ATE252906T1 - Pharmazeutische formulierung, die ein beta- lactamase hemmendes penem in kombination mit einem beta-laktam-antibiotikum enthalten und ihre verwendung zur behandlung von bakteriellen infektionen - Google Patents

Pharmazeutische formulierung, die ein beta- lactamase hemmendes penem in kombination mit einem beta-laktam-antibiotikum enthalten und ihre verwendung zur behandlung von bakteriellen infektionen

Info

Publication number
ATE252906T1
ATE252906T1 AT95917949T AT95917949T ATE252906T1 AT E252906 T1 ATE252906 T1 AT E252906T1 AT 95917949 T AT95917949 T AT 95917949T AT 95917949 T AT95917949 T AT 95917949T AT E252906 T1 ATE252906 T1 AT E252906T1
Authority
AT
Austria
Prior art keywords
beta
penem
combination
pharmaceutical formulation
lactam antibiotic
Prior art date
Application number
AT95917949T
Other languages
English (en)
Inventor
K Coleman
J E Neale
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9408161A external-priority patent/GB9408161D0/en
Priority claimed from GB9408164A external-priority patent/GB9408164D0/en
Priority claimed from GB9408163A external-priority patent/GB9408163D0/en
Priority claimed from GB9408162A external-priority patent/GB9408162D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE252906T1 publication Critical patent/ATE252906T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT95917949T 1994-04-25 1995-04-22 Pharmazeutische formulierung, die ein beta- lactamase hemmendes penem in kombination mit einem beta-laktam-antibiotikum enthalten und ihre verwendung zur behandlung von bakteriellen infektionen ATE252906T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9408161A GB9408161D0 (en) 1994-04-25 1994-04-25 Pharmaceutical formulations
GB9408164A GB9408164D0 (en) 1994-04-25 1994-04-25 Pharmaceutical formulations
GB9408163A GB9408163D0 (en) 1994-04-25 1994-04-25 Pharmaceutical formulations
GB9408162A GB9408162D0 (en) 1994-04-25 1994-04-25 Pharmaceutical formulations
PCT/EP1995/001546 WO1995028935A1 (en) 1994-04-25 1995-04-22 Pharmaceutical formulations containing a beta-lactamase inhibiting penem in combination with a beta-lactam antibiotic and their use in the treatment of bacterial infections

Publications (1)

Publication Number Publication Date
ATE252906T1 true ATE252906T1 (de) 2003-11-15

Family

ID=27451150

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95917949T ATE252906T1 (de) 1994-04-25 1995-04-22 Pharmazeutische formulierung, die ein beta- lactamase hemmendes penem in kombination mit einem beta-laktam-antibiotikum enthalten und ihre verwendung zur behandlung von bakteriellen infektionen

Country Status (17)

Country Link
US (3) US5911985A (de)
EP (1) EP0758240B1 (de)
JP (2) JP3865770B2 (de)
KR (1) KR100363604B1 (de)
CN (1) CN1094353C (de)
AT (1) ATE252906T1 (de)
AU (1) AU690685B2 (de)
BR (1) BR9507521A (de)
CZ (1) CZ286898B6 (de)
DE (1) DE69532032T2 (de)
ES (1) ES2206502T3 (de)
HU (1) HUT76340A (de)
MX (1) MX9605149A (de)
NO (1) NO964500L (de)
NZ (1) NZ285085A (de)
PL (1) PL179415B1 (de)
WO (1) WO1995028935A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472383B1 (en) 1994-04-25 2002-10-29 Smithkline Beecham P.L.C. Pharmaceutical formulations
EP1199077A1 (de) * 2000-10-19 2002-04-24 Amura Limited Stabilisierte Oxapenem-3-carbonsäure enthaltende Arzneimittel durch Gefriergetrocknen mit pharmazeutischen Trägern
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039476A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp Proceso para preparar derivados de 6-alquiliden penem
TW200716104A (en) * 2005-06-01 2007-05-01 Wyeth Corp Tricyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
TW200716102A (en) * 2005-06-01 2007-05-01 Wyeth Corp Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
WO2007027323A2 (en) * 2005-07-27 2007-03-08 Wyeth TRICYCLIC 6-ALKYLIDENE-PENEM β-LACTAMASE INHIBITORS AND β-LACTAM ANTIBIOTIC COMBINATION: A BROAD SPECTRUM ANTIBIOTIC
KR20080032637A (ko) * 2005-07-27 2008-04-15 와이어쓰 이환식 6-알킬리덴-페넴 β-락타마제 저해제 및 β-락탐항생제 조합: 광범위 항생제
GT200600380A (es) * 2005-08-24 2007-03-29 Proceso para la preparacion de inhibidores de beta-lactamasa

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
EP0018203B1 (de) * 1979-04-21 1983-03-02 Beecham Group Plc Clavulansäure-Derivate, ihre Herstellung und Verwendung in Arzneimitteln
EP0041768B1 (de) * 1980-04-24 1987-11-11 Beecham Group Plc Beta-Lactam-Verbindungen, ihre Herstellung und Verwendung
EP0120613A1 (de) * 1983-03-02 1984-10-03 Beecham Group Plc Penem-Derivate und Vorstufenverbindungen
GB8518421D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
GB8518422D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
GB8518416D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
ZA865573B (en) * 1985-07-27 1987-03-25 Sumitomo Metal Ind Method of gasifying solid carbonaceous materials and apparatus therefor
GB9222700D0 (en) * 1992-10-29 1992-12-09 Smithkline Beecham Plc Chemical compounds

Also Published As

Publication number Publication date
DE69532032T2 (de) 2004-07-22
NO964500L (no) 1996-11-26
HUT76340A (en) 1997-08-28
NO964500D0 (no) 1996-10-23
EP0758240B1 (de) 2003-10-29
WO1995028935A1 (en) 1995-11-02
JPH09512260A (ja) 1997-12-09
PL179415B1 (pl) 2000-09-29
US5939066A (en) 1999-08-17
AU2407395A (en) 1995-11-16
AU690685B2 (en) 1998-04-30
CZ286898B6 (en) 2000-07-12
CN1149254A (zh) 1997-05-07
US5776455A (en) 1998-07-07
DE69532032D1 (de) 2003-12-04
CZ315696A3 (en) 1997-06-11
PL317045A1 (en) 1997-03-03
KR100363604B1 (ko) 2003-04-11
HU9602928D0 (en) 1996-12-30
CN1094353C (zh) 2002-11-20
JP2005298525A (ja) 2005-10-27
BR9507521A (pt) 1997-09-16
US5911985A (en) 1999-06-15
ES2206502T3 (es) 2004-05-16
JP3865770B2 (ja) 2007-01-10
NZ285085A (en) 1998-04-27
EP0758240A1 (de) 1997-02-19
KR970702723A (ko) 1997-06-10
MX9605149A (es) 1997-12-31

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties