ATE280573T1 - Kontinuierlicher prozess für die herstellung von mikrokapseln mit verzögerten freisetzung von wasserlöslichen peptiden - Google Patents

Kontinuierlicher prozess für die herstellung von mikrokapseln mit verzögerten freisetzung von wasserlöslichen peptiden

Info

Publication number
ATE280573T1
ATE280573T1 AT01201558T AT01201558T ATE280573T1 AT E280573 T1 ATE280573 T1 AT E280573T1 AT 01201558 T AT01201558 T AT 01201558T AT 01201558 T AT01201558 T AT 01201558T AT E280573 T1 ATE280573 T1 AT E280573T1
Authority
AT
Austria
Prior art keywords
production
water soluble
continuous process
delayed release
soluble peptides
Prior art date
Application number
AT01201558T
Other languages
English (en)
Inventor
Nora Moyano
Jose Iturraspe
Jose Lucio Nunez
Original Assignee
Eriochem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eriochem Sa filed Critical Eriochem Sa
Application granted granted Critical
Publication of ATE280573T1 publication Critical patent/ATE280573T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]
    • Y10T428/2985Solid-walled microcapsule from synthetic polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01201558T 2000-05-03 2001-05-01 Kontinuierlicher prozess für die herstellung von mikrokapseln mit verzögerten freisetzung von wasserlöslichen peptiden ATE280573T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP000102102A AR023940A1 (es) 2000-05-03 2000-05-03 Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua

Publications (1)

Publication Number Publication Date
ATE280573T1 true ATE280573T1 (de) 2004-11-15

Family

ID=3460812

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01201558T ATE280573T1 (de) 2000-05-03 2001-05-01 Kontinuierlicher prozess für die herstellung von mikrokapseln mit verzögerten freisetzung von wasserlöslichen peptiden

Country Status (6)

Country Link
US (1) US6534094B2 (de)
EP (1) EP1151748B1 (de)
AR (1) AR023940A1 (de)
AT (1) ATE280573T1 (de)
DE (1) DE60106666T2 (de)
ES (1) ES2230231T3 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000156A1 (en) 2001-06-22 2003-01-03 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
CN1194688C (zh) * 2001-07-03 2005-03-30 山东绿叶制药股份有限公司 石杉碱甲及其衍生物或其盐的注射用缓释微球及其制备方法
US6974592B2 (en) * 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
ATE470436T1 (de) * 2002-11-04 2010-06-15 Ocean Nutrition Canada Ltd Mikrokapseln mit mehrfachen hüllen und verfahren zu deren herstellung
ES2308228T3 (es) * 2003-10-16 2008-12-01 Basell Poliolefine Italia S.P.A. Proceso para la produccion continua de emulsiones.
WO2005110369A2 (en) * 2004-04-30 2005-11-24 American Pharmaceutical Partners, Inc. Sustained-release microspheres and methods of making and using same
US8034450B2 (en) * 2005-01-21 2011-10-11 Ocean Nutrition Canada Limited Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
US6969530B1 (en) 2005-01-21 2005-11-29 Ocean Nutrition Canada Ltd. Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
CA2596023A1 (en) * 2005-01-27 2006-11-09 Ocean Nutrition Canada Ltd. Fatty acid-benzenediol derivatives and methods of making and using thereof
US20080206316A1 (en) * 2005-01-27 2008-08-28 Colin Barrow Chromium-Fatty Acid Compounds and Methods of Making and Using Thereof
AR048220A1 (es) * 2005-01-28 2006-04-12 Lkm S A Lab Arreglo de dispositivos utilizables en la elaboracion de microcapsulas para la liberacion controlada de peptidos y procedimiento de elaboracion de dichas opcionalmente sustituido
US20090123556A1 (en) * 2005-03-01 2009-05-14 Sun Pharmaceutical Industries Limited Sustained release pharmaceutical compositions
US20090104274A1 (en) * 2005-03-01 2009-04-23 Ajay Khopade Process of making microspheres
KR100622996B1 (ko) 2005-03-03 2006-09-14 한국과학기술원 약물이 봉입된 비다공성 고분자 미립 담체 및 이의 제조방법
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
US20070106271A1 (en) * 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Remote control of substance delivery system
AU2007238985B2 (en) * 2006-04-07 2012-09-20 Dsm Nutritional Products Ag Emulsions and microcapsules with substances having low interfacial tension, methods of making and using thereof
ES2644753T3 (es) * 2006-06-05 2017-11-30 Dsm Nutritional Products Ag Microcápsulas con cubiertas mejoradas
KR100853309B1 (ko) 2006-11-01 2008-08-20 나재운 시프로플록사신이 담지된 폴리락타이드글리콜라이드공중합체의 서방출 및 생분해성 나노입자 및 그 제조방법
KR100816065B1 (ko) * 2006-11-27 2008-03-24 동국제약 주식회사 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐
EP2124905B1 (de) 2007-01-10 2016-09-07 DSM Nutritional Products AG Mikrokapseln enthaltend erbsenprotein
DK2148691T3 (en) 2007-02-05 2015-08-17 Apellis Pharmaceuticals Inc Compstatinanaloger for use in the treatment of inflammatory states of the respiratory system
EP2139447A2 (de) * 2007-03-20 2010-01-06 Harold Brem Gm-csf-kosmezeutikazusammensetzungen und verfahren zu ihrer verwendung
ATE516316T1 (de) * 2008-02-13 2011-07-15 Bayer Materialscience Ag Verfahren zur herstellung von polycarbonaten
WO2010121307A1 (en) * 2009-04-21 2010-10-28 The University Of Queensland Complex emulsions
US20110053776A1 (en) * 2009-09-01 2011-03-03 Bahr James T Blends of micro-encapsulated pesticide formulations
KR20120098906A (ko) * 2009-12-22 2012-09-05 다케다 야쿠힌 고교 가부시키가이샤 서방성 제제
PH12012502548A1 (en) * 2010-06-25 2013-02-11 Takeda Pharmaceuticals Co Sustained-release formulation
WO2013039096A1 (ja) * 2011-09-13 2013-03-21 理研ビタミン株式会社 多芯型ゼラチンマイクロカプセルの製造方法
KR20140107417A (ko) 2011-12-14 2014-09-04 아브락시스 바이오사이언스, 엘엘씨 입자의 동결건조 또는 동결을 위한 중합체 부형제의 용도
CN103191021A (zh) * 2012-01-10 2013-07-10 山东绿叶制药有限公司 一种连续生产微球的设备及其应用
ES2737975T3 (es) * 2012-07-26 2020-01-17 Koehler Se August Papierfabrik Encapsulación de aceite aromático
EP2934562A1 (de) * 2012-08-14 2015-10-28 Wockhardt Limited Mikropartikuläre pharmazeutische zusammensetzungen aus polypeptiden
JP6135292B2 (ja) * 2013-05-10 2017-05-31 ニプロ株式会社 マイクロカプセル製剤の製造方法
KR101686986B1 (ko) * 2014-07-28 2016-12-16 에스케이케미칼주식회사 류프로라이드를 포함하는 속효성과 지속성을 동시에 갖는 약제학적 조성물
KR20190101408A (ko) * 2017-01-23 2019-08-30 세이비어 라이프텍 코퍼레이션 활성 성분의 미립자 제조
CN107766606B (zh) * 2017-09-01 2020-03-31 燕山大学 提升二次冷轧机组直喷系统乳化液工艺润滑性能的方法
JP7581233B2 (ja) * 2019-04-04 2024-11-12 イントラ-セルラー・セラピーズ・インコーポレイテッド 神経障害性疼痛の治療方法
KR102171829B1 (ko) 2019-11-15 2020-10-29 한국신발피혁연구원 웨트 슈트용 클로로프렌 발포체 조성물
CN111000798B (zh) * 2019-12-26 2021-11-23 四川恒博生物科技有限公司 一种采用原位凝胶技术的犬用非手术去势注射液
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
WO2022103635A1 (en) 2020-11-16 2022-05-19 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
CN114662908B (zh) * 2022-03-22 2025-01-14 鄂尔多斯市源盛光电有限责任公司 一种物流管理方法及相关设备
CN115501143B (zh) * 2022-10-21 2023-08-22 中科未来(无锡)生物技术研究院有限公司 一种含有雪莲培养物的抗敏舒缓组合物及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800457A (en) 1953-06-30 1957-07-23 Ncr Co Oil-containing microscopic capsules and method of making them
FR1362934A (fr) 1962-07-11 1964-06-05 Gevaert Photo Prod Nv Méthode pour l'encapsulage d'eau et de composés en phase aqueuse
FR1362933A (fr) 1962-07-11 1964-06-05 Gevaert Photo Prod Nv Procédé pour l'encapsulage d'eau et de composés en phase aqueuse
US3297033A (en) 1963-10-31 1967-01-10 American Cyanamid Co Surgical sutures
BE744162A (fr) 1969-01-16 1970-06-15 Fuji Photo Film Co Ltd Procede d'encapsulage
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3839297A (en) 1971-11-22 1974-10-01 Ethicon Inc Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures
GB1413186A (en) 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
DE2438350C3 (de) 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
US4010125A (en) 1975-06-12 1977-03-01 Schally Andrew Victor [D-Trp6 ]-LH-RH and intermediates therefor
GB1524747A (en) 1976-05-11 1978-09-13 Ici Ltd Polypeptide
US4234571A (en) 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
US4273920A (en) 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
US4675189A (en) 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
CH653553A5 (en) * 1982-11-01 1986-01-15 Sandoz Ag Microencapsulation process
CH661206A5 (fr) 1983-09-23 1987-07-15 Debiopharm Sa Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
JPS60100516A (ja) 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
ATE61935T1 (de) 1985-02-07 1991-04-15 Takeda Chemical Industries Ltd Verfahren zur herstellung von mikrokapseln.
US5271945A (en) 1988-07-05 1993-12-21 Takeda Chemical Industries, Ltd. Sustained release microcapsule for water soluble drug
ATE154241T1 (de) 1991-10-01 1997-06-15 Takeda Chemical Industries Ltd Mikropartikeln-zusammenfassung zur verlängerten freigabe und herstellung derselbe
FR2693905B1 (fr) 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
ATE161716T1 (de) 1992-08-07 1998-01-15 Takeda Chemical Industries Ltd Herstellung von mikrokapseln, die wasserlösliche arzneimittel enthalten
DE69429820T3 (de) * 1993-11-19 2013-02-28 Alkermes Controlled Therapeutics, Inc. Herstellung biologisch abbaubarer, einen biologisch aktiven stoff enthaltender, mikropartikel
FR2718642B1 (fr) * 1994-04-15 1996-07-12 Pf Medicament Microsphères biodégradables à libération contrôlée et leur procédé de préparation.
JP2909418B2 (ja) 1995-09-18 1999-06-23 株式会社資生堂 薬物の遅延放出型マイクロスフイア
US5945126A (en) * 1997-02-13 1999-08-31 Oakwood Laboratories L.L.C. Continuous microsphere process
DE19925184A1 (de) * 1999-05-26 2000-11-30 Schering Ag Kontinuierliches Verfahren zur Herstellung von morphologisch einheitlichen Mikro- und Nanopartikeln mittels Mikromischer sowie nach diesem Verfahren hergestellte Partikel

Also Published As

Publication number Publication date
EP1151748A1 (de) 2001-11-07
US20020031553A1 (en) 2002-03-14
DE60106666T2 (de) 2005-03-24
AR023940A1 (es) 2002-09-04
ES2230231T3 (es) 2005-05-01
US6534094B2 (en) 2003-03-18
DE60106666D1 (de) 2004-12-02
EP1151748B1 (de) 2004-10-27

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