ATE277024T1 - Verfahren zur herstellung eines 4- thiazolylmethylderivates - Google Patents

Verfahren zur herstellung eines 4- thiazolylmethylderivates

Info

Publication number
ATE277024T1
ATE277024T1 AT99906538T AT99906538T ATE277024T1 AT E277024 T1 ATE277024 T1 AT E277024T1 AT 99906538 T AT99906538 T AT 99906538T AT 99906538 T AT99906538 T AT 99906538T AT E277024 T1 ATE277024 T1 AT E277024T1
Authority
AT
Austria
Prior art keywords
thiazolylmethyl
derivative
producing
halogen
production
Prior art date
Application number
AT99906538T
Other languages
English (en)
Inventor
Masaaki Uenaka
Masahiko Nagai
Naotake Kobayashi
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE277024T1 publication Critical patent/ATE277024T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT99906538T 1998-03-02 1999-03-01 Verfahren zur herstellung eines 4- thiazolylmethylderivates ATE277024T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4925998 1998-03-02
PCT/JP1999/000975 WO1999045000A1 (fr) 1998-03-02 1999-03-01 Procede de production d'un derive de 4-thiazolylmethyle

Publications (1)

Publication Number Publication Date
ATE277024T1 true ATE277024T1 (de) 2004-10-15

Family

ID=12825843

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99906538T ATE277024T1 (de) 1998-03-02 1999-03-01 Verfahren zur herstellung eines 4- thiazolylmethylderivates

Country Status (9)

Country Link
US (1) US6506903B1 (de)
EP (1) EP1069118B1 (de)
JP (1) JP3811885B2 (de)
AT (1) ATE277024T1 (de)
AU (1) AU2642399A (de)
DE (1) DE69920423T2 (de)
ES (1) ES2229680T3 (de)
TW (1) TW530052B (de)
WO (1) WO1999045000A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60014939T2 (de) * 1999-08-30 2006-03-09 Shionogi & Co., Ltd. Verfahren für die herstellung von oxo-oxazoline oder alloaminosäuren
KR20050105290A (ko) * 2000-08-31 2005-11-03 시오노기세이야쿠가부시키가이샤 파킨슨씨병 치료제
CA2707768C (en) 2007-12-19 2016-01-05 Avon Products, Inc. Topical compositions comprising non-proteogenic amino acids and methods of treating skin
JP5981719B2 (ja) * 2009-06-08 2016-08-31 株式会社カネカ 光学活性チアゾリルアラニン誘導体およびその塩の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE166051T1 (de) 1987-08-01 1998-05-15 Takeda Chemical Industries Ltd Zwischenprodukte, ihre herstellung und verwendung zur herstellung alpha-ungesättigter amine
US5275950A (en) 1990-05-11 1994-01-04 Abbott Laboratories Process for the preparation of a renin inhibiting compound
US5492916A (en) * 1993-12-23 1996-02-20 Merck & Co., Inc. Di- and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
US5459274A (en) 1994-05-13 1995-10-17 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines
AU713133B2 (en) * 1996-08-28 1999-11-25 Shionogi & Co., Ltd. Novel peptide derivatives having thiazolyl-alanine residue

Also Published As

Publication number Publication date
DE69920423D1 (de) 2004-10-28
US6506903B1 (en) 2003-01-14
WO1999045000A1 (fr) 1999-09-10
JP3811885B2 (ja) 2006-08-23
ES2229680T3 (es) 2005-04-16
EP1069118A1 (de) 2001-01-17
EP1069118A4 (de) 2002-06-05
DE69920423T2 (de) 2006-02-23
EP1069118B1 (de) 2004-09-22
AU2642399A (en) 1999-09-20
TW530052B (en) 2003-05-01

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Legal Events

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