PT937090E - Metodos para a marcacao de nucleotidos, nucleotidos marcados e intermediarios uteis - Google Patents

Metodos para a marcacao de nucleotidos, nucleotidos marcados e intermediarios uteis

Info

Publication number
PT937090E
PT937090E PT97943223T PT97943223T PT937090E PT 937090 E PT937090 E PT 937090E PT 97943223 T PT97943223 T PT 97943223T PT 97943223 T PT97943223 T PT 97943223T PT 937090 E PT937090 E PT 937090E
Authority
PT
Portugal
Prior art keywords
nucleotides
chain
spacer
moiety
linker
Prior art date
Application number
PT97943223T
Other languages
English (en)
Inventor
Hendrik Jan Houthoff
Jan Reedijk
Tinka Jelsma
Robert Jochem Heetebrij
Herman Hendricus Volkers
Original Assignee
Kreatech Biotech Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kreatech Biotech Bv filed Critical Kreatech Biotech Bv
Publication of PT937090E publication Critical patent/PT937090E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cold Cathode And The Manufacture (AREA)
  • Inorganic Insulating Materials (AREA)
  • Medicinal Preparation (AREA)
PT97943223T 1996-10-08 1997-10-08 Metodos para a marcacao de nucleotidos, nucleotidos marcados e intermediarios uteis PT937090E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96202792 1996-10-08

Publications (1)

Publication Number Publication Date
PT937090E true PT937090E (pt) 2002-12-31

Family

ID=8224469

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97943223T PT937090E (pt) 1996-10-08 1997-10-08 Metodos para a marcacao de nucleotidos, nucleotidos marcados e intermediarios uteis

Country Status (12)

Country Link
US (4) US6338943B1 (pt)
EP (1) EP0937090B1 (pt)
JP (2) JP4981197B2 (pt)
AT (1) ATE221894T1 (pt)
AU (1) AU726692B2 (pt)
CA (1) CA2267133C (pt)
DE (1) DE69714600T2 (pt)
DK (1) DK0937090T3 (pt)
ES (1) ES2182121T3 (pt)
NZ (1) NZ334803A (pt)
PT (1) PT937090E (pt)
WO (1) WO1998015564A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0937090T3 (da) * 1996-10-08 2002-12-02 Kreatech Biotech Bv Fremgangsmåder til mærkning af nucleotider, mærkede nucleotider og nyttige mellemprodukter
US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
EP1006199A1 (en) 1998-12-03 2000-06-07 Kreatech Biotechnology B.V. Applications with and methods for producing selected interstrand crosslinks in nucleic acid
EP1218547A4 (en) * 1999-10-15 2005-04-20 Ventana Med Syst Inc METHOD OF IN-SITU DETECTION OF INDIVIDUAL GENOCOPIES
US6376669B1 (en) * 1999-11-05 2002-04-23 3M Innovative Properties Company Dye labeled imidazoquinoline compounds
GB0016836D0 (en) 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
DE60213387D1 (de) 2001-03-02 2006-09-07 Stratagene California Zusammensetzungen und verfahren mit platinverbindungen zur nukleinsäuremarkierung
DE60131070T2 (de) * 2001-05-28 2008-08-07 Kreatech Biotechnology B.V. Ein Verfahren zur differentiellen Markierung mittels Platin-Komplexen
US7166478B2 (en) * 2002-03-12 2007-01-23 Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses
WO2004027384A2 (en) * 2002-09-17 2004-04-01 Perkinelmer Life Sciences, Inc. Real-time detection of nucleic acid reactions
US20050028450A1 (en) * 2003-08-07 2005-02-10 Wen-Qing Xu CMP slurry
US20060281100A1 (en) * 2005-06-14 2006-12-14 Shen Gene G Thiotriphosphate nucleotide dye terminators
EP1745802A1 (en) 2005-07-20 2007-01-24 Kreatech Biotechnology B.V. Method of conjugating therapeutic compounds to cell targeting moieties via metal complexes
US20090148958A1 (en) * 2006-04-27 2009-06-11 Onecell Inc. Nucleotide-transition metal complex catalyst
EP2944647A1 (en) 2007-07-26 2015-11-18 Cellay, Inc. Highly visible chromosome-specific probes and related methods
KR101072900B1 (ko) * 2007-12-04 2011-10-17 주식회사 파나진 고정화된 펩티드핵산 프로브를 사용한 표적핵산의 선택적 표지 및 검출 방법
EP2800587A2 (en) 2012-01-06 2014-11-12 LinXis B.V. Method for preparing cell targeting conjugates, and the complexes obtained
CN109030698B (zh) * 2018-08-06 2020-09-04 泰山医学院 一种液相色谱法检测固体福美钠纯度的方法
CN108760961B (zh) * 2018-08-06 2020-09-22 青岛中科荣达新材料有限公司 一种液相色谱法检测固体福美钾纯度的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207416A (en) * 1974-09-05 1980-06-10 Engelhard Minerals & Chemicals Corporation Ethylenediamineplatinum(II) 2,4-dioxopyrimidine complexes
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
DE3568063D1 (en) * 1985-01-10 1989-03-09 Molecular Diagnostics Inc Photochemical method of labelling nucleic acids for detection in hybridization assays
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
EP0386243A4 (en) * 1987-11-06 1990-10-10 Sagami Chemical Research Center Platinum (ii) complexes
US5552541A (en) * 1990-06-20 1996-09-03 Beckman Instruments, Inc. Haptenic probes for detecting capture polynucleotides
US5714327A (en) * 1990-07-19 1998-02-03 Kreatech Diagnostics Platinum-containing compounds, methods for their preparation and applications thereof
NL9001639A (nl) * 1990-07-19 1992-02-17 Amc Amsterdam Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen.
EP0646019B9 (en) * 1992-06-09 2002-12-18 Neorx Corporation Biotin-DOTA conjugates and their use in pretargeting methods
JPH0698797A (ja) * 1992-09-22 1994-04-12 Toyobo Co Ltd 核酸検出法
DE4344742A1 (de) * 1993-06-09 1994-12-15 Boehringer Mannheim Gmbh Verfahren zur Immobilisierung von Nukleinsäuren
DE4326466A1 (de) * 1993-08-06 1995-02-09 Boehringer Mannheim Gmbh Infrarot-Farbstoff-markierte Nucleotide und ihre Verwendung in der Nucleinsäure-Detektion
PT1019420E (pt) * 1995-05-09 2003-12-31 Kreatech Biotech Bv Metodos para a producao de ligandos baseados em platina para ligacao entre marcadores e moleculas bio-orgaicas na marcacao de moleculas bio-organicas com o fim de detectar substancias biologicas de interesse e conjuntos ("kits") de ensaios de diagnosticos
DK0937090T3 (da) * 1996-10-08 2002-12-02 Kreatech Biotech Bv Fremgangsmåder til mærkning af nucleotider, mærkede nucleotider og nyttige mellemprodukter

Also Published As

Publication number Publication date
CA2267133C (en) 2006-07-18
AU726692B2 (en) 2000-11-16
DE69714600D1 (de) 2002-09-12
US20050118621A1 (en) 2005-06-02
US7217813B2 (en) 2007-05-15
EP0937090B1 (en) 2002-08-07
JP2001503742A (ja) 2001-03-21
WO1998015564A1 (en) 1998-04-16
DK0937090T3 (da) 2002-12-02
AU4474697A (en) 1998-05-05
US6338943B1 (en) 2002-01-15
CA2267133A1 (en) 1998-04-16
NZ334803A (en) 2000-05-26
ES2182121T3 (es) 2003-03-01
DE69714600T2 (de) 2003-03-27
JP2010166914A (ja) 2010-08-05
JP4981197B2 (ja) 2012-07-18
EP0937090A1 (en) 1999-08-25
US20020160396A1 (en) 2002-10-31
US6797818B2 (en) 2004-09-28
ATE221894T1 (de) 2002-08-15
USRE40557E1 (en) 2008-10-28

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