NO970740L - Glutamat reseptor - Google Patents
Glutamat reseptorInfo
- Publication number
- NO970740L NO970740L NO970740A NO970740A NO970740L NO 970740 L NO970740 L NO 970740L NO 970740 A NO970740 A NO 970740A NO 970740 A NO970740 A NO 970740A NO 970740 L NO970740 L NO 970740L
- Authority
- NO
- Norway
- Prior art keywords
- protein
- glutamate receptor
- hmglur
- nucleic acids
- host cells
- Prior art date
Links
- 102000018899 Glutamate Receptors Human genes 0.000 title 1
- 108010027915 Glutamate Receptors Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000016193 Metabotropic glutamate receptors Human genes 0.000 abstract 1
- 108010010914 Metabotropic glutamate receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
En human metabotropisk glutamatreseptor (hmGluR) subtype, isolerte nukleinsyrer kodende for denne, vertsceller som produserer et protein, fremgangsmåter for fremstilling av slikt protein, nukleinsyrer og vertsceller, anvendelser derav og antistoffer rettet mot et hmGluR-proteln, er beskrevet.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9416554A GB9416554D0 (en) | 1994-08-19 | 1994-08-19 | Glutamate receptor |
PCT/EP1995/002728 WO1996006167A1 (en) | 1994-08-19 | 1995-07-12 | Glutamate receptor |
Publications (2)
Publication Number | Publication Date |
---|---|
NO970740D0 NO970740D0 (no) | 1997-02-18 |
NO970740L true NO970740L (no) | 1997-04-14 |
Family
ID=10759939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO970740A NO970740L (no) | 1994-08-19 | 1997-02-18 | Glutamat reseptor |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0776364A1 (no) |
JP (1) | JPH10504198A (no) |
AU (1) | AU3110095A (no) |
CA (1) | CA2196997A1 (no) |
FI (1) | FI970633A0 (no) |
GB (1) | GB9416554D0 (no) |
HU (1) | HUT76969A (no) |
NO (1) | NO970740L (no) |
WO (1) | WO1996006167A1 (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5912122A (en) * | 1993-06-04 | 1999-06-15 | Sibia Neurosciences, Inc. | Nucleic acids encoding and method for detecting nucleic acid encoding human metabotropic glutamate receptor subtype mGluR6 |
EP0720650B1 (en) | 1993-09-20 | 2004-12-01 | Novartis AG | Human metabotropic glutamate receptor subtype hmglur7 and related dna compounds |
US6017697A (en) * | 1994-11-14 | 2000-01-25 | Eli Lilly And Company | Excitatory amino acid receptor protein and related nucleic acid compounds |
WO1999021992A2 (en) * | 1997-10-23 | 1999-05-06 | Ganimed Pharmaceuticals Gmbh | Nucleic acid molecules encoding a glutamate receptor |
US7262280B1 (en) | 1998-04-03 | 2007-08-28 | Nps Pharmaceuticals, Inc. | G-protein fusion receptors and constructs encoding same |
GB9807722D0 (en) * | 1998-04-08 | 1998-06-10 | Smithkline Beecham Plc | Novel compounds |
AU3952699A (en) * | 1998-05-19 | 1999-12-06 | Compugen Ltd. | Metabotropic glutamate receptor-like protein and encoding cdna |
EP1546201A4 (en) * | 2002-09-11 | 2006-08-16 | Merck & Co Inc | NUCLEIC ACID SEQUENCES CODING TO MGLUR2 AND MGLUR3 FOR NEW POINT MUTATIONS |
WO2005076014A1 (en) * | 2004-01-28 | 2005-08-18 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human metabotropic glutamate receptor 2 (mglur2) |
TWI417095B (zh) | 2006-03-15 | 2013-12-01 | Janssen Pharmaceuticals Inc | 1,4-二取代之3-氰基-吡啶酮衍生物及其作為mGluR2-受體之正向異位性調節劑之用途 |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
US9114138B2 (en) | 2007-09-14 | 2015-08-25 | Janssen Pharmaceuticals, Inc. | 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′] bipyridinyl-2′-ones |
WO2010025890A1 (en) | 2008-09-02 | 2010-03-11 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
AU2009319387B2 (en) | 2008-11-28 | 2012-05-10 | Addex Pharma S.A. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
CA2760259C (en) | 2009-05-12 | 2018-05-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
JP5634506B2 (ja) | 2009-05-12 | 2014-12-03 | ジャンセン ファーマシューティカルズ, インコーポレイテッド | 1,2,3−トリアゾロ[4,3−a]ピリジン誘導体ならびに神経障害および精神障害の治療または予防のためのその使用 |
ES2552455T3 (es) | 2010-11-08 | 2015-11-30 | Janssen Pharmaceuticals, Inc. | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2 |
JP5852665B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
JP5852666B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
LT3096790T (lt) | 2014-01-21 | 2019-10-10 | Janssen Pharmaceutica, N.V. | Deriniai, apimantys 2 potipio metabotropinio glutamaterginio receptoriaus teigiamus alosterinius moduliatorius arba ortosterinius agonistus, ir jų panaudojimas |
WO2015110435A1 (en) | 2014-01-21 | 2015-07-30 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL105587A0 (en) * | 1992-05-08 | 1993-09-22 | Lilly Co Eli | Human metabotropic glutamate receptor and related dna compounds |
US5521297A (en) * | 1993-06-04 | 1996-05-28 | Salk Institute Biotechnology/Industrial Associates | Nucleic acids encoding human metabotropic glutamate receptors |
-
1994
- 1994-08-19 GB GB9416554A patent/GB9416554D0/en active Pending
-
1995
- 1995-07-12 CA CA 2196997 patent/CA2196997A1/en not_active Abandoned
- 1995-07-12 JP JP8507725A patent/JPH10504198A/ja active Pending
- 1995-07-12 AU AU31100/95A patent/AU3110095A/en not_active Abandoned
- 1995-07-12 HU HU9701680A patent/HUT76969A/hu unknown
- 1995-07-12 WO PCT/EP1995/002728 patent/WO1996006167A1/en not_active Application Discontinuation
- 1995-07-12 EP EP95926863A patent/EP0776364A1/en not_active Withdrawn
-
1997
- 1997-02-14 FI FI970633A patent/FI970633A0/fi unknown
- 1997-02-18 NO NO970740A patent/NO970740L/no unknown
Also Published As
Publication number | Publication date |
---|---|
GB9416554D0 (en) | 1994-10-12 |
AU3110095A (en) | 1996-03-14 |
NO970740D0 (no) | 1997-02-18 |
FI970633A (fi) | 1997-02-14 |
MX9701267A (es) | 1997-11-29 |
EP0776364A1 (en) | 1997-06-04 |
JPH10504198A (ja) | 1998-04-28 |
WO1996006167A1 (en) | 1996-02-29 |
FI970633A0 (fi) | 1997-02-14 |
CA2196997A1 (en) | 1996-02-29 |
HUT76969A (hu) | 1998-01-28 |
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