ATE247173T1 - Charakterisierung von polypeptiden - Google Patents
Charakterisierung von polypeptidenInfo
- Publication number
- ATE247173T1 ATE247173T1 AT98900949T AT98900949T ATE247173T1 AT E247173 T1 ATE247173 T1 AT E247173T1 AT 98900949 T AT98900949 T AT 98900949T AT 98900949 T AT98900949 T AT 98900949T AT E247173 T1 ATE247173 T1 AT E247173T1
- Authority
- AT
- Austria
- Prior art keywords
- terminus
- pct
- cleavage site
- sequence
- population
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6818—Sequencing of polypeptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9701357.7A GB9701357D0 (en) | 1997-01-23 | 1997-01-23 | Characterising polypeptides |
GBGB9726947.6A GB9726947D0 (en) | 1997-12-19 | 1997-12-19 | Characterising polypeptides |
PCT/GB1998/000201 WO1998032876A1 (en) | 1997-01-23 | 1998-01-23 | Characterising polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE247173T1 true ATE247173T1 (de) | 2003-08-15 |
Family
ID=26310845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98900949T ATE247173T1 (de) | 1997-01-23 | 1998-01-23 | Charakterisierung von polypeptiden |
Country Status (12)
Country | Link |
---|---|
US (1) | US6156527A (de) |
EP (1) | EP1027454B1 (de) |
JP (1) | JP3795534B2 (de) |
CN (1) | CN1118580C (de) |
AT (1) | ATE247173T1 (de) |
AU (1) | AU721390B2 (de) |
CA (1) | CA2278556C (de) |
DE (1) | DE69817211T2 (de) |
ES (1) | ES2205437T3 (de) |
IL (1) | IL130949A (de) |
NZ (1) | NZ336768A (de) |
WO (1) | WO1998032876A1 (de) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6207370B1 (en) | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
ATE253126T1 (de) | 1998-08-25 | 2003-11-15 | Univ Washington | Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen |
GB9821393D0 (en) * | 1998-10-01 | 1998-11-25 | Brax Genomics Ltd | Protein profiling 2 |
EP1311858B1 (de) * | 2000-05-05 | 2006-11-02 | Purdue Research Foundation | Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen |
EP1295123A4 (de) | 2000-06-12 | 2005-02-02 | Univ Washington | Selektives markieren und isolieren von phosphopeptiden und anwendungen in proteomischen analysen |
CA2419159A1 (en) * | 2000-08-11 | 2002-02-21 | Agilix Corporation | Ultra-sensitive detection systems |
US7583710B2 (en) | 2001-01-30 | 2009-09-01 | Board Of Trustees Operating Michigan State University | Laser and environmental monitoring system |
WO2002061799A2 (en) * | 2001-01-30 | 2002-08-08 | Board Of Trustees Operating Michigan State University | Control system and apparatus for use with laser excitation or ionization |
US7567596B2 (en) | 2001-01-30 | 2009-07-28 | Board Of Trustees Of Michigan State University | Control system and apparatus for use with ultra-fast laser |
US7609731B2 (en) * | 2001-01-30 | 2009-10-27 | Board Of Trustees Operating Michigan State University | Laser system using ultra-short laser pulses |
US7450618B2 (en) * | 2001-01-30 | 2008-11-11 | Board Of Trustees Operating Michigan State University | Laser system using ultrashort laser pulses |
US7973936B2 (en) | 2001-01-30 | 2011-07-05 | Board Of Trustees Of Michigan State University | Control system and apparatus for use with ultra-fast laser |
US20020106700A1 (en) * | 2001-02-05 | 2002-08-08 | Foote Robert S. | Method for analyzing proteins |
DE60215498T2 (de) * | 2001-06-07 | 2007-04-26 | Electrophoretics Ltd., Cobham | Verfahren zur bestimmung von polypeptiden |
EP1267170A1 (de) * | 2001-06-07 | 2002-12-18 | Xzillion GmbH & CO.KG | Verfahren zur Charakterisierung von Polypeptiden |
US6800449B1 (en) * | 2001-07-13 | 2004-10-05 | Syngenta Participations Ag | High throughput functional proteomics |
CA2461587C (en) | 2001-09-27 | 2011-04-26 | Purdue Research Foundation | Materials and methods for controlling isotope effects during fractionation of analytes |
US20030124595A1 (en) * | 2001-11-06 | 2003-07-03 | Lizardi Paul M. | Sensitive coded detection systems |
AU2003224253A1 (en) | 2002-04-04 | 2003-10-27 | Electrophoretics Limited | Method for characterising analytes |
US7094345B2 (en) * | 2002-09-09 | 2006-08-22 | Cytonome, Inc. | Implementation of microfluidic components, including molecular fractionation devices, in a microfluidic system |
CA2488584C (en) * | 2003-01-30 | 2011-10-11 | Applera Corporation | Methods, mixtures, kits and compositions pertaining to analyte determination |
WO2004108948A2 (en) * | 2003-06-04 | 2004-12-16 | President And Fellows Of Harvard College | Systems, methods and kits for characterizing phosphoproteomes |
WO2005042559A2 (en) * | 2003-06-06 | 2005-05-12 | President And Fellows Of Harvard College | Capture and release based isotope tagged peptides and methods for using the same |
US7579165B2 (en) * | 2003-10-16 | 2009-08-25 | Shimadzu Corporation | Methods for derivatizing protein or peptide with sulfonic acid groups |
JP4576972B2 (ja) * | 2003-10-16 | 2010-11-10 | 株式会社島津製作所 | タンパク質又はペプチドのスルホン酸誘導体化されたn末端ペプチドフラグメントを質量分析する方法 |
US20050148087A1 (en) * | 2004-01-05 | 2005-07-07 | Applera Corporation | Isobarically labeled analytes and fragment ions derived therefrom |
US20050147985A1 (en) * | 2004-01-05 | 2005-07-07 | Applera Corporation | Mixtures of isobarically labeled analytes and fragments ions derived therefrom |
US20050148771A1 (en) * | 2004-01-05 | 2005-07-07 | Applera Corporation. | Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof |
US7355045B2 (en) * | 2004-01-05 | 2008-04-08 | Applera Corporation | Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof |
JP2006078192A (ja) * | 2004-09-07 | 2006-03-23 | Shimadzu Corp | 生体高分子の質量分析法 |
WO2006084130A2 (en) * | 2005-02-03 | 2006-08-10 | Perkinelmer Las, Inc. | Ultra-sensitive detection systems using multidimension signals |
EP1851532A1 (de) | 2005-02-14 | 2007-11-07 | Board of Trustees of Michigan State University | Ultraschnelles lasersystem |
GB0515323D0 (en) | 2005-07-26 | 2005-08-31 | Electrophoretics Ltd | Mass labels |
GB0518585D0 (en) | 2005-09-12 | 2005-10-19 | Electrophoretics Ltd | Mass labels |
WO2007064703A2 (en) | 2005-11-30 | 2007-06-07 | Board Of Trustees Of Michigan State University | Laser based identification of molecular characteristics |
US9018562B2 (en) | 2006-04-10 | 2015-04-28 | Board Of Trustees Of Michigan State University | Laser material processing system |
US20090002703A1 (en) * | 2006-08-16 | 2009-01-01 | Craig Edward Parman | Methods and systems for quantifying isobaric labels and peptides |
US20100298153A1 (en) * | 2006-09-14 | 2010-11-25 | Koninklijke Philips Electronics N.V. | Methods for analysing protein samples based on the identification of c-terminal peptides |
US8334506B2 (en) | 2007-12-10 | 2012-12-18 | 1St Detect Corporation | End cap voltage control of ion traps |
US7973277B2 (en) | 2008-05-27 | 2011-07-05 | 1St Detect Corporation | Driving a mass spectrometer ion trap or mass filter |
US8861075B2 (en) | 2009-03-05 | 2014-10-14 | Board Of Trustees Of Michigan State University | Laser amplification system |
EP2336783A1 (de) * | 2009-12-18 | 2011-06-22 | Basf Se | C-terminale Sequenzierung von Aminosäuren |
US8630322B2 (en) | 2010-03-01 | 2014-01-14 | Board Of Trustees Of Michigan State University | Laser system for output manipulation |
US11435358B2 (en) | 2011-06-23 | 2022-09-06 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
GB2577626B (en) | 2011-06-23 | 2020-09-23 | Univ Texas | Identifying peptides at the single molecule level |
US20150087526A1 (en) * | 2012-01-24 | 2015-03-26 | The Regents Of The University Of Colorado, A Body Corporate | Peptide identification and sequencing by single-molecule detection of peptides undergoing degradation |
CA2961493C (en) | 2014-09-15 | 2023-10-03 | Board Of Regents, The University Of Texas System | Improved single molecule peptide sequencing |
CN106153712B (zh) * | 2015-04-16 | 2019-02-12 | 深圳华大生命科学研究院 | 一种多肽二硫键的定位方法 |
CN112739708A (zh) * | 2018-08-14 | 2021-04-30 | 德克萨斯大学系统董事会 | 对与主要组织相容性复合体结合的肽进行单分子测序 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4532207A (en) * | 1982-03-19 | 1985-07-30 | G. D. Searle & Co. | Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase |
SE8803986D0 (sv) * | 1988-11-03 | 1988-11-03 | Pharmacia Ab | Method for sequencing peptides or proteins |
JPH0824576B2 (ja) * | 1992-07-22 | 1996-03-13 | 農林水産省食品総合研究所長 | 新規アスパラギニルエンドプロテアーゼとその製造法並びに利用法 |
US5470703A (en) * | 1992-10-21 | 1995-11-28 | Shimadzu Corporation | Method for peptide C-terminal fragment sequence analysis and apparatus for collecting peptide fragment |
-
1998
- 1998-01-23 IL IL13094998A patent/IL130949A/en not_active IP Right Cessation
- 1998-01-23 WO PCT/GB1998/000201 patent/WO1998032876A1/en active IP Right Grant
- 1998-01-23 AU AU56745/98A patent/AU721390B2/en not_active Ceased
- 1998-01-23 US US09/341,993 patent/US6156527A/en not_active Expired - Lifetime
- 1998-01-23 CN CN98801977.9A patent/CN1118580C/zh not_active Expired - Fee Related
- 1998-01-23 JP JP53172898A patent/JP3795534B2/ja not_active Expired - Fee Related
- 1998-01-23 NZ NZ336768A patent/NZ336768A/en unknown
- 1998-01-23 DE DE69817211T patent/DE69817211T2/de not_active Expired - Lifetime
- 1998-01-23 ES ES98900949T patent/ES2205437T3/es not_active Expired - Lifetime
- 1998-01-23 EP EP98900949A patent/EP1027454B1/de not_active Expired - Lifetime
- 1998-01-23 CA CA002278556A patent/CA2278556C/en not_active Expired - Fee Related
- 1998-01-23 AT AT98900949T patent/ATE247173T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2001508872A (ja) | 2001-07-03 |
DE69817211D1 (de) | 2003-09-18 |
US6156527A (en) | 2000-12-05 |
IL130949A (en) | 2004-12-15 |
EP1027454A1 (de) | 2000-08-16 |
CA2278556A1 (en) | 1998-07-30 |
AU721390B2 (en) | 2000-06-29 |
CN1244218A (zh) | 2000-02-09 |
AU5674598A (en) | 1998-08-18 |
WO1998032876A1 (en) | 1998-07-30 |
CN1118580C (zh) | 2003-08-20 |
NZ336768A (en) | 2001-12-21 |
EP1027454B1 (de) | 2003-08-13 |
ES2205437T3 (es) | 2004-05-01 |
CA2278556C (en) | 2003-07-29 |
DE69817211T2 (de) | 2004-06-03 |
IL130949A0 (en) | 2001-01-28 |
JP3795534B2 (ja) | 2006-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |