ATE288445T1 - Herstellung von n-(n-(3,3-dimethylbutyl)-l-alpha- aspartyl)-l-phenylalanin-1-methylester durch verwendung vom l-alpha-aspartyl-l-phenylalanin-1- methylester als vorläufer - Google Patents
Herstellung von n-(n-(3,3-dimethylbutyl)-l-alpha- aspartyl)-l-phenylalanin-1-methylester durch verwendung vom l-alpha-aspartyl-l-phenylalanin-1- methylester als vorläuferInfo
- Publication number
- ATE288445T1 ATE288445T1 AT01937548T AT01937548T ATE288445T1 AT E288445 T1 ATE288445 T1 AT E288445T1 AT 01937548 T AT01937548 T AT 01937548T AT 01937548 T AT01937548 T AT 01937548T AT E288445 T1 ATE288445 T1 AT E288445T1
- Authority
- AT
- Austria
- Prior art keywords
- aspartyl
- phenylalanine
- alpha
- methyl ester
- dimethylbutyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Seasonings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20510500P | 2000-05-18 | 2000-05-18 | |
| PCT/US2001/016146 WO2001087927A2 (en) | 2000-05-18 | 2001-05-18 | gYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING L-α-ASPARTYL-L-PHENYLALANINE 1-METHYL ESTER PRECURSORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE288445T1 true ATE288445T1 (de) | 2005-02-15 |
Family
ID=22760810
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03023604T ATE310013T1 (de) | 2000-05-18 | 2001-05-18 | Herstellung von n-(n-(3,3-dimethylbutyl)-l-alpha- aspartyl)-l-phenylalanin-1-methylester durch verwendung vom l-alpha-aspartyl-l-phenylalanin-1- methylester als vorläufer |
| AT01937548T ATE288445T1 (de) | 2000-05-18 | 2001-05-18 | Herstellung von n-(n-(3,3-dimethylbutyl)-l-alpha- aspartyl)-l-phenylalanin-1-methylester durch verwendung vom l-alpha-aspartyl-l-phenylalanin-1- methylester als vorläufer |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03023604T ATE310013T1 (de) | 2000-05-18 | 2001-05-18 | Herstellung von n-(n-(3,3-dimethylbutyl)-l-alpha- aspartyl)-l-phenylalanin-1-methylester durch verwendung vom l-alpha-aspartyl-l-phenylalanin-1- methylester als vorläufer |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6642406B2 (de) |
| EP (1) | EP1280818B1 (de) |
| AT (2) | ATE310013T1 (de) |
| AU (1) | AU2001263267A1 (de) |
| DE (2) | DE60108739T2 (de) |
| ES (2) | ES2233644T3 (de) |
| WO (1) | WO2001087927A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004094453A2 (en) * | 2003-04-17 | 2004-11-04 | The Nutrasweet Company | Filtration of dipeptide and dipeptide derivative sweeteners |
| EP1620458B1 (de) * | 2003-05-06 | 2012-03-21 | NutraSweet Property Holdings, Inc. | SYNTHESE VON N-[N-(3,3-DIMETHYLBUTYL)-L-alpha-ASPARTYL] - L-PHENYLALANIN-1-METHYLESTER UNTER VERWENDUNG VON 3,3-DIMETHYLBUTYRALDEHYDDIMETHYLACETAL ALS VORLÄUFER |
| US7523774B2 (en) * | 2005-01-19 | 2009-04-28 | The Goodyear Tire & Rubber Company | Pneumatic tire with high turnup, locked bead construction |
| CN109467586B (zh) * | 2018-12-15 | 2021-06-22 | 济南诚汇双达化工有限公司 | 一种纽甜的精制方法 |
| CN110467648B (zh) * | 2019-07-24 | 2021-12-21 | 江苏理工学院 | 一种去除纽甜异味的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946988A (en) * | 1988-07-14 | 1990-08-07 | The Nutrasweet Company | Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester hydrochloride by use of isolated N-formyl L-aspartic anhydride |
| JP2970107B2 (ja) | 1991-05-23 | 1999-11-02 | 味の素株式会社 | α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造方法 |
| FR2697844B1 (fr) | 1992-11-12 | 1995-01-27 | Claude Nofre | Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation. |
| FR2719590B1 (fr) * | 1994-05-09 | 1996-07-26 | Claude Nofre | Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant. |
| US5728862A (en) | 1997-01-29 | 1998-03-17 | The Nutrasweet Company | Method for preparing and purifying an N-alkylated aspartame derivative |
| NL1010063C2 (nl) * | 1998-09-10 | 2000-03-13 | Holland Sweetener Co | Werkwijze voor de bereiding van neotaam. |
-
2001
- 2001-05-18 DE DE60108739T patent/DE60108739T2/de not_active Expired - Lifetime
- 2001-05-18 EP EP01937548A patent/EP1280818B1/de not_active Expired - Lifetime
- 2001-05-18 ES ES01937548T patent/ES2233644T3/es not_active Expired - Lifetime
- 2001-05-18 AT AT03023604T patent/ATE310013T1/de not_active IP Right Cessation
- 2001-05-18 AT AT01937548T patent/ATE288445T1/de not_active IP Right Cessation
- 2001-05-18 AU AU2001263267A patent/AU2001263267A1/en not_active Abandoned
- 2001-05-18 DE DE60115106T patent/DE60115106T2/de not_active Expired - Lifetime
- 2001-05-18 US US09/859,438 patent/US6642406B2/en not_active Expired - Lifetime
- 2001-05-18 ES ES03023604T patent/ES2253626T3/es not_active Expired - Lifetime
- 2001-05-18 WO PCT/US2001/016146 patent/WO2001087927A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001263267A1 (en) | 2001-11-26 |
| ATE310013T1 (de) | 2005-12-15 |
| DE60115106T2 (de) | 2006-07-13 |
| DE60108739T2 (de) | 2005-06-23 |
| DE60108739D1 (de) | 2005-03-10 |
| EP1280818A2 (de) | 2003-02-05 |
| ES2233644T3 (es) | 2005-06-16 |
| DE60115106D1 (de) | 2005-12-22 |
| EP1280818B1 (de) | 2005-02-02 |
| WO2001087927A3 (en) | 2002-05-10 |
| US6642406B2 (en) | 2003-11-04 |
| ES2253626T3 (es) | 2006-06-01 |
| WO2001087927A2 (en) | 2001-11-22 |
| US20020019557A1 (en) | 2002-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |