ATE265204T1 - Micropartikeln zur verwendung in nadellosen injektion - Google Patents
Micropartikeln zur verwendung in nadellosen injektionInfo
- Publication number
- ATE265204T1 ATE265204T1 AT99943130T AT99943130T ATE265204T1 AT E265204 T1 ATE265204 T1 AT E265204T1 AT 99943130 T AT99943130 T AT 99943130T AT 99943130 T AT99943130 T AT 99943130T AT E265204 T1 ATE265204 T1 AT E265204T1
- Authority
- AT
- Austria
- Prior art keywords
- microparticles
- needleless injection
- therapeutic agent
- agent
- spray
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Glanulating (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Disintegrating Or Milling (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9819272.7A GB9819272D0 (en) | 1998-09-03 | 1998-09-03 | Microparticles |
PCT/GB1999/002930 WO2000013668A1 (en) | 1998-09-03 | 1999-09-03 | Microparticles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE265204T1 true ATE265204T1 (de) | 2004-05-15 |
Family
ID=10838317
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99943130T ATE265204T1 (de) | 1998-09-03 | 1999-09-03 | Micropartikeln zur verwendung in nadellosen injektion |
AT04075082T ATE386507T1 (de) | 1998-09-03 | 1999-09-03 | Mikropartikel |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04075082T ATE386507T1 (de) | 1998-09-03 | 1999-09-03 | Mikropartikel |
Country Status (15)
Country | Link |
---|---|
US (3) | US20020197325A1 (de) |
EP (2) | EP1107737B1 (de) |
JP (2) | JP2002524411A (de) |
CN (1) | CN1315854A (de) |
AT (2) | ATE265204T1 (de) |
AU (1) | AU5640799A (de) |
BR (1) | BR9913456A (de) |
CA (1) | CA2342206C (de) |
DE (2) | DE69938201T2 (de) |
DK (1) | DK1107737T3 (de) |
ES (2) | ES2301929T3 (de) |
GB (1) | GB9819272D0 (de) |
IL (1) | IL141323A0 (de) |
MX (1) | MXPA01002323A (de) |
WO (1) | WO2000013668A1 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2364198A1 (en) * | 1999-03-08 | 2000-09-14 | Powderject Research Limited | Delivery of microparticle formulations using needleless syringe device for sustained-release of bioactive compounds |
US8771740B2 (en) * | 1999-12-20 | 2014-07-08 | Nicholas J. Kerkhof | Process for producing nanoparticles by spray drying |
DE10045521A1 (de) | 2000-03-31 | 2001-10-04 | Roche Diagnostics Gmbh | Nukleinsäureamplifikationen |
JP2004521111A (ja) * | 2001-01-25 | 2004-07-15 | ユーロ−セルティーク,エス.エイ. | 局所麻酔薬および使用法 |
WO2002100380A1 (en) * | 2001-06-08 | 2002-12-19 | Powderject Vaccines, Inc. | Production of hard, dense particles |
EP1446104B2 (de) | 2001-11-01 | 2011-08-03 | Novartis AG | Sprühtrocknungsverfahren |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
EP1646354A4 (de) * | 2003-07-22 | 2010-03-17 | Baxter Int | Kleine kugelförmige teilchen von niedermolekularen organischen molekülen und herstellungs- und anwendungsverfahren dafür |
JP4210231B2 (ja) * | 2004-03-25 | 2009-01-14 | 株式会社資生堂 | 皮膚のシワを改善する美容方法及びシワ改善具 |
US8728525B2 (en) | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
WO2006103671A1 (en) * | 2005-03-31 | 2006-10-05 | Rafael Armament Development Authority Ltd. | Apparatus for treating particles and liquids by ultrasound |
WO2007016435A2 (en) * | 2005-07-28 | 2007-02-08 | Isp Investments Inc. | Method to improve characteristics of spray dried powders and granulated materials, and the products thereby produced |
WO2007086039A1 (en) * | 2006-01-27 | 2007-08-02 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin | A method of producing porous microparticles |
JP5118139B2 (ja) | 2006-08-04 | 2013-01-16 | バクスター・インターナショナル・インコーポレイテッド | 新規発症自己免疫性糖尿病を予防および/または逆転させるためのマイクロスフィアに基づく組成物 |
DE202006018609U1 (de) * | 2006-08-29 | 2007-05-16 | Euro-Celtique S.A. | Verwendung von Opioidformulierungen in nadellosen Vorrichtungen zur Medikamentenverabreichung |
US20080085315A1 (en) * | 2006-10-10 | 2008-04-10 | John Alfred Doney | Amorphous ezetimibe and the production thereof |
US20080152717A1 (en) * | 2006-12-14 | 2008-06-26 | Isp Investments, Inc. | Amorphous valsartan and the production thereof |
US8613946B2 (en) * | 2006-12-21 | 2013-12-24 | Isp Investment Inc. | Carotenoids of enhanced bioavailability |
CN101622302B (zh) * | 2007-01-26 | 2013-01-23 | Isp投资公司 | 生产喷雾干燥产品的制剂工艺方法 |
ITMI20080807A1 (it) | 2008-05-05 | 2009-11-06 | Antibioticos Spa | Procedimento per la preparazione di tigeciclina in forma amorfa |
US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
US8323615B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
US8367427B2 (en) | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
CN101732259B (zh) * | 2009-12-29 | 2012-08-29 | 广东药学院 | 壳聚糖微米粒及其制备方法和应用 |
US9135998B2 (en) * | 2010-11-09 | 2015-09-15 | Micron Technology, Inc. | Sense operation flags in a memory device |
EP2898894A1 (de) | 2014-01-27 | 2015-07-29 | LTS LOHMANN Therapie-Systeme AG | Nano-in-mikro-Teilchen zur intradermalen Verabreichung |
KR102034872B1 (ko) * | 2018-01-10 | 2019-10-21 | 주식회사 지투지바이오 | 콜라겐 펩타이드가 함유된 폴리카프로락톤 미립구 필러 및 그 제조방법 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3937668A (en) * | 1970-07-15 | 1976-02-10 | Ilse Zolle | Method for incorporating substances into protein microspheres |
CA1077842A (en) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
US4247406A (en) * | 1979-04-23 | 1981-01-27 | Widder Kenneth J | Intravascularly-administrable, magnetically-localizable biodegradable carrier |
US4349530A (en) * | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
US4357254A (en) * | 1981-01-12 | 1982-11-02 | Chemical Sciences, Inc. | Cleaning composition |
FR2505657A1 (fr) * | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
US5707644A (en) * | 1989-11-04 | 1998-01-13 | Danbiosyst Uk Limited | Small particle compositions for intranasal drug delivery |
FR2663224B1 (fr) * | 1990-06-14 | 1995-01-20 | Applicationes Farmaceuticas Sa | Forme galenique parenterale. |
JPH08510989A (ja) * | 1992-10-16 | 1996-11-19 | グラクソ、グループ、リミテッド | ラニチジン組成物 |
TW404844B (en) * | 1993-04-08 | 2000-09-11 | Oxford Biosciences Ltd | Needleless syringe |
US5899880A (en) * | 1994-04-08 | 1999-05-04 | Powderject Research Limited | Needleless syringe using supersonic gas flow for particle delivery |
DK0765157T3 (da) * | 1994-06-15 | 1999-10-25 | Dumex Ltd As | Pellets |
IT1274879B (it) * | 1994-08-03 | 1997-07-25 | Saitec Srl | Apparecchio e metodo per preparare forme farmaceutiche solide a rilascio controllato del principio attivo. |
GB9502879D0 (en) * | 1995-02-14 | 1995-04-05 | Oxford Biosciences Ltd | Particle delivery |
KR100201352B1 (ko) * | 1995-03-16 | 1999-06-15 | 성재갑 | 단일주사 백신 제형 |
US5922253A (en) * | 1995-05-18 | 1999-07-13 | Alkermes Controlled Therapeutics, Inc. | Production scale method of forming microparticles |
US6117449A (en) * | 1996-03-22 | 2000-09-12 | Bio-Sphere Technology, Inc. | Method for inducing a systemic immune response to a hepatitis antigen |
US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
GB9612629D0 (en) * | 1996-06-17 | 1996-08-21 | Oxford Biosciences Ltd | Method for providing dense particle compositions for use in transdermal particle delivery |
-
1998
- 1998-09-03 GB GBGB9819272.7A patent/GB9819272D0/en not_active Ceased
-
1999
- 1999-09-03 WO PCT/GB1999/002930 patent/WO2000013668A1/en active IP Right Grant
- 1999-09-03 BR BR9913456-0A patent/BR9913456A/pt not_active IP Right Cessation
- 1999-09-03 EP EP99943130A patent/EP1107737B1/de not_active Expired - Lifetime
- 1999-09-03 DK DK99943130T patent/DK1107737T3/da active
- 1999-09-03 ES ES04075082T patent/ES2301929T3/es not_active Expired - Lifetime
- 1999-09-03 CN CN99810476A patent/CN1315854A/zh active Pending
- 1999-09-03 AT AT99943130T patent/ATE265204T1/de active
- 1999-09-03 MX MXPA01002323A patent/MXPA01002323A/es unknown
- 1999-09-03 DE DE69938201T patent/DE69938201T2/de not_active Expired - Lifetime
- 1999-09-03 EP EP04075082A patent/EP1410792B1/de not_active Expired - Lifetime
- 1999-09-03 DE DE69916856T patent/DE69916856T2/de not_active Expired - Lifetime
- 1999-09-03 ES ES99943130T patent/ES2223181T3/es not_active Expired - Lifetime
- 1999-09-03 JP JP2000568477A patent/JP2002524411A/ja active Pending
- 1999-09-03 AT AT04075082T patent/ATE386507T1/de not_active IP Right Cessation
- 1999-09-03 CA CA002342206A patent/CA2342206C/en not_active Expired - Fee Related
- 1999-09-03 IL IL14132399A patent/IL141323A0/xx unknown
- 1999-09-03 AU AU56407/99A patent/AU5640799A/en not_active Abandoned
-
2001
- 2001-03-02 US US09/797,181 patent/US20020197325A1/en not_active Abandoned
-
2004
- 2004-07-30 US US10/902,464 patent/US20050002870A1/en not_active Abandoned
-
2005
- 2005-09-26 JP JP2005278375A patent/JP2006096755A/ja active Pending
-
2006
- 2006-10-02 US US11/540,720 patent/US20070026081A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE386507T1 (de) | 2008-03-15 |
CA2342206A1 (en) | 2000-03-16 |
DE69916856D1 (de) | 2004-06-03 |
EP1410792A1 (de) | 2004-04-21 |
EP1107737B1 (de) | 2004-04-28 |
DK1107737T3 (da) | 2004-08-02 |
BR9913456A (pt) | 2001-07-24 |
ES2223181T3 (es) | 2005-02-16 |
DE69938201T2 (de) | 2009-02-12 |
JP2002524411A (ja) | 2002-08-06 |
EP1410792A8 (de) | 2004-12-29 |
AU5640799A (en) | 2000-03-27 |
WO2000013668A1 (en) | 2000-03-16 |
US20020197325A1 (en) | 2002-12-26 |
CA2342206C (en) | 2006-12-12 |
MXPA01002323A (es) | 2002-05-08 |
DE69916856T2 (de) | 2005-04-21 |
US20050002870A1 (en) | 2005-01-06 |
ES2301929T3 (es) | 2008-07-01 |
GB9819272D0 (en) | 1998-10-28 |
JP2006096755A (ja) | 2006-04-13 |
IL141323A0 (en) | 2002-03-10 |
DE69938201D1 (de) | 2008-04-03 |
EP1107737A1 (de) | 2001-06-20 |
US20070026081A1 (en) | 2007-02-01 |
EP1410792B1 (de) | 2008-02-20 |
CN1315854A (zh) | 2001-10-03 |
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