical
Publication of ATE229340T1 publication Critical patent/ATE229340T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT96920364T 1995-06-07 1996-05-16 Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen ATE229340T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/484,219 US5911997A (en) 1995-06-07 1995-06-07 Relaxin-like factor and methods and uses thereof
PCT/US1996/007399 WO1996040186A1 (en) 1995-06-07 1996-05-16 Relaxin-like factor and methods and uses thereof

Publications (1)

Publication Number Publication Date
ATE229340T1 true ATE229340T1 (de) 2002-12-15

Family

ID=23923245

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96920364T ATE229340T1 (de) 1995-06-07 1996-05-16 Relaxinartiger faktor und damit zusammenhängende verfahren und verwendungen

Country Status (9)

Country Link
US (2) US5911997A (de)
EP (1) EP0831871B1 (de)
JP (1) JP3830520B2 (de)
AT (1) ATE229340T1 (de)
AU (1) AU709115B2 (de)
CA (1) CA2224080C (de)
DE (1) DE69625354T2 (de)
ES (1) ES2188763T3 (de)
WO (1) WO1996040186A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69624925T2 (de) * 1995-08-15 2003-09-04 Connetics Corp Verwendung von relaxin zur stimulierung der angiogenese
DE19641378C1 (de) * 1996-09-27 1998-04-02 Ihf Inst Fuer Hormon Und Fortp Diagnosehilfe sowie Verfahren zum Nachweis der Trächtigkeit von Wiederkäuern
GB9717652D0 (en) * 1997-08-20 1997-10-22 Nycomed Imaging As Method
AUPR814401A0 (en) 2001-10-08 2001-11-01 Howard Florey Institute Of Experimental Physiology And Medicine Human 3 relaxin
US20050186526A1 (en) * 2002-11-01 2005-08-25 Bas Medical, Inc. Methods and systems for enabling and stabilizing tooth movement
AU2003903124A0 (en) * 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
US7878978B2 (en) * 2004-03-18 2011-02-01 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Use of relaxin to increase arterial compliance
US7553813B2 (en) * 2004-04-30 2009-06-30 Corthera, Inc. Methods and compositions for control of fetal growth via modulation of relaxin
US20060052304A1 (en) * 2004-09-02 2006-03-09 Bas Medical, Inc. Method for remodeling bone and related sutures
EP1984016A1 (de) * 2006-02-17 2008-10-29 Associazione Foresta Per La Ricerca Nella Riproduzione Umana Verwendung von insulin-artigem faktor 3 zur behandlung von osteoporose und knochenerkrankungen
CA2742792A1 (en) * 2008-11-24 2010-05-27 University Of Pittsburgh Of The Commonwealth System Of Higher Education Prediction and prevention of preeclampsia
BR112013003522B1 (pt) 2010-08-17 2021-05-25 Ambrx, Inc. polipeptídeos relaxina modificados compreendendo um aminoácido não codificado naturalmente, seu método de preparação e seu uso, bem como ácido nucleico e célula hospedeira
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
BR112014002124A2 (pt) * 2011-08-04 2017-02-21 Pharis Biotec Gmbh processo para preparar relaxina-2 humana
WO2013177529A1 (en) * 2012-05-24 2013-11-28 Angion Biomedica Corp. Relaxin-like compounds and uses thereof
US9393288B2 (en) 2012-05-29 2016-07-19 The University Of Vermont And State Agricultural College Methods of treating diseases associated with PPARγ
US20160060322A1 (en) * 2012-09-10 2016-03-03 Angion Biomedica Corp. Relaxin-like peptides and uses thereof
JP6822839B2 (ja) 2013-09-13 2021-01-27 ザ・スクリップス・リサーチ・インスティテュート 修飾された治療剤、及びその組成物
CN106456589B (zh) 2013-12-18 2020-07-07 斯克利普斯研究所 修饰的治疗剂、订合的肽脂质缀合物及其组合物
MA41794A (fr) * 2015-03-18 2018-01-23 The California Institute For Biomedical Res Agents thérapeutiques modifiés et compositions associées
DK3387019T3 (da) 2015-12-09 2022-01-10 Scripps Research Inst Relaxin-immunoglobulinfusionsproteiner og anvendelsesfremgangsmåder
BR112019016139A2 (pt) 2017-02-08 2020-04-07 Bristol-Myers Squibb Company polipeptídio de relaxina modificada compreendendo um melhorador farmacocinético e usos do mesmo

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287820B1 (de) * 1982-08-12 1992-07-08 Howard Florey Institute Of Experimental Physiology And Medicine Analoge des humanen Relaxins
US4835251A (en) * 1986-06-23 1989-05-30 Genetech, Inc. Method of chain combination
US5478807A (en) * 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy

Also Published As

Publication number Publication date
CA2224080A1 (en) 1996-12-19
WO1996040186A1 (en) 1996-12-19
AU5869996A (en) 1996-12-30
US20030158376A1 (en) 2003-08-21
DE69625354T2 (de) 2003-10-30
EP0831871A1 (de) 1998-04-01
DE69625354D1 (de) 2003-01-23
ES2188763T3 (es) 2003-07-01
US6949506B2 (en) 2005-09-27
US5911997A (en) 1999-06-15
JPH11512072A (ja) 1999-10-19
JP3830520B2 (ja) 2006-10-04
EP0831871A4 (de) 1999-03-03
CA2224080C (en) 2010-07-27
EP0831871B1 (de) 2002-12-11
AU709115B2 (en) 1999-08-19

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