ATE266017T1 - Radicicolderivate - Google Patents
RadicicolderivateInfo
- Publication number
- ATE266017T1 ATE266017T1 AT97909629T AT97909629T ATE266017T1 AT E266017 T1 ATE266017 T1 AT E266017T1 AT 97909629 T AT97909629 T AT 97909629T AT 97909629 T AT97909629 T AT 97909629T AT E266017 T1 ATE266017 T1 AT E266017T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- unsubstituted
- lower alkyl
- alkanoyl
- tert
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28443996 | 1996-10-25 | ||
| JP357897 | 1997-01-13 | ||
| PCT/JP1997/003874 WO1998018780A1 (fr) | 1996-10-25 | 1997-10-24 | Derives de radicicol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE266017T1 true ATE266017T1 (de) | 2004-05-15 |
Family
ID=26337204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97909629T ATE266017T1 (de) | 1996-10-25 | 1997-10-24 | Radicicolderivate |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US6316491B1 (de) |
| EP (1) | EP0889042B1 (de) |
| KR (1) | KR19990076764A (de) |
| CN (1) | CN1211244A (de) |
| AT (1) | ATE266017T1 (de) |
| AU (1) | AU727722B2 (de) |
| CA (1) | CA2241624A1 (de) |
| DE (1) | DE69728974T2 (de) |
| ES (1) | ES2216130T3 (de) |
| NO (1) | NO982960L (de) |
| NZ (1) | NZ331062A (de) |
| WO (1) | WO1998018780A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6838810B1 (en) * | 1997-03-21 | 2005-01-04 | Chunghwa Picture Tubes, Ltd. | Flat-panel display mounting system for portable computer |
| CA2287387C (en) | 1997-05-14 | 2010-02-16 | Sloan-Kettering Institute For Cancer Research | Methods and compositions for destruction of selected proteins |
| AU3534499A (en) * | 1998-04-24 | 1999-11-16 | Kyowa Hakko Kogyo Co. Ltd. | Radicicol derivatives |
| US6635671B1 (en) | 1998-12-24 | 2003-10-21 | Novation Pharmaceuticals Inc. | Compounds which affect mRNA stability and uses therefor |
| WO2000045805A2 (en) * | 1999-02-08 | 2000-08-10 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Methods of inhibiting the hgf-met-upa-plasmin network with geldanamycin derivates |
| WO2000061578A1 (en) | 1999-04-09 | 2000-10-19 | Sloan-Kettering Institute For Cancer Research | Methods and compositions for degradation and/or inhibition of her-family tyrosine kinases |
| US7238682B1 (en) | 1999-04-09 | 2007-07-03 | Sloan-Kettering Institute For Cancer Research | Methods and compositions for degradation and/or inhibition of HER-family tyrosine kinases |
| US6979574B1 (en) * | 1999-08-06 | 2005-12-27 | Institut Fuer Diagnostik Forshung Gmbh | Process for detecting binding reactions with use of the measurement of the relaxation of the double refraction of magnetic particles |
| AU2001292548B2 (en) * | 2000-07-28 | 2005-06-16 | Sloan-Kettering Institute For Cancer Research | Methods for treating cell proliferative disorders and viral infections |
| DE60120427D1 (de) | 2000-08-25 | 2006-07-20 | Sloan Kettering Inst Cancer | Radicicol und monocillin und ihre analogen und ihre anwendungen |
| US7825094B2 (en) * | 2001-05-23 | 2010-11-02 | Sloan-Kettering Institute For Cancer Research | Method of treatment for cancers associated with elevated HER 2 levels |
| CN100560131C (zh) | 2001-10-22 | 2009-11-18 | 斯克里普斯研究学院 | 抗体靶向化合物 |
| CN1606566A (zh) * | 2001-10-22 | 2005-04-13 | 斯克里普斯研究学院 | 整联蛋白靶向化合物 |
| KR101129215B1 (ko) | 2003-06-27 | 2012-04-13 | 교와 핫꼬 기린 가부시키가이샤 | Ｈｓｐ90 패밀리 단백질 저해제 |
| WO2005061481A1 (en) * | 2003-12-19 | 2005-07-07 | Sloan-Kettering Institute For Cancer Research | Novel ma crocycles and uses thereof |
| CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
| EP1945262A2 (de) * | 2005-10-20 | 2008-07-23 | The Scripps Research Institute | Fc-etikettierung für immunostaining und immunotargeting |
| GB0526615D0 (en) * | 2005-12-30 | 2006-02-08 | Novartis Ag | Organic compounds |
| CN101588799B (zh) * | 2006-08-11 | 2013-09-11 | 斯特拉斯堡大学 | 用作激酶抑制剂和hsp90抑制剂的大环化合物 |
| MX2010007755A (es) | 2008-01-15 | 2010-12-21 | Univ Strasbourg | Sintesis de lactonas de acido resorcilico utiles como agentes terapeuticos. |
| US20110190237A1 (en) * | 2008-01-15 | 2011-08-04 | Nexgenix Pharmaceuticals | Macrocyclic Prodrug Compounds Useful as Therapeutics |
| EP2254880B8 (de) | 2008-02-21 | 2016-09-21 | OncoSynergy, Inc. | Als Therapeutika geeignete makrocyclische Prodrugverbindungen |
| LT5623B (lt) | 2008-04-30 | 2010-01-25 | Biotechnologijos Institutas, , | 5-aril-4-(5-pakeistieji 2,4-dihidroksifenil)-1,2,3-tiadiazolai kaip hsp90 šaperono slopikliai ir tarpiniai junginiai jiems gauti |
| JP2012517447A (ja) | 2009-02-10 | 2012-08-02 | ザ スクリプス リサーチ インスティチュート | 化学的にプログラムされたワクチン接種法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR920000763A (ko) | 1990-06-06 | 1992-01-29 | 가와무라 요시부미 | 라디시콜 유도체, 그 제조방법 및 그의 항종양 활성 |
| US5650430A (en) | 1990-06-06 | 1997-07-22 | Sankyo Company, Limited | Radicicol derivatives, their preparation and their anti-tumor activity |
| JP3055967B2 (ja) | 1990-06-06 | 2000-06-26 | 三共株式会社 | ラディシコール誘導体 |
| JPH06279279A (ja) | 1993-03-26 | 1994-10-04 | Tsumura & Co | 血管新生阻害剤 |
| JPH06298764A (ja) | 1993-04-15 | 1994-10-25 | Kyowa Hakko Kogyo Co Ltd | 免疫抑制剤 |
| JPH0840893A (ja) * | 1993-08-31 | 1996-02-13 | Takeda Chem Ind Ltd | インターロイキン−１産生抑制剤 |
| US5731343A (en) * | 1995-02-24 | 1998-03-24 | The Scripps Research Institute | Method of use of radicicol for treatment of immunopathological disorders |
| KR19990008051A (ko) * | 1995-04-26 | 1999-01-25 | 히라타다다시 | 라디시콜 유도체 |
| JPH09202781A (ja) | 1996-01-25 | 1997-08-05 | Sankyo Co Ltd | ラディシコール誘導体 |
-
1997
- 1997-10-24 DE DE69728974T patent/DE69728974T2/de not_active Expired - Fee Related
- 1997-10-24 NZ NZ331062A patent/NZ331062A/xx unknown
- 1997-10-24 CA CA002241624A patent/CA2241624A1/en not_active Abandoned
- 1997-10-24 AU AU47239/97A patent/AU727722B2/en not_active Ceased
- 1997-10-24 EP EP97909629A patent/EP0889042B1/de not_active Expired - Lifetime
- 1997-10-24 AT AT97909629T patent/ATE266017T1/de not_active IP Right Cessation
- 1997-10-24 US US09/091,752 patent/US6316491B1/en not_active Expired - Fee Related
- 1997-10-24 CN CN97192375A patent/CN1211244A/zh active Pending
- 1997-10-24 KR KR1019980704887A patent/KR19990076764A/ko not_active Application Discontinuation
- 1997-10-24 WO PCT/JP1997/003874 patent/WO1998018780A1/ja not_active Application Discontinuation
- 1997-10-24 ES ES97909629T patent/ES2216130T3/es not_active Expired - Lifetime
-
1998
- 1998-06-25 NO NO982960A patent/NO982960L/no unknown
-
2000
- 2000-02-25 US US09/513,472 patent/US6239168B1/en not_active Expired - Fee Related
-
2001
- 2001-02-26 US US09/791,602 patent/US6635662B2/en not_active Expired - Fee Related
-
2003
- 2003-07-30 US US10/629,655 patent/US20040053990A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU4723997A (en) | 1998-05-22 |
| KR19990076764A (ko) | 1999-10-15 |
| EP0889042A1 (de) | 1999-01-07 |
| DE69728974T2 (de) | 2005-03-31 |
| EP0889042B1 (de) | 2004-05-06 |
| CN1211244A (zh) | 1999-03-17 |
| EP0889042A4 (de) | 1999-10-06 |
| US6635662B2 (en) | 2003-10-21 |
| ES2216130T3 (es) | 2004-10-16 |
| AU727722B2 (en) | 2000-12-21 |
| US6316491B1 (en) | 2001-11-13 |
| US20040053990A1 (en) | 2004-03-18 |
| CA2241624A1 (en) | 1998-05-07 |
| NO982960D0 (no) | 1998-06-25 |
| NO982960L (no) | 1998-08-25 |
| WO1998018780A1 (fr) | 1998-05-07 |
| DE69728974D1 (de) | 2004-06-09 |
| US20010027208A1 (en) | 2001-10-04 |
| NZ331062A (en) | 2000-05-26 |
| US6239168B1 (en) | 2001-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |