ATE275641T1 - Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips - Google Patents

Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips

Info

Publication number
ATE275641T1
ATE275641T1 AT01907873T AT01907873T ATE275641T1 AT E275641 T1 ATE275641 T1 AT E275641T1 AT 01907873 T AT01907873 T AT 01907873T AT 01907873 T AT01907873 T AT 01907873T AT E275641 T1 ATE275641 T1 AT E275641T1
Authority
AT
Austria
Prior art keywords
fluorescence
analysis
target molecules
biological target
fluorescence marker
Prior art date
Application number
AT01907873T
Other languages
English (en)
Inventor
Marc Cuzin
Philippe Peltie
Marc Fontecave
Jean-Luc Decout
Cecile Dueymes
Original Assignee
Commissariat Energie Atomique
Univ Joseph Fourier De Grenobl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique, Univ Joseph Fourier De Grenobl filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE275641T1 publication Critical patent/ATE275641T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00527Sheets
    • B01J2219/00529DNA chips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572Chemical means
    • B01J2219/00576Chemical means fluorophore
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608DNA chips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00693Means for quality control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00702Processes involving means for analysing and characterising the products
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
AT01907873T 2000-02-23 2001-02-22 Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips ATE275641T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0002236A FR2805348B1 (fr) 2000-02-23 2000-02-23 Analyse de cibles biologiques utilisant une biopuce comportant un marqueur fluorescent
PCT/FR2001/000516 WO2001063282A2 (fr) 2000-02-23 2001-02-22 Analyse de cibles biologiques utilisant une biopuce comportant un marqueur fluorescent

Publications (1)

Publication Number Publication Date
ATE275641T1 true ATE275641T1 (de) 2004-09-15

Family

ID=8847290

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01907873T ATE275641T1 (de) 2000-02-23 2001-02-22 Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips
AT03104367T ATE541050T1 (de) 2000-02-23 2001-02-22 Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03104367T ATE541050T1 (de) 2000-02-23 2001-02-22 Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips

Country Status (9)

Country Link
US (1) US6861515B2 (de)
EP (2) EP1413630B1 (de)
JP (1) JP4729226B2 (de)
AT (2) ATE275641T1 (de)
AU (1) AU2001235742A1 (de)
CA (1) CA2399258A1 (de)
DE (1) DE60105399T2 (de)
FR (1) FR2805348B1 (de)
WO (1) WO2001063282A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1715063E (pt) * 2000-03-29 2011-04-28 Lgc Ltd Farol de hibridização e método para a detecção e discriminação rápida de sequência
CA2441279A1 (en) * 2001-03-16 2002-09-26 Qtl Biosystems, Llc Fluorescent polymer superquenching-based bioassays
FR2827304B1 (fr) * 2001-07-16 2004-05-21 Commissariat Energie Atomique Procede et support d'analyse biologique utilisant des oligonucleotides comportant un marqueur activable enzymatiquement
DE10155055A1 (de) * 2001-11-09 2003-05-28 Friz Biochem Gmbh Fluoreszenz-Quenchen zur Detektion von Nukleinsäure-Oligomer-Hybridisierungsereignissen bei hohen Salz-Konzentrationen
CN1424405A (zh) * 2001-12-14 2003-06-18 宋克 基因芯片分子探针及相关技术

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US5538848A (en) * 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US5578832A (en) * 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US5843655A (en) * 1995-09-18 1998-12-01 Affymetrix, Inc. Methods for testing oligonucleotide arrays
US5861247A (en) * 1996-01-26 1999-01-19 University Of Chicago Rapid method to detect duplex formation in sequencing by hybridization methods
US5646411A (en) * 1996-02-01 1997-07-08 Molecular Dynamics, Inc. Fluorescence imaging system compatible with macro and micro scanning objectives
SE522077C2 (sv) * 1997-09-05 2004-01-13 Lightup Technologies Ab Förfarande att välja sekvens hos sond för nukleinsyrahybridisering
CN1268979A (zh) * 1997-07-22 2000-10-04 拉普吉恩公司 阵列单元的多功能性及其用途
WO1999060158A1 (fr) * 1998-05-19 1999-11-25 Laboratory Of Molecular Biophotonics Phase solide utilisee pour detecter de l'acide nucleique et procede de detection d'acide nucleique
WO2001038585A2 (en) 1999-11-24 2001-05-31 The Regents Of The University Of California Polymer arrays and methods of using labeled probe molecules to identify and quantify target molecule expression

Also Published As

Publication number Publication date
WO2001063282A2 (fr) 2001-08-30
EP1413630B1 (de) 2012-01-11
EP1413630A1 (de) 2004-04-28
CA2399258A1 (fr) 2001-08-30
ATE541050T1 (de) 2012-01-15
WO2001063282A3 (fr) 2002-04-04
FR2805348A1 (fr) 2001-08-24
FR2805348B1 (fr) 2002-07-12
JP4729226B2 (ja) 2011-07-20
EP1266030B1 (de) 2004-09-08
US6861515B2 (en) 2005-03-01
EP1266030A2 (de) 2002-12-18
DE60105399D1 (de) 2004-10-14
AU2001235742A1 (en) 2001-09-03
DE60105399T2 (de) 2005-09-15
US20030165914A1 (en) 2003-09-04
JP2003529751A (ja) 2003-10-07

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