ATE267820T1 - Prozess zur herstellung von paclitaxel - Google Patents
Prozess zur herstellung von paclitaxelInfo
- Publication number
- ATE267820T1 ATE267820T1 AT01985349T AT01985349T ATE267820T1 AT E267820 T1 ATE267820 T1 AT E267820T1 AT 01985349 T AT01985349 T AT 01985349T AT 01985349 T AT01985349 T AT 01985349T AT E267820 T1 ATE267820 T1 AT E267820T1
- Authority
- AT
- Austria
- Prior art keywords
- making paclitaxel
- paclitaxel
- making
- preparation
- deacetylbaccatine iii
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI002654A IT1319682B1 (it) | 2000-12-06 | 2000-12-06 | Procedimento di sintesi del paclitaxel. |
| PCT/EP2001/014084 WO2002046177A1 (en) | 2000-12-06 | 2001-12-03 | A process for the preparation of paclitaxel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE267820T1 true ATE267820T1 (de) | 2004-06-15 |
Family
ID=11446197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01985349T ATE267820T1 (de) | 2000-12-06 | 2001-12-03 | Prozess zur herstellung von paclitaxel |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6768012B2 (de) |
| EP (1) | EP1339703B1 (de) |
| JP (1) | JP2004515497A (de) |
| KR (1) | KR100846891B1 (de) |
| CN (1) | CN1286828C (de) |
| AT (1) | ATE267820T1 (de) |
| AU (2) | AU3453502A (de) |
| CA (1) | CA2430814C (de) |
| CZ (1) | CZ300024B6 (de) |
| DE (1) | DE60103560T2 (de) |
| DK (1) | DK1339703T3 (de) |
| ES (1) | ES2221656T3 (de) |
| HK (1) | HK1063052A1 (de) |
| HU (1) | HU229373B1 (de) |
| IL (2) | IL156331A0 (de) |
| IT (1) | IT1319682B1 (de) |
| NO (1) | NO328505B1 (de) |
| PL (1) | PL195121B1 (de) |
| PT (1) | PT1339703E (de) |
| RU (1) | RU2276147C2 (de) |
| SK (1) | SK286616B6 (de) |
| TR (1) | TR200401435T4 (de) |
| WO (1) | WO2002046177A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1319682B1 (it) * | 2000-12-06 | 2003-10-23 | Indena Spa | Procedimento di sintesi del paclitaxel. |
| ITMI20012185A1 (it) * | 2001-10-19 | 2003-04-19 | Indena Spa | Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato |
| WO2004068930A2 (en) * | 2003-02-04 | 2004-08-19 | Natural Pharmaceuticals Inc. | Method and composition for preparing a compound using a benzolating agent essentially free of ring chlorination |
| CN1303077C (zh) * | 2004-01-16 | 2007-03-07 | 桂林晖昂生化药业有限责任公司 | 合成紫杉烷的制备工艺 |
| ITMI20050614A1 (it) * | 2005-04-12 | 2006-10-13 | Indena Spa | Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii |
| DK1854799T3 (da) * | 2006-05-12 | 2011-07-18 | Indena Spa | Fremgangsmåde til fremstilling af et taxanderivat |
| CN102887876B (zh) * | 2012-02-15 | 2015-11-25 | 浙江大学宁波理工学院 | 一种改进的多西紫杉醇的半合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7288665B1 (en) * | 1997-08-18 | 2007-10-30 | Florida State University | Process for selective derivatization of taxanes |
| US5917062A (en) * | 1997-11-21 | 1999-06-29 | Indena S.P.A | Intermediates and methods useful in the semisynthesis of paclitaxel and analogs |
| US6020507A (en) * | 1998-03-02 | 2000-02-01 | Bristol-Myers Squibb Company | Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile |
| IT1319682B1 (it) * | 2000-12-06 | 2003-10-23 | Indena Spa | Procedimento di sintesi del paclitaxel. |
-
2000
- 2000-12-06 IT IT2000MI002654A patent/IT1319682B1/it active
-
2001
- 2001-12-03 KR KR1020037007262A patent/KR100846891B1/ko active IP Right Grant
- 2001-12-03 WO PCT/EP2001/014084 patent/WO2002046177A1/en active IP Right Grant
- 2001-12-03 DE DE60103560T patent/DE60103560T2/de not_active Expired - Lifetime
- 2001-12-03 RU RU2003116901/04A patent/RU2276147C2/ru not_active IP Right Cessation
- 2001-12-03 TR TR2004/01435T patent/TR200401435T4/xx unknown
- 2001-12-03 JP JP2002547916A patent/JP2004515497A/ja active Pending
- 2001-12-03 EP EP01985349A patent/EP1339703B1/de not_active Expired - Lifetime
- 2001-12-03 CN CNB018200745A patent/CN1286828C/zh not_active Expired - Fee Related
- 2001-12-03 CZ CZ20031534A patent/CZ300024B6/cs not_active IP Right Cessation
- 2001-12-03 PT PT01985349T patent/PT1339703E/pt unknown
- 2001-12-03 SK SK697-2003A patent/SK286616B6/sk not_active IP Right Cessation
- 2001-12-03 AU AU3453502A patent/AU3453502A/xx active Pending
- 2001-12-03 AU AU2002234535A patent/AU2002234535B2/en not_active Ceased
- 2001-12-03 ES ES01985349T patent/ES2221656T3/es not_active Expired - Lifetime
- 2001-12-03 AT AT01985349T patent/ATE267820T1/de active
- 2001-12-03 CA CA002430814A patent/CA2430814C/en not_active Expired - Lifetime
- 2001-12-03 PL PL01366120A patent/PL195121B1/pl unknown
- 2001-12-03 HU HU0500615A patent/HU229373B1/hu not_active IP Right Cessation
- 2001-12-03 DK DK01985349T patent/DK1339703T3/da active
- 2001-12-03 US US10/433,601 patent/US6768012B2/en not_active Expired - Lifetime
- 2001-12-03 IL IL15633101A patent/IL156331A0/xx active IP Right Grant
-
2003
- 2003-06-05 IL IL156331A patent/IL156331A/en unknown
- 2003-06-05 NO NO20032558A patent/NO328505B1/no not_active IP Right Cessation
-
2004
- 2004-08-06 HK HK04105846A patent/HK1063052A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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