ATE246696T1 - Verfahren zur herstellung von linkern zwischen markierungsgruppen und bio-organischen molekülen auf der basis von platin für die markierung von bio-organischen molekülen zur entdeckung interessanter biologischer substanzen - Google Patents
Verfahren zur herstellung von linkern zwischen markierungsgruppen und bio-organischen molekülen auf der basis von platin für die markierung von bio-organischen molekülen zur entdeckung interessanter biologischer substanzenInfo
- Publication number
- ATE246696T1 ATE246696T1 AT96915218T AT96915218T ATE246696T1 AT E246696 T1 ATE246696 T1 AT E246696T1 AT 96915218 T AT96915218 T AT 96915218T AT 96915218 T AT96915218 T AT 96915218T AT E246696 T1 ATE246696 T1 AT E246696T1
- Authority
- AT
- Austria
- Prior art keywords
- bio
- organic molecules
- platinum
- producing
- discovery
- Prior art date
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title abstract 4
- 239000000126 substance Substances 0.000 title abstract 4
- 238000002372 labelling Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 229910052697 platinum Inorganic materials 0.000 title abstract 2
- 229940045985 antineoplastic platinum compound Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003058 platinum compounds Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95201197 | 1995-05-09 | ||
| PCT/NL1996/000198 WO1996035696A1 (en) | 1995-05-09 | 1996-05-08 | Methods for the production of platinum-based linkers between labels and bio-organic molecules, for labelling bio-organic molecules, for detecting biological substances of interest and diagnostic test kits |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE246696T1 true ATE246696T1 (de) | 2003-08-15 |
Family
ID=8220276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96915218T ATE246696T1 (de) | 1995-05-09 | 1996-05-08 | Verfahren zur herstellung von linkern zwischen markierungsgruppen und bio-organischen molekülen auf der basis von platin für die markierung von bio-organischen molekülen zur entdeckung interessanter biologischer substanzen |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1019420B1 (de) |
| JP (1) | JPH11505533A (de) |
| AT (1) | ATE246696T1 (de) |
| AU (1) | AU724320B2 (de) |
| CA (1) | CA2218815C (de) |
| DE (1) | DE69629403T2 (de) |
| DK (1) | DK1019420T3 (de) |
| ES (1) | ES2205030T3 (de) |
| MX (1) | MX9708590A (de) |
| NZ (1) | NZ307633A (de) |
| PT (1) | PT1019420E (de) |
| WO (1) | WO1996035696A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT937090E (pt) * | 1996-10-08 | 2002-12-31 | Kreatech Biotech Bv | Metodos para a marcacao de nucleotidos, nucleotidos marcados e intermediarios uteis |
| CA2286282A1 (en) * | 1997-04-07 | 1998-10-15 | Institut National De La Sante Et De La Recherche Medicale | Diagnostic means useful for predictive assessment of human hepatocellular carcinoma disease (hcc), as well as diagnostic methods using the same |
| WO1998045304A1 (en) * | 1997-04-10 | 1998-10-15 | Kreatech Biotechnology B.V. | Trans-platinum compound, and diagnostic kit |
| EP0870770A1 (de) * | 1997-04-10 | 1998-10-14 | Kreatech Biotechnology B.V. | Trans-Platinverbindung, ein diese enthaltender, diagnostischer Kit, und ein Verfahren zur Markierung von bioorganischen Molekülen |
| EP1006199A1 (de) | 1998-12-03 | 2000-06-07 | Kreatech Biotechnology B.V. | Verfahren zur Herstellung von Verknüpfungen an ausgewählten Positionen von Nukleinsäuresträngen und deren Verwendung |
| GB0016836D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (1) |
| EP1221465A1 (de) * | 2001-01-03 | 2002-07-10 | Innosense S.r.l. | Symmetrische, monofunktionalisierte Polymethinfarbstoffe als Markierungsreagenzien |
| EP1373572B1 (de) | 2001-03-02 | 2006-07-26 | Stratagene California | Zusammensetzungen und verfahren mit platinverbindungen zur nukleinsäuremarkierung |
| DK1262778T3 (da) | 2001-05-28 | 2008-02-18 | Kreatech Biotech Bv | Fremgangsmåde til differentieret mærkning ved anvendelse af platinkomplekser |
| US7138520B2 (en) | 2003-01-13 | 2006-11-21 | Massachusetts Institute Of Technology | Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same |
| WO2005080331A1 (ja) * | 2004-02-23 | 2005-09-01 | Tetsuo Nagano | 蛍光プローブ |
| EP1745802A1 (de) | 2005-07-20 | 2007-01-24 | Kreatech Biotechnology B.V. | Verfahren zur Konjugierung therapeutischer Verbindungen an zellgezielten Gruppen über Metallkomplexen |
| EP2944647A1 (de) | 2007-07-26 | 2015-11-18 | Cellay, Inc. | Hochsichtbare chromosomenspezifische sonden und zugehörige verfahren |
| WO2011153354A1 (en) | 2010-06-03 | 2011-12-08 | Cellay, Inc. | Methods and kits for in situ detection of nucleotide sequences |
| WO2013048243A1 (en) | 2011-09-29 | 2013-04-04 | Apo-T B.V. | Multi-specific binding molecules targeting aberrant cells |
| JP2015505241A (ja) | 2011-12-12 | 2015-02-19 | セレー，インコーポレイテッド | 生物学的試料中の標的核酸の室温インサイチュ検出のための方法およびキット |
| US10668162B2 (en) | 2012-01-06 | 2020-06-02 | Linxis B.V. | Method for preparing cell targeting conjugates, and the complexes obtained |
| JP2015504895A (ja) * | 2012-01-13 | 2015-02-16 | エーピーオー‐ティー ビー．ヴイ． | 毒性部分を備える異常細胞拘束性免疫グロブリン |
| WO2014070460A1 (en) | 2012-10-31 | 2014-05-08 | Cellay, Inc. | Methods and kits for performing in situ hybridization |
| AU2014346735A1 (en) | 2013-11-07 | 2016-06-09 | Cellay, Inc. | Methods and kits for detecting a prostate carcinoma and predicting disease outcomes for prostate cancers |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4207416A (en) * | 1974-09-05 | 1980-06-10 | Engelhard Minerals & Chemicals Corporation | Ethylenediamineplatinum(II) 2,4-dioxopyrimidine complexes |
| JPS56103192A (en) * | 1980-01-18 | 1981-08-18 | Yoshinori Kitani | Novel platinum complex |
| JPS6087295A (ja) * | 1983-10-19 | 1985-05-16 | Nippon Kayaku Co Ltd | 新規白金錯体 |
| JPS63203692A (ja) * | 1987-02-19 | 1988-08-23 | Nippon Kayaku Co Ltd | 新規白金錯体 |
| EP0386243A4 (en) * | 1987-11-06 | 1990-10-10 | Sagami Chemical Research Center | Platinum (ii) complexes |
| US4946954A (en) * | 1989-01-17 | 1990-08-07 | Georgetown University | Platinum pharmaceutical agents |
| NL9001639A (nl) * | 1990-07-19 | 1992-02-17 | Amc Amsterdam | Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen. |
-
1996
- 1996-05-08 EP EP96915218A patent/EP1019420B1/de not_active Expired - Lifetime
- 1996-05-08 NZ NZ307633A patent/NZ307633A/xx not_active IP Right Cessation
- 1996-05-08 PT PT96915218T patent/PT1019420E/pt unknown
- 1996-05-08 JP JP8533965A patent/JPH11505533A/ja active Pending
- 1996-05-08 WO PCT/NL1996/000198 patent/WO1996035696A1/en active IP Right Grant
- 1996-05-08 DK DK96915218T patent/DK1019420T3/da active
- 1996-05-08 AT AT96915218T patent/ATE246696T1/de active
- 1996-05-08 CA CA002218815A patent/CA2218815C/en not_active Expired - Lifetime
- 1996-05-08 DE DE69629403T patent/DE69629403T2/de not_active Expired - Lifetime
- 1996-05-08 ES ES96915218T patent/ES2205030T3/es not_active Expired - Lifetime
- 1996-05-08 AU AU57040/96A patent/AU724320B2/en not_active Ceased
-
1997
- 1997-11-07 MX MX9708590A patent/MX9708590A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996035696A1 (en) | 1996-11-14 |
| DE69629403D1 (de) | 2003-09-11 |
| CA2218815A1 (en) | 1996-11-14 |
| DK1019420T3 (da) | 2003-11-24 |
| CA2218815C (en) | 2008-05-20 |
| EP1019420B1 (de) | 2003-08-06 |
| AU724320B2 (en) | 2000-09-14 |
| NZ307633A (en) | 2000-01-28 |
| PT1019420E (pt) | 2003-12-31 |
| AU5704096A (en) | 1996-11-29 |
| DE69629403T2 (de) | 2004-06-24 |
| ES2205030T3 (es) | 2004-05-01 |
| EP1019420A1 (de) | 2000-07-19 |
| JPH11505533A (ja) | 1999-05-21 |
| MX9708590A (es) | 1998-06-30 |
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| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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