DE69630524D1 - Methoden zur aufreinigung von authentischem igf aus hefewirtszellen - Google Patents

Methoden zur aufreinigung von authentischem igf aus hefewirtszellen

Info

Publication number
DE69630524D1
DE69630524D1 DE69630524T DE69630524T DE69630524D1 DE 69630524 D1 DE69630524 D1 DE 69630524D1 DE 69630524 T DE69630524 T DE 69630524T DE 69630524 T DE69630524 T DE 69630524T DE 69630524 D1 DE69630524 D1 DE 69630524D1
Authority
DE
Germany
Prior art keywords
methods
farms
year
purifying
authentic igf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69630524T
Other languages
English (en)
Other versions
DE69630524T2 (de
Inventor
Cynthia Cowgill
Luis Juarbe
Patricio Riquelme
Glenn Dorin
M Bussineau
D Kudrna
G Otzurk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Cephalon LLC
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/477,984 external-priority patent/US7193042B1/en
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69630524D1 publication Critical patent/DE69630524D1/de
Application granted granted Critical
Publication of DE69630524T2 publication Critical patent/DE69630524T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
DE69630524T 1995-06-07 1996-06-07 Methoden zur aufreinigung von authentischem igf aus hefewirtszellen Expired - Fee Related DE69630524T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US477984 1995-06-07
US08/477,984 US7193042B1 (en) 1995-06-07 1995-06-07 Methods for purifying authentic IGF from yeast hosts
US66348196A 1996-06-06 1996-06-06
US663481 1996-06-06
PCT/US1996/009828 WO1996040776A1 (en) 1995-06-07 1996-06-07 Methods for purifying authentic igf from yeast hosts

Publications (2)

Publication Number Publication Date
DE69630524D1 true DE69630524D1 (de) 2003-12-11
DE69630524T2 DE69630524T2 (de) 2004-08-05

Family

ID=27045743

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69630524T Expired - Fee Related DE69630524T2 (de) 1995-06-07 1996-06-07 Methoden zur aufreinigung von authentischem igf aus hefewirtszellen

Country Status (7)

Country Link
US (1) US6117983A (de)
EP (1) EP0832121B1 (de)
JP (3) JP2002514890A (de)
AT (1) ATE253079T1 (de)
AU (1) AU6167596A (de)
DE (1) DE69630524T2 (de)
WO (1) WO1996040776A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7193042B1 (en) * 1995-06-07 2007-03-20 Chiron Corporation Methods for purifying authentic IGF from yeast hosts
US7071313B1 (en) * 1995-06-07 2006-07-04 Cephalon, Inc. Methods of purifying authentic IGF from yeast hosts
WO1999007862A1 (en) 1997-08-05 1999-02-18 Chiron Corporation Novel pichia pastoris gene sequences and methods for their use
US7067485B2 (en) 1997-11-07 2006-06-27 Chiron Corporation IGF-I composition and its use
PT1084136E (pt) 1998-06-01 2004-12-31 Genentech Inc Separacao de monomeros de anticorpos dos seus multimeros atraves da utilizacao de cromatografia de troca ionica
US6605450B1 (en) 2000-05-25 2003-08-12 Chiron Corporation Iron regulation of the PpSEC10 transcriptional regulatory region of Pichia pastoris and methods of use
US20030212248A1 (en) * 2000-07-12 2003-11-13 Furman Thomas Charles Process to increase protein stability
AU2003901507A0 (en) * 2003-03-28 2003-04-17 Norika Holdings Process for isolating a pharmaceutical product
EP1988154B1 (de) * 2007-04-30 2013-08-21 Ajinomoto Co., Inc. Verfahren zur Herstellung des humanen insulinähnlichen Wachstumsfaktors I
RU2603752C2 (ru) * 2011-02-01 2016-11-27 Ново Нордиск А/С Очистка инсулина
MX2021007908A (es) 2018-12-31 2021-09-08 Omnigen Res Llc Suplementos alimenticios.
US11723919B2 (en) 2020-06-12 2023-08-15 Phibro Animal Health Corporation Composition or combination comprising anionic dietary supplement and 25-hydroxy vitamin D
WO2023192262A1 (en) 2022-04-01 2023-10-05 Phibro Animal Health Corporation A combination comprising bacillus and an essential oil and methods for making and using

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004363A1 (en) * 1990-09-04 1992-03-19 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5231178A (en) * 1991-01-16 1993-07-27 The Salk Institute Biotechnology/Industrial Associates, Inc. Method for the purification of intact, correctly-folded insulin-like growth factor-1
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
EP0586667A1 (de) * 1992-03-24 1994-03-16 Synergen, Inc. Rückfaltung und Reinigung von insulinähnlichen Wachstumsfaktor I
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5451660A (en) * 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
US5446024A (en) * 1993-12-17 1995-08-29 Genentech, Inc. Purification of insulin-like growth factor
EP0779927A1 (de) * 1994-09-08 1997-06-25 Chiron Corporation Methode zur gesteigerten herstellung von insulin-ähnlichem wachstumsfaktor
US5650496A (en) * 1995-04-14 1997-07-22 Cephalon, Inc. IGF-I purification process

Also Published As

Publication number Publication date
US6117983A (en) 2000-09-12
JP2005253475A (ja) 2005-09-22
ATE253079T1 (de) 2003-11-15
JP2008054693A (ja) 2008-03-13
WO1996040776A1 (en) 1996-12-19
AU6167596A (en) 1996-12-30
DE69630524T2 (de) 2004-08-05
JP2002514890A (ja) 2002-05-21
EP0832121B1 (de) 2003-10-29
EP0832121A1 (de) 1998-04-01

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: CHIRON CORP., EMERYVILLE, CALIF., US

Owner name: CEPHALON, INC., WEST CHESTER, PA., US

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CEPHALON, INC., WEST CHESTER, PA., US

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US

8339 Ceased/non-payment of the annual fee