ATE253079T1 - Methoden zur aufreinigung von authentischem igf aus hefewirtszellen - Google Patents
Methoden zur aufreinigung von authentischem igf aus hefewirtszellenInfo
- Publication number
- ATE253079T1 ATE253079T1 AT96919305T AT96919305T ATE253079T1 AT E253079 T1 ATE253079 T1 AT E253079T1 AT 96919305 T AT96919305 T AT 96919305T AT 96919305 T AT96919305 T AT 96919305T AT E253079 T1 ATE253079 T1 AT E253079T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- host cells
- yeast host
- purifying
- authentic igf
- Prior art date
Links
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 3
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/477,984 US7193042B1 (en) | 1995-06-07 | 1995-06-07 | Methods for purifying authentic IGF from yeast hosts |
US66348196A | 1996-06-06 | 1996-06-06 | |
PCT/US1996/009828 WO1996040776A1 (en) | 1995-06-07 | 1996-06-07 | Methods for purifying authentic igf from yeast hosts |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE253079T1 true ATE253079T1 (de) | 2003-11-15 |
Family
ID=27045743
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96919305T ATE253079T1 (de) | 1995-06-07 | 1996-06-07 | Methoden zur aufreinigung von authentischem igf aus hefewirtszellen |
Country Status (7)
Country | Link |
---|---|
US (1) | US6117983A (de) |
EP (1) | EP0832121B1 (de) |
JP (3) | JP2002514890A (de) |
AT (1) | ATE253079T1 (de) |
AU (1) | AU6167596A (de) |
DE (1) | DE69630524T2 (de) |
WO (1) | WO1996040776A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7071313B1 (en) * | 1995-06-07 | 2006-07-04 | Cephalon, Inc. | Methods of purifying authentic IGF from yeast hosts |
US7193042B1 (en) * | 1995-06-07 | 2007-03-20 | Chiron Corporation | Methods for purifying authentic IGF from yeast hosts |
AU8688798A (en) | 1997-08-05 | 1999-03-01 | Chiron Corporation | Novel (pichia pastoris) gene sequences and methods for their use |
US7067485B2 (en) | 1997-11-07 | 2006-06-27 | Chiron Corporation | IGF-I composition and its use |
PT1084136E (pt) | 1998-06-01 | 2004-12-31 | Genentech Inc | Separacao de monomeros de anticorpos dos seus multimeros atraves da utilizacao de cromatografia de troca ionica |
US6605450B1 (en) | 2000-05-25 | 2003-08-12 | Chiron Corporation | Iron regulation of the PpSEC10 transcriptional regulatory region of Pichia pastoris and methods of use |
US20030212248A1 (en) * | 2000-07-12 | 2003-11-13 | Furman Thomas Charles | Process to increase protein stability |
AU2003901507A0 (en) * | 2003-03-28 | 2003-04-17 | Norika Holdings | Process for isolating a pharmaceutical product |
EP1988154B1 (de) * | 2007-04-30 | 2013-08-21 | Ajinomoto Co., Inc. | Verfahren zur Herstellung des humanen insulinähnlichen Wachstumsfaktors I |
EP2670773A1 (de) | 2011-02-01 | 2013-12-11 | Novo Nordisk A/S | Reinigung von insulin |
WO2020142305A1 (en) | 2018-12-31 | 2020-07-09 | Omnigen Research, Llc | Feed supplements |
UY39268A (es) | 2020-06-12 | 2022-01-31 | Phibro Animal Health Corporation | Composición o combinación que comprende un suplemento nutricional aniónico y 25-hidroxi vitamina d |
WO2023192262A1 (en) | 2022-04-01 | 2023-10-05 | Phibro Animal Health Corporation | A combination comprising bacillus and an essential oil and methods for making and using |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0548267A4 (en) * | 1990-09-04 | 1994-11-23 | Salk Inst Biotech Ind | Production of insulin-like growth factor-1 in methylotrophic yeast cells |
US5231178A (en) * | 1991-01-16 | 1993-07-27 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Method for the purification of intact, correctly-folded insulin-like growth factor-1 |
US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
EP0586667A1 (de) * | 1992-03-24 | 1994-03-16 | Synergen, Inc. | Rückfaltung und Reinigung von insulinähnlichen Wachstumsfaktor I |
US5407810A (en) * | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
US5663304A (en) * | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
US5451660A (en) * | 1993-12-13 | 1995-09-19 | Genentech, Inc. | Method for purifying polypeptides |
US5446024A (en) * | 1993-12-17 | 1995-08-29 | Genentech, Inc. | Purification of insulin-like growth factor |
EP0779927A1 (de) * | 1994-09-08 | 1997-06-25 | Chiron Corporation | Methode zur gesteigerten herstellung von insulin-ähnlichem wachstumsfaktor |
US5650496A (en) * | 1995-04-14 | 1997-07-22 | Cephalon, Inc. | IGF-I purification process |
-
1996
- 1996-06-07 JP JP50203297A patent/JP2002514890A/ja not_active Withdrawn
- 1996-06-07 DE DE69630524T patent/DE69630524T2/de not_active Expired - Fee Related
- 1996-06-07 WO PCT/US1996/009828 patent/WO1996040776A1/en active IP Right Grant
- 1996-06-07 EP EP96919305A patent/EP0832121B1/de not_active Expired - Lifetime
- 1996-06-07 AT AT96919305T patent/ATE253079T1/de not_active IP Right Cessation
- 1996-06-07 AU AU61675/96A patent/AU6167596A/en not_active Abandoned
-
1997
- 1997-12-15 US US08/990,490 patent/US6117983A/en not_active Expired - Fee Related
-
2005
- 2005-06-07 JP JP2005167580A patent/JP2005253475A/ja not_active Ceased
-
2007
- 2007-11-16 JP JP2007298684A patent/JP2008054693A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2002514890A (ja) | 2002-05-21 |
JP2008054693A (ja) | 2008-03-13 |
DE69630524T2 (de) | 2004-08-05 |
US6117983A (en) | 2000-09-12 |
WO1996040776A1 (en) | 1996-12-19 |
EP0832121A1 (de) | 1998-04-01 |
JP2005253475A (ja) | 2005-09-22 |
EP0832121B1 (de) | 2003-10-29 |
DE69630524D1 (de) | 2003-12-11 |
AU6167596A (en) | 1996-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |