ATE280573T1 - Kontinuierlicher prozess für die herstellung von mikrokapseln mit verzögerten freisetzung von wasserlöslichen peptiden - Google Patents
Kontinuierlicher prozess für die herstellung von mikrokapseln mit verzögerten freisetzung von wasserlöslichen peptidenInfo
- Publication number
- ATE280573T1 ATE280573T1 AT01201558T AT01201558T ATE280573T1 AT E280573 T1 ATE280573 T1 AT E280573T1 AT 01201558 T AT01201558 T AT 01201558T AT 01201558 T AT01201558 T AT 01201558T AT E280573 T1 ATE280573 T1 AT E280573T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- water soluble
- continuous process
- delayed release
- soluble peptides
- Prior art date
Links
- 238000010924 continuous production Methods 0.000 title 1
- 230000003111 delayed effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000003094 microcapsule Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ARP000102102A AR023940A1 (es) | 2000-05-03 | 2000-05-03 | Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE280573T1 true ATE280573T1 (de) | 2004-11-15 |
Family
ID=3460812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01201558T ATE280573T1 (de) | 2000-05-03 | 2001-05-01 | Kontinuierlicher prozess für die herstellung von mikrokapseln mit verzögerten freisetzung von wasserlöslichen peptiden |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6534094B2 (de) |
| EP (1) | EP1151748B1 (de) |
| AR (1) | AR023940A1 (de) |
| AT (1) | ATE280573T1 (de) |
| DE (1) | DE60106666T2 (de) |
| ES (1) | ES2230231T3 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003000156A1 (en) | 2001-06-22 | 2003-01-03 | Southern Biosystems, Inc. | Zero-order prolonged release coaxial implants |
| CN1194688C (zh) * | 2001-07-03 | 2005-03-30 | 山东绿叶制药股份有限公司 | 石杉碱甲及其衍生物或其盐的注射用缓释微球及其制备方法 |
| US6974592B2 (en) * | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
| ATE470436T1 (de) * | 2002-11-04 | 2010-06-15 | Ocean Nutrition Canada Ltd | Mikrokapseln mit mehrfachen hüllen und verfahren zu deren herstellung |
| ES2308228T3 (es) * | 2003-10-16 | 2008-12-01 | Basell Poliolefine Italia S.P.A. | Proceso para la produccion continua de emulsiones. |
| WO2005110369A2 (en) * | 2004-04-30 | 2005-11-24 | American Pharmaceutical Partners, Inc. | Sustained-release microspheres and methods of making and using same |
| US8034450B2 (en) * | 2005-01-21 | 2011-10-11 | Ocean Nutrition Canada Limited | Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof |
| US6969530B1 (en) | 2005-01-21 | 2005-11-29 | Ocean Nutrition Canada Ltd. | Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof |
| CA2596023A1 (en) * | 2005-01-27 | 2006-11-09 | Ocean Nutrition Canada Ltd. | Fatty acid-benzenediol derivatives and methods of making and using thereof |
| US20080206316A1 (en) * | 2005-01-27 | 2008-08-28 | Colin Barrow | Chromium-Fatty Acid Compounds and Methods of Making and Using Thereof |
| AR048220A1 (es) * | 2005-01-28 | 2006-04-12 | Lkm S A Lab | Arreglo de dispositivos utilizables en la elaboracion de microcapsulas para la liberacion controlada de peptidos y procedimiento de elaboracion de dichas opcionalmente sustituido |
| US20090123556A1 (en) * | 2005-03-01 | 2009-05-14 | Sun Pharmaceutical Industries Limited | Sustained release pharmaceutical compositions |
| US20090104274A1 (en) * | 2005-03-01 | 2009-04-23 | Ajay Khopade | Process of making microspheres |
| KR100622996B1 (ko) | 2005-03-03 | 2006-09-14 | 한국과학기술원 | 약물이 봉입된 비다공성 고분자 미립 담체 및 이의 제조방법 |
| US9968120B2 (en) * | 2006-05-17 | 2018-05-15 | Dsm Nutritional Products Ag | Homogenized formulations containing microcapsules and methods of making and using thereof |
| US20070106271A1 (en) * | 2005-11-09 | 2007-05-10 | Searete Llc, A Limited Liability Corporation | Remote control of substance delivery system |
| AU2007238985B2 (en) * | 2006-04-07 | 2012-09-20 | Dsm Nutritional Products Ag | Emulsions and microcapsules with substances having low interfacial tension, methods of making and using thereof |
| ES2644753T3 (es) * | 2006-06-05 | 2017-11-30 | Dsm Nutritional Products Ag | Microcápsulas con cubiertas mejoradas |
| KR100853309B1 (ko) | 2006-11-01 | 2008-08-20 | 나재운 | 시프로플록사신이 담지된 폴리락타이드글리콜라이드공중합체의 서방출 및 생분해성 나노입자 및 그 제조방법 |
| KR100816065B1 (ko) * | 2006-11-27 | 2008-03-24 | 동국제약 주식회사 | 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐 |
| EP2124905B1 (de) | 2007-01-10 | 2016-09-07 | DSM Nutritional Products AG | Mikrokapseln enthaltend erbsenprotein |
| DK2148691T3 (en) | 2007-02-05 | 2015-08-17 | Apellis Pharmaceuticals Inc | Compstatinanaloger for use in the treatment of inflammatory states of the respiratory system |
| EP2139447A2 (de) * | 2007-03-20 | 2010-01-06 | Harold Brem | Gm-csf-kosmezeutikazusammensetzungen und verfahren zu ihrer verwendung |
| ATE516316T1 (de) * | 2008-02-13 | 2011-07-15 | Bayer Materialscience Ag | Verfahren zur herstellung von polycarbonaten |
| WO2010121307A1 (en) * | 2009-04-21 | 2010-10-28 | The University Of Queensland | Complex emulsions |
| US20110053776A1 (en) * | 2009-09-01 | 2011-03-03 | Bahr James T | Blends of micro-encapsulated pesticide formulations |
| KR20120098906A (ko) * | 2009-12-22 | 2012-09-05 | 다케다 야쿠힌 고교 가부시키가이샤 | 서방성 제제 |
| PH12012502548A1 (en) * | 2010-06-25 | 2013-02-11 | Takeda Pharmaceuticals Co | Sustained-release formulation |
| WO2013039096A1 (ja) * | 2011-09-13 | 2013-03-21 | 理研ビタミン株式会社 | 多芯型ゼラチンマイクロカプセルの製造方法 |
| KR20140107417A (ko) | 2011-12-14 | 2014-09-04 | 아브락시스 바이오사이언스, 엘엘씨 | 입자의 동결건조 또는 동결을 위한 중합체 부형제의 용도 |
| CN103191021A (zh) * | 2012-01-10 | 2013-07-10 | 山东绿叶制药有限公司 | 一种连续生产微球的设备及其应用 |
| ES2737975T3 (es) * | 2012-07-26 | 2020-01-17 | Koehler Se August Papierfabrik | Encapsulación de aceite aromático |
| EP2934562A1 (de) * | 2012-08-14 | 2015-10-28 | Wockhardt Limited | Mikropartikuläre pharmazeutische zusammensetzungen aus polypeptiden |
| JP6135292B2 (ja) * | 2013-05-10 | 2017-05-31 | ニプロ株式会社 | マイクロカプセル製剤の製造方法 |
| KR101686986B1 (ko) * | 2014-07-28 | 2016-12-16 | 에스케이케미칼주식회사 | 류프로라이드를 포함하는 속효성과 지속성을 동시에 갖는 약제학적 조성물 |
| KR20190101408A (ko) * | 2017-01-23 | 2019-08-30 | 세이비어 라이프텍 코퍼레이션 | 활성 성분의 미립자 제조 |
| CN107766606B (zh) * | 2017-09-01 | 2020-03-31 | 燕山大学 | 提升二次冷轧机组直喷系统乳化液工艺润滑性能的方法 |
| JP7581233B2 (ja) * | 2019-04-04 | 2024-11-12 | イントラ-セルラー・セラピーズ・インコーポレイテッド | 神経障害性疼痛の治療方法 |
| KR102171829B1 (ko) | 2019-11-15 | 2020-10-29 | 한국신발피혁연구원 | 웨트 슈트용 클로로프렌 발포체 조성물 |
| CN111000798B (zh) * | 2019-12-26 | 2021-11-23 | 四川恒博生物科技有限公司 | 一种采用原位凝胶技术的犬用非手术去势注射液 |
| US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
| WO2022103635A1 (en) | 2020-11-16 | 2022-05-19 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
| CN114662908B (zh) * | 2022-03-22 | 2025-01-14 | 鄂尔多斯市源盛光电有限责任公司 | 一种物流管理方法及相关设备 |
| CN115501143B (zh) * | 2022-10-21 | 2023-08-22 | 中科未来(无锡)生物技术研究院有限公司 | 一种含有雪莲培养物的抗敏舒缓组合物及其制备方法 |
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|---|---|---|---|---|
| US2800457A (en) | 1953-06-30 | 1957-07-23 | Ncr Co | Oil-containing microscopic capsules and method of making them |
| FR1362934A (fr) | 1962-07-11 | 1964-06-05 | Gevaert Photo Prod Nv | Méthode pour l'encapsulage d'eau et de composés en phase aqueuse |
| FR1362933A (fr) | 1962-07-11 | 1964-06-05 | Gevaert Photo Prod Nv | Procédé pour l'encapsulage d'eau et de composés en phase aqueuse |
| US3297033A (en) | 1963-10-31 | 1967-01-10 | American Cyanamid Co | Surgical sutures |
| BE744162A (fr) | 1969-01-16 | 1970-06-15 | Fuji Photo Film Co Ltd | Procede d'encapsulage |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3839297A (en) | 1971-11-22 | 1974-10-01 | Ethicon Inc | Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures |
| GB1413186A (en) | 1973-06-27 | 1975-11-12 | Toyo Jozo Kk | Process for encapsulation of medicaments |
| DE2438350C3 (de) | 1974-08-09 | 1979-06-13 | Hoechst Ag, 6000 Frankfurt | Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| US4010125A (en) | 1975-06-12 | 1977-03-01 | Schally Andrew Victor | [D-Trp6 ]-LH-RH and intermediates therefor |
| GB1524747A (en) | 1976-05-11 | 1978-09-13 | Ici Ltd | Polypeptide |
| US4234571A (en) | 1979-06-11 | 1980-11-18 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone |
| US4273920A (en) | 1979-09-12 | 1981-06-16 | Eli Lilly And Company | Polymerization process and product |
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| CH653553A5 (en) * | 1982-11-01 | 1986-01-15 | Sandoz Ag | Microencapsulation process |
| CH661206A5 (fr) | 1983-09-23 | 1987-07-15 | Debiopharm Sa | Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes. |
| JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| ATE61935T1 (de) | 1985-02-07 | 1991-04-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von mikrokapseln. |
| US5271945A (en) | 1988-07-05 | 1993-12-21 | Takeda Chemical Industries, Ltd. | Sustained release microcapsule for water soluble drug |
| ATE154241T1 (de) | 1991-10-01 | 1997-06-15 | Takeda Chemical Industries Ltd | Mikropartikeln-zusammenfassung zur verlängerten freigabe und herstellung derselbe |
| FR2693905B1 (fr) | 1992-07-27 | 1994-09-02 | Rhone Merieux | Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues. |
| ATE161716T1 (de) | 1992-08-07 | 1998-01-15 | Takeda Chemical Industries Ltd | Herstellung von mikrokapseln, die wasserlösliche arzneimittel enthalten |
| DE69429820T3 (de) * | 1993-11-19 | 2013-02-28 | Alkermes Controlled Therapeutics, Inc. | Herstellung biologisch abbaubarer, einen biologisch aktiven stoff enthaltender, mikropartikel |
| FR2718642B1 (fr) * | 1994-04-15 | 1996-07-12 | Pf Medicament | Microsphères biodégradables à libération contrôlée et leur procédé de préparation. |
| JP2909418B2 (ja) | 1995-09-18 | 1999-06-23 | 株式会社資生堂 | 薬物の遅延放出型マイクロスフイア |
| US5945126A (en) * | 1997-02-13 | 1999-08-31 | Oakwood Laboratories L.L.C. | Continuous microsphere process |
| DE19925184A1 (de) * | 1999-05-26 | 2000-11-30 | Schering Ag | Kontinuierliches Verfahren zur Herstellung von morphologisch einheitlichen Mikro- und Nanopartikeln mittels Mikromischer sowie nach diesem Verfahren hergestellte Partikel |
-
2000
- 2000-05-03 AR ARP000102102A patent/AR023940A1/es not_active Application Discontinuation
-
2001
- 2001-05-01 ES ES01201558T patent/ES2230231T3/es not_active Expired - Lifetime
- 2001-05-01 DE DE60106666T patent/DE60106666T2/de not_active Expired - Lifetime
- 2001-05-01 AT AT01201558T patent/ATE280573T1/de active
- 2001-05-01 EP EP01201558A patent/EP1151748B1/de not_active Expired - Lifetime
- 2001-05-03 US US09/848,623 patent/US6534094B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1151748A1 (de) | 2001-11-07 |
| US20020031553A1 (en) | 2002-03-14 |
| DE60106666T2 (de) | 2005-03-24 |
| AR023940A1 (es) | 2002-09-04 |
| ES2230231T3 (es) | 2005-05-01 |
| US6534094B2 (en) | 2003-03-18 |
| DE60106666D1 (de) | 2004-12-02 |
| EP1151748B1 (de) | 2004-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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