ATE299704T1 - Warmgeformte feste arzneizusammensetzung zur gesteuerten wirkstoffabgabe von perindopril - Google Patents

Warmgeformte feste arzneizusammensetzung zur gesteuerten wirkstoffabgabe von perindopril

Info

Publication number
ATE299704T1
ATE299704T1 AT01989653T AT01989653T ATE299704T1 AT E299704 T1 ATE299704 T1 AT E299704T1 AT 01989653 T AT01989653 T AT 01989653T AT 01989653 T AT01989653 T AT 01989653T AT E299704 T1 ATE299704 T1 AT E299704T1
Authority
AT
Austria
Prior art keywords
perindopril
hot
medicinal composition
controlled delivery
formed solid
Prior art date
Application number
AT01989653T
Other languages
English (en)
Inventor
Patrick Wuthrich
Herve Rolland
Gilles Briault
Gerald Pichon
Francois Tharrault
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of ATE299704T1 publication Critical patent/ATE299704T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
AT01989653T 2000-12-26 2001-12-21 Warmgeformte feste arzneizusammensetzung zur gesteuerten wirkstoffabgabe von perindopril ATE299704T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0017013A FR2818550B1 (fr) 2000-12-26 2000-12-26 Composition pharmaceutique solide thermoformable pour la liberation controle de perindopril
PCT/FR2001/004133 WO2002051407A1 (fr) 2000-12-26 2001-12-21 Composition pharmaceutique solide thermoformable pour la liberation controlee de perindopril

Publications (1)

Publication Number Publication Date
ATE299704T1 true ATE299704T1 (de) 2005-08-15

Family

ID=8858188

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01989653T ATE299704T1 (de) 2000-12-26 2001-12-21 Warmgeformte feste arzneizusammensetzung zur gesteuerten wirkstoffabgabe von perindopril

Country Status (26)

Country Link
US (1) US20040115227A1 (de)
EP (1) EP1345605B1 (de)
JP (1) JP2004518666A (de)
KR (1) KR100542473B1 (de)
CN (1) CN1218696C (de)
AR (1) AR031972A1 (de)
AT (1) ATE299704T1 (de)
AU (1) AU2002228118B2 (de)
BR (1) BR0116536A (de)
CA (1) CA2432896A1 (de)
CZ (1) CZ297796B6 (de)
DE (1) DE60112117T2 (de)
DK (1) DK1345605T3 (de)
EA (1) EA005139B1 (de)
ES (1) ES2244672T3 (de)
FR (1) FR2818550B1 (de)
HK (1) HK1063739A1 (de)
HU (1) HU230249B1 (de)
MX (1) MXPA03005792A (de)
NO (1) NO333590B1 (de)
NZ (1) NZ526405A (de)
PL (1) PL203836B1 (de)
PT (1) PT1345605E (de)
SK (1) SK286920B6 (de)
WO (1) WO2002051407A1 (de)
ZA (1) ZA200304405B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK50252005A3 (sk) * 2005-03-22 2006-10-05 Vúlm, A.S. Farmaceutický prípravok obsahujúci perindopril erbumín, spôsob jeho prípravy a stabilizácie
BRPI0615607A2 (pt) * 2005-08-30 2011-05-24 Lek Pharmaceuticals composição farmacêutica compreendendo perindopril ou seus sais
BR112014004753A2 (pt) * 2011-08-30 2017-03-28 Univ Gent formulação de liberação de multicamadas
RU2670447C2 (ru) * 2016-11-17 2018-10-23 Общество с ограниченной ответственностью "Изварино Фарма" Пероральная твердая лекарственная форма с микофенольной кислотой или ее солью для использования в качестве иммунодепрессанта для лечения или предупреждения отторжения трансплантата органа или ткани и способ ее получения

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002776A (en) * 1983-12-22 1991-03-26 Elan Corporation, Plc Controlled absorption diltiazem formulations
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
US5589499A (en) * 1992-11-25 1996-12-31 Weth; Gosbert Dopaminergic agents for the treatment of cerebral and peripheral blood flow disorders
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19724696A1 (de) * 1997-06-12 1998-12-24 Hexal Ag Pharmazeutische Zubereitung mit drei Pelletarten
GB9910773D0 (en) * 1999-05-11 1999-07-07 West Pharm Serv Drug Res Ltd Novel single unit coated dosage forms that can be used to minimise the effect of food on the absorption of drugs from the gastrointestinal tract
FR2795326B1 (fr) * 1999-06-28 2001-08-31 Adir Composition pharmaceutique solide thermoformable a liberation controlee

Also Published As

Publication number Publication date
KR20030064877A (ko) 2003-08-02
SK286920B6 (sk) 2009-07-06
DK1345605T3 (da) 2005-10-10
CN1218696C (zh) 2005-09-14
HU230249B1 (hu) 2015-11-30
EA005139B1 (ru) 2004-12-30
WO2002051407A1 (fr) 2002-07-04
HK1063739A1 (en) 2005-01-14
NZ526405A (en) 2004-12-24
PL361663A1 (en) 2004-10-04
DE60112117D1 (de) 2005-08-25
CZ20032008A3 (cs) 2004-01-14
CZ297796B6 (cs) 2007-03-28
BR0116536A (pt) 2003-10-21
NO20032738L (no) 2003-06-16
CA2432896A1 (fr) 2002-07-04
HUP0302524A3 (en) 2007-09-28
AU2002228118B2 (en) 2006-04-27
EP1345605A1 (de) 2003-09-24
NO333590B1 (no) 2013-07-15
FR2818550A1 (fr) 2002-06-28
AR031972A1 (es) 2003-10-08
US20040115227A1 (en) 2004-06-17
DE60112117T2 (de) 2006-06-01
NO20032738D0 (no) 2003-06-16
JP2004518666A (ja) 2004-06-24
FR2818550B1 (fr) 2003-02-07
MXPA03005792A (es) 2003-09-10
HUP0302524A2 (hu) 2003-12-29
PT1345605E (pt) 2005-11-30
ES2244672T3 (es) 2005-12-16
KR100542473B1 (ko) 2006-01-11
EP1345605B1 (de) 2005-07-20
SK9432003A3 (en) 2003-12-02
PL203836B1 (pl) 2009-11-30
ZA200304405B (en) 2004-06-25
EA200300664A1 (ru) 2003-12-25
CN1482909A (zh) 2004-03-17

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