ATE297461T1 - Reguliertes autokrines wachstum von säugerzellen - Google Patents

Reguliertes autokrines wachstum von säugerzellen

Info

Publication number
ATE297461T1
ATE297461T1 AT96924714T AT96924714T ATE297461T1 AT E297461 T1 ATE297461 T1 AT E297461T1 AT 96924714 T AT96924714 T AT 96924714T AT 96924714 T AT96924714 T AT 96924714T AT E297461 T1 ATE297461 T1 AT E297461T1
Authority
AT
Austria
Prior art keywords
growth
host cells
regulated
autocrine growth
mammal cells
Prior art date
Application number
AT96924714T
Other languages
English (en)
Inventor
Sybille Marie Hunt
Peter Philip Gray
Merilyn Joy Sleigh
Original Assignee
Unisearch Ltd
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unisearch Ltd, Commw Scient Ind Res Org filed Critical Unisearch Ltd
Application granted granted Critical
Publication of ATE297461T1 publication Critical patent/ATE297461T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
AT96924714T 1995-07-26 1996-07-26 Reguliertes autokrines wachstum von säugerzellen ATE297461T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPN4422A AUPN442295A0 (en) 1995-07-26 1995-07-26 Regulated autocrine growth of mammalian cells
PCT/AU1996/000472 WO1997005240A1 (en) 1995-07-26 1996-07-26 Regulated autocrine growth of mammalian cells

Publications (1)

Publication Number Publication Date
ATE297461T1 true ATE297461T1 (de) 2005-06-15

Family

ID=3788757

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96924714T ATE297461T1 (de) 1995-07-26 1996-07-26 Reguliertes autokrines wachstum von säugerzellen

Country Status (7)

Country Link
US (2) US6340574B1 (de)
EP (1) EP0843722B1 (de)
JP (1) JP3961567B2 (de)
AT (1) ATE297461T1 (de)
AU (1) AUPN442295A0 (de)
DE (1) DE69634819T2 (de)
WO (1) WO1997005240A1 (de)

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US6475725B1 (en) 1997-06-20 2002-11-05 Baxter Aktiengesellschaft Recombinant cell clones having increased stability and methods of making and using the same
AT407255B (de) * 1997-06-20 2001-02-26 Immuno Ag Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons
AT409379B (de) 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen
EP1200561B1 (de) * 1999-08-05 2006-06-14 Baxter Aktiengesellschaft Rekombinanter stabiler zellklon, seine herstellung und verwendung
PT1210411E (pt) 1999-08-25 2006-12-29 Immunex Corp Composições e métodos para cultura celular melhorada
EP1754784A3 (de) * 1999-09-03 2007-02-28 Applied Research Systems ARS Holding N.V. Verfahren zur Produktion eines heterologen sezernierten Proteins aus auf Mikroträgern gewachsenen Cho-Zellen
UA74557C2 (en) * 1999-09-03 2006-01-16 Applied Research Systems A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
DK2287288T3 (da) 2002-07-09 2013-01-07 Baxter Int Medium frit for animalsk protein til dyrkning af celler
CU23097A1 (es) 2002-10-23 2005-11-18 Centro Inmunologia Molecular Método para la obtención de líneas celulares en medio libre de proteína y líneas celulares obtenidas por este método
US8058156B2 (en) * 2004-07-20 2011-11-15 Applied Materials, Inc. Plasma immersion ion implantation reactor having multiple ion shower grids
US20060094104A1 (en) 2004-10-29 2006-05-04 Leopold Grillberger Animal protein-free media for cultivation of cells
TWI406870B (zh) * 2005-02-21 2013-09-01 Chugai Pharmaceutical Co Ltd A method of making a protein using hamster IGF-1
LT1974014T (lt) 2006-01-04 2017-11-27 Baxalta Incorporated Ląstelių kultūros terpė be oligopeptidų
EP1970441A1 (de) * 2007-03-06 2008-09-17 BioAlliance Pharma Plasmid mit einer Sequenz, die eine Disintegrin-Domäne von Metargidin (RDD) kodiert
WO2008118959A1 (en) * 2007-03-26 2008-10-02 The University Of Chicago Immunoassays and characterization of biomolecular interactions using self- assembled monolayers
WO2009115495A1 (de) * 2008-03-19 2009-09-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Methode zur steigerung der reklonierungseffizienz
US20110016548A1 (en) * 2009-07-16 2011-01-20 University Of Southern California Control of endogenous dnmt1 gene expression by exogenous binary regulatory systems
WO2012023085A1 (en) 2010-08-20 2012-02-23 Wyeth Llc Cell culture of growth factor-free adapted cells
CN103768611B (zh) * 2012-10-19 2016-12-28 河南师范大学 植物源性醇溶蛋白共轭ZnO/Cd(OH)C1纳米抗癌药物及其制备方法
CA2904167A1 (en) * 2013-03-08 2014-09-12 Neuclone Biologics Pty Ltd Cell culture media composition and methods of producing thereof
SG11201506926SA (en) 2013-03-08 2015-09-29 Neuclone Biolog Pty Ltd A cell expression system
TWI656839B (zh) 2013-03-15 2019-04-21 健臻公司 高密度細胞儲存方法
RU2723129C2 (ru) 2014-09-18 2020-06-08 Джензим Корпорейшн Способы создания банков клеток со сверхвысокой плотностью
JP6245299B2 (ja) * 2016-04-27 2017-12-13 バクスアルタ ゲーエムベーハー 組換え安定細胞クローン、その産生およびその使用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0136907A3 (de) * 1983-10-03 1986-12-30 Genentech, Inc. Xenogeneisches Expressionskontrollsystem, Verfahren zu dessen Verwendung, dieses enthaltende Expressionsvektoren, mit denselben transformierte Zellen und daraus hergestellte heterolose Proteine
ATE89314T1 (de) * 1985-02-13 1993-05-15 Scios Nova Inc Menschlicher metallothionein ii-promotor in saeugetierexpressionssystemen.
IL87737A (en) * 1987-09-11 1993-08-18 Genentech Inc Method for culturing polypeptide factor dependent vertebrate recombinant cells
AU612404B2 (en) * 1987-09-11 1991-07-11 Genentech Inc. Method for increasing the expression of polypeptides in recombinant cell culture
WO1991003554A1 (en) * 1989-09-01 1991-03-21 Genentech, Inc. Cells transfected with nucleic acid encoding gtp
CA2123430C (en) 1991-12-06 2004-02-10 Cornelia M. Gorman Prohormone convertase transformed cells
US5262308A (en) * 1992-01-28 1993-11-16 Thomas Jefferson University Cell lines which constitutively express IGF-1 and IGF-1 R
GB9216151D0 (en) * 1992-07-29 1992-09-09 Ici Plc Containment of plant germplasm
US5856179A (en) * 1994-03-10 1999-01-05 Genentech, Inc. Polypeptide production in animal cell culture
US5723333A (en) * 1995-02-10 1998-03-03 Regents Of The University Of California Human pancreatic cell lines: developments and uses

Also Published As

Publication number Publication date
US6340574B1 (en) 2002-01-22
DE69634819T2 (de) 2006-03-23
WO1997005240A1 (en) 1997-02-13
JP3961567B2 (ja) 2007-08-22
AUPN442295A0 (en) 1995-08-17
JPH11509734A (ja) 1999-08-31
EP0843722B1 (de) 2005-06-08
EP0843722A1 (de) 1998-05-27
EP0843722A4 (de) 2002-05-02
US20020102650A1 (en) 2002-08-01
DE69634819D1 (de) 2005-07-14
US6797515B2 (en) 2004-09-28

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