ATE247173T1 - Charakterisierung von polypeptiden - Google Patents

Charakterisierung von polypeptiden

Info

Publication number
ATE247173T1
ATE247173T1 AT98900949T AT98900949T ATE247173T1 AT E247173 T1 ATE247173 T1 AT E247173T1 AT 98900949 T AT98900949 T AT 98900949T AT 98900949 T AT98900949 T AT 98900949T AT E247173 T1 ATE247173 T1 AT E247173T1
Authority
AT
Austria
Prior art keywords
terminus
pct
cleavage site
sequence
population
Prior art date
Application number
AT98900949T
Other languages
English (en)
Inventor
Guenter Schmidt
Andrew Hugin Thompson
Original Assignee
Xzillion Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9701357.7A external-priority patent/GB9701357D0/en
Priority claimed from GBGB9726947.6A external-priority patent/GB9726947D0/en
Application filed by Xzillion Gmbh & Co Kg filed Critical Xzillion Gmbh & Co Kg
Application granted granted Critical
Publication of ATE247173T1 publication Critical patent/ATE247173T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT98900949T 1997-01-23 1998-01-23 Charakterisierung von polypeptiden ATE247173T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9701357.7A GB9701357D0 (en) 1997-01-23 1997-01-23 Characterising polypeptides
GBGB9726947.6A GB9726947D0 (en) 1997-12-19 1997-12-19 Characterising polypeptides
PCT/GB1998/000201 WO1998032876A1 (en) 1997-01-23 1998-01-23 Characterising polypeptides

Publications (1)

Publication Number Publication Date
ATE247173T1 true ATE247173T1 (de) 2003-08-15

Family

ID=26310845

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98900949T ATE247173T1 (de) 1997-01-23 1998-01-23 Charakterisierung von polypeptiden

Country Status (12)

Country Link
US (1) US6156527A (de)
EP (1) EP1027454B1 (de)
JP (1) JP3795534B2 (de)
CN (1) CN1118580C (de)
AT (1) ATE247173T1 (de)
AU (1) AU721390B2 (de)
CA (1) CA2278556C (de)
DE (1) DE69817211T2 (de)
ES (1) ES2205437T3 (de)
IL (1) IL130949A (de)
NZ (1) NZ336768A (de)
WO (1) WO1998032876A1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207370B1 (en) 1997-09-02 2001-03-27 Sequenom, Inc. Diagnostics based on mass spectrometric detection of translated target polypeptides
DE69912444T3 (de) 1998-08-25 2010-05-06 University Of Washington, Seattle Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
GB9821393D0 (en) 1998-10-01 1998-11-25 Brax Genomics Ltd Protein profiling 2
ATE344456T1 (de) * 2000-05-05 2006-11-15 Purdue Research Foundation Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen
JP2004503780A (ja) 2000-06-12 2004-02-05 ユニバーシティ　オブ　ワシントン リンペプチドの選択的標識および単離ならびにプロテオーム分析への適用
WO2002014867A2 (en) * 2000-08-11 2002-02-21 Agilix Corporation Ultra-sensitive detection systems
US7973936B2 (en) 2001-01-30 2011-07-05 Board Of Trustees Of Michigan State University Control system and apparatus for use with ultra-fast laser
US7567596B2 (en) 2001-01-30 2009-07-28 Board Of Trustees Of Michigan State University Control system and apparatus for use with ultra-fast laser
US7450618B2 (en) * 2001-01-30 2008-11-11 Board Of Trustees Operating Michigan State University Laser system using ultrashort laser pulses
AU2002245345A1 (en) 2001-01-30 2002-08-12 Board Of Trustees Operating Michigan State University Control system and apparatus for use with laser excitation or ionization
US7609731B2 (en) * 2001-01-30 2009-10-27 Board Of Trustees Operating Michigan State University Laser system using ultra-short laser pulses
US7583710B2 (en) 2001-01-30 2009-09-01 Board Of Trustees Operating Michigan State University Laser and environmental monitoring system
US20020106700A1 (en) * 2001-02-05 2002-08-08 Foote Robert S. Method for analyzing proteins
EP1267170A1 (de) * 2001-06-07 2002-12-18 Xzillion GmbH & CO.KG Verfahren zur Charakterisierung von Polypeptiden
US7163803B2 (en) * 2001-06-07 2007-01-16 Electrophoretics Limited Method for characterizing polypeptides
US6800449B1 (en) * 2001-07-13 2004-10-05 Syngenta Participations Ag High throughput functional proteomics
CA2461587C (en) 2001-09-27 2011-04-26 Purdue Research Foundation Materials and methods for controlling isotope effects during fractionation of analytes
JP2005514603A (ja) * 2001-11-06 2005-05-19 アジリックス・コーポレイション 高感度コード化検出システム
AU2003224253A1 (en) 2002-04-04 2003-10-27 Electrophoretics Limited Method for characterising analytes
US7094345B2 (en) * 2002-09-09 2006-08-22 Cytonome, Inc. Implementation of microfluidic components, including molecular fractionation devices, in a microfluidic system
JP4613299B2 (ja) * 2003-01-30 2011-01-12 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 分析物分析に関する方法、混合物、キット、および組成物
US20050164324A1 (en) * 2003-06-04 2005-07-28 Gygi Steven P. Systems, methods and kits for characterizing phosphoproteomes
WO2005042559A2 (en) * 2003-06-06 2005-05-12 President And Fellows Of Harvard College Capture and release based isotope tagged peptides and methods for using the same
US7579165B2 (en) * 2003-10-16 2009-08-25 Shimadzu Corporation Methods for derivatizing protein or peptide with sulfonic acid groups
JP4576972B2 (ja) * 2003-10-16 2010-11-10 株式会社島津製作所 タンパク質又はペプチドのスルホン酸誘導体化されたｎ末端ペプチドフラグメントを質量分析する方法
US20050147985A1 (en) * 2004-01-05 2005-07-07 Applera Corporation Mixtures of isobarically labeled analytes and fragments ions derived therefrom
US7355045B2 (en) * 2004-01-05 2008-04-08 Applera Corporation Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
US20050148087A1 (en) * 2004-01-05 2005-07-07 Applera Corporation Isobarically labeled analytes and fragment ions derived therefrom
US7307169B2 (en) 2004-01-05 2007-12-11 Applera Corporation Isotopically enriched N-substituted piperazines and methods for the preparation thereof
JP2006078192A (ja) * 2004-09-07 2006-03-23 Shimadzu Corp 生体高分子の質量分析法
US20070207555A1 (en) * 2005-02-03 2007-09-06 Cesar Guerra Ultra-sensitive detection systems using multidimension signals
EP1851532A1 (de) 2005-02-14 2007-11-07 Board of Trustees of Michigan State University Ultraschnelles lasersystem
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
US8618470B2 (en) 2005-11-30 2013-12-31 Board Of Trustees Of Michigan State University Laser based identification of molecular characteristics
US9018562B2 (en) 2006-04-10 2015-04-28 Board Of Trustees Of Michigan State University Laser material processing system
US20090002703A1 (en) * 2006-08-16 2009-01-01 Craig Edward Parman Methods and systems for quantifying isobaric labels and peptides
CN101517416A (zh) * 2006-09-14 2009-08-26 皇家飞利浦电子股份有限公司 基于鉴定羧基端肽分析蛋白质样品的方法
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
US8861075B2 (en) 2009-03-05 2014-10-14 Board Of Trustees Of Michigan State University Laser amplification system
EP2336783A1 (de) * 2009-12-18 2011-06-22 Basf Se C-terminale Sequenzierung von Aminosäuren
US8630322B2 (en) 2010-03-01 2014-01-14 Board Of Trustees Of Michigan State University Laser system for output manipulation
US11435358B2 (en) 2011-06-23 2022-09-06 Board Of Regents, The University Of Texas System Single molecule peptide sequencing
GB2510488B (en) 2011-06-23 2020-04-08 Univ Texas Identifying peptides at the single molecule level
WO2016069124A1 (en) 2014-09-15 2016-05-06 Board Of Regents, The University Of Texas System Improved single molecule peptide sequencing
WO2013112745A1 (en) * 2012-01-24 2013-08-01 The Regents Of The University Of Colorado, A Body Corporate Peptide identification and sequencing by single-molecule detection of peptides undergoing degradation
CN106153712B (zh) * 2015-04-16 2019-02-12 深圳华大生命科学研究院 一种多肽二硫键的定位方法
AU2019301750A1 (en) 2018-07-12 2021-01-28 Board Of Regents, The University Of Texas System Molecular neighborhood detection by oligonucleotides
EP3837271A4 (de) * 2018-08-14 2022-06-15 Board of Regents, The University of Texas System An den haupthistokompatibilitätskomplex gebundene einzelmolekülsequenzierungspeptide
GB2593091B (en) 2018-10-05 2023-12-20 Univ Texas Solid-phase N-terminal peptide capture and release
CN121148475B (zh) * 2025-09-15 2026-04-07 中国科学院生物物理研究所 aa-score驱动的单一位点多肽聚类策略在肽组学研究中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4532207A (en) * 1982-03-19 1985-07-30 G. D. Searle & Co. Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase
SE8803986D0 (sv) * 1988-11-03 1988-11-03 Pharmacia Ab Method for sequencing peptides or proteins
JPH0824576B2 (ja) * 1992-07-22 1996-03-13 農林水産省食品総合研究所長 新規アスパラギニルエンドプロテアーゼとその製造法並びに利用法
US5470703A (en) * 1992-10-21 1995-11-28 Shimadzu Corporation Method for peptide C-terminal fragment sequence analysis and apparatus for collecting peptide fragment

Also Published As

Publication number Publication date
ES2205437T3 (es) 2004-05-01
EP1027454B1 (de) 2003-08-13
IL130949A0 (en) 2001-01-28
AU5674598A (en) 1998-08-18
DE69817211T2 (de) 2004-06-03
CN1118580C (zh) 2003-08-20
JP3795534B2 (ja) 2006-07-12
JP2001508872A (ja) 2001-07-03
IL130949A (en) 2004-12-15
DE69817211D1 (de) 2003-09-18
AU721390B2 (en) 2000-06-29
CA2278556A1 (en) 1998-07-30
US6156527A (en) 2000-12-05
NZ336768A (en) 2001-12-21
WO1998032876A1 (en) 1998-07-30
CA2278556C (en) 2003-07-29
EP1027454A1 (de) 2000-08-16
CN1244218A (zh) 2000-02-09

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