ATE244279T1 - Verfahren zur synthese von phthalocyaninverbindungen - Google Patents
Verfahren zur synthese von phthalocyaninverbindungenInfo
- Publication number
- ATE244279T1 ATE244279T1 AT97945416T AT97945416T ATE244279T1 AT E244279 T1 ATE244279 T1 AT E244279T1 AT 97945416 T AT97945416 T AT 97945416T AT 97945416 T AT97945416 T AT 97945416T AT E244279 T1 ATE244279 T1 AT E244279T1
- Authority
- AT
- Austria
- Prior art keywords
- ligand
- displacing
- phthalocyanine
- cl3ccoo
- central silicon
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 7
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical class N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 title abstract 6
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 abstract 13
- -1 phthalocyanine compound Chemical class 0.000 abstract 5
- 239000002243 precursor Substances 0.000 abstract 5
- 229910052710 silicon Inorganic materials 0.000 abstract 5
- 239000010703 silicon Substances 0.000 abstract 5
- 230000002194 synthesizing effect Effects 0.000 abstract 3
- 125000002346 iodo group Chemical group I* 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 238000006303 photolysis reaction Methods 0.000 abstract 1
- 230000015843 photosynthesis, light reaction Effects 0.000 abstract 1
- 125000004469 siloxy group Chemical group [SiH3]O* 0.000 abstract 1
- JACPFCQFVIAGDN-UHFFFAOYSA-M sipc iv Chemical compound [OH-].[Si+4].CN(C)CCC[Si](C)(C)[O-].C=1C=CC=C(C(N=C2[N-]C(C3=CC=CC=C32)=N2)=N3)C=1C3=CC([C]1C=CC=CC1=1)=NC=1N=C1[C]3C=CC=CC3=C2[N-]1 JACPFCQFVIAGDN-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B47/00—Porphines; Azaporphines
- C09B47/04—Phthalocyanines abbreviation: Pc
- C09B47/30—Metal-free phthalocyanines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B47/00—Porphines; Azaporphines
- C09B47/04—Phthalocyanines abbreviation: Pc
- C09B47/08—Preparation from other phthalocyanine compounds, e.g. cobaltphthalocyanineamine complex
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/724,347 US5763602A (en) | 1996-10-01 | 1996-10-01 | Methods of syntheses of phthalocyanine compounds |
| PCT/US1997/017690 WO1998014521A1 (en) | 1996-10-01 | 1997-09-30 | Novel methods of syntheses of phthalocyanine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE244279T1 true ATE244279T1 (de) | 2003-07-15 |
Family
ID=24910068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97945416T ATE244279T1 (de) | 1996-10-01 | 1997-09-30 | Verfahren zur synthese von phthalocyaninverbindungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5763602A (de) |
| EP (1) | EP1023399B1 (de) |
| JP (1) | JP2001506584A (de) |
| KR (1) | KR20000036186A (de) |
| AT (1) | ATE244279T1 (de) |
| AU (1) | AU4662697A (de) |
| CA (1) | CA2267389A1 (de) |
| DE (1) | DE69723322T2 (de) |
| WO (1) | WO1998014521A1 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6322980B1 (en) * | 1999-04-30 | 2001-11-27 | Aclara Biosciences, Inc. | Single nucleotide detection using degradation of a fluorescent sequence |
| US7771929B2 (en) * | 2000-04-28 | 2010-08-10 | Monogram Biosciences, Inc. | Tag library compounds, compositions, kits and methods of use |
| US20030207300A1 (en) * | 2000-04-28 | 2003-11-06 | Matray Tracy J. | Multiplex analytical platform using molecular tags |
| US7537938B2 (en) * | 2000-04-28 | 2009-05-26 | Monogram Biosciences, Inc. | Biomarker detection in circulating cells |
| US7160735B2 (en) * | 2000-04-28 | 2007-01-09 | Monogram Biosciences, Inc. | Tagged microparticle compositions and methods |
| AU2002305658A1 (en) | 2001-05-21 | 2002-12-03 | Aclara Biosciences, Inc. | Analyzing phosphorylated proteins |
| JP2005505749A (ja) | 2001-05-21 | 2005-02-24 | アクララ バイオサイエンシーズ， インコーポレイテッド | タンパク質を分析するための方法および組成物 |
| WO2002096913A1 (en) * | 2001-05-25 | 2002-12-05 | Gentian As | Substituted di(hydroxy/alkoxy)silicon phthalocyanines and their uses |
| US7358052B2 (en) * | 2001-05-26 | 2008-04-15 | Monogram Biosciences, Inc. | Catalytic amplification of multiplexed assay signals |
| US20040229380A1 (en) * | 2002-05-21 | 2004-11-18 | Po-Ying Chan-Hui | ErbB heterodimers as biomarkers |
| US7105308B2 (en) | 2002-07-25 | 2006-09-12 | Monogram Biosciences, Inc. | Detecting receptor oligomerization |
| US20040091850A1 (en) * | 2002-11-08 | 2004-05-13 | Travis Boone | Single cell analysis of membrane molecules |
| US7402398B2 (en) * | 2003-07-17 | 2008-07-22 | Monogram Biosciences, Inc. | Measuring receptor homodimerization |
| CA2535510C (en) * | 2003-08-11 | 2013-10-15 | Monogram Biosciences, Inc. | Detecting and profiling molecular complexes |
| CA2543830A1 (en) * | 2003-10-27 | 2005-05-19 | Monogram Biosciences, Inc. | Detecting human anti-therapeutic antibodies |
| US7939267B2 (en) * | 2004-11-04 | 2011-05-10 | Laboratory Corporation Of America Holdings | Detection of activation of endothelial cells as surrogate marker for angiogenesis |
| WO2008098100A2 (en) * | 2007-02-07 | 2008-08-14 | Perscitus Biosciences, Llc | Detection of molecule proximity |
| CA2711843C (en) * | 2007-12-20 | 2018-11-13 | Laboratory Corporation Of America Holdings | Her-2 diagnostic methods |
| US8470542B2 (en) * | 2008-12-01 | 2013-06-25 | Laboratory Corporation Of America Holdings | Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95 |
| SG172983A1 (en) | 2009-01-15 | 2011-08-29 | Lab Corp America Holdings | Methods of determining patient response by measurement of her-3 |
| CA2753269C (en) | 2009-02-20 | 2017-04-25 | Perkinelmer Biosignal, Inc. | Multiplex assay methods and compositions |
| US8440641B2 (en) * | 2009-03-20 | 2013-05-14 | Case Western Reserve University | Phthalocyanine salt formulations |
| JP6468838B2 (ja) | 2011-05-19 | 2019-02-13 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | 癌患者の生存可能性を決定するためおよび癌患者における転移可能性を予測するための方法 |
| WO2013020067A1 (en) | 2011-08-03 | 2013-02-07 | Sun Chemical Corporation | Phthalocyanine synthesis |
| KR101471613B1 (ko) * | 2013-02-07 | 2014-12-12 | 광주과학기술원 | 고분자 태양전지 및 이의 제조방법 |
| CN105264382A (zh) | 2013-04-05 | 2016-01-20 | 美国控股实验室公司 | 基于检测her3活化辅助癌症的诊断、预后和治疗的系统和方法 |
| JP2019515252A (ja) | 2016-03-15 | 2019-06-06 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | 細胞間のタンパク質相互作用を評価する方法 |
| PT3482210T (pt) | 2016-07-06 | 2021-07-28 | Prothena Biosciences Ltd | Ensaio para detetar alfa-sinucleína total e fosforilada s129 |
| CA3046489A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| KR102616436B1 (ko) | 2016-12-14 | 2023-12-27 | 비오라 쎄라퓨틱스, 인크. | Tnf 저해제로의 위장관 질환의 치료 |
| EP3554344A1 (de) | 2016-12-14 | 2019-10-23 | Progenity, Inc. | Behandlung der erkrankung des gastrointestinaltraktes mit einem tlr-modulator |
| WO2018112232A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device |
| TW201834690A (zh) | 2016-12-14 | 2018-10-01 | 美商寶珍那提公司 | 以免疫抑制劑治療胃腸道疾病 |
| WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
| EP3554541B1 (de) | 2016-12-14 | 2023-06-07 | Biora Therapeutics, Inc. | Behandlung einer erkrankung des gastrointestinaltraktes mit einem chemokin/chemokin-rezeptor-inhibitor |
| EP3554345A1 (de) | 2016-12-14 | 2019-10-23 | Progenity, Inc. | Behandlung von erkrankungen des gastrointestinaltraktes mit einem smad7-inhibitor |
| AU2017378398B2 (en) | 2016-12-14 | 2023-02-02 | Bt Bidco, Inc. | Treatment of a disease of the gastrointestinal tract with a JAK inhibitor and devices |
| CA3045931A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| EP3554343A1 (de) | 2016-12-14 | 2019-10-23 | Progenity, Inc. | Behandlung einer erkrankung des gastrointestinaltraktes mit einem il-1-inhibitor |
| CA3054156A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist |
| WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
| CA3054159A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor |
| US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| AU2018244922A1 (en) | 2017-03-30 | 2019-09-12 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with live biotherapeutics |
| US20200306516A1 (en) | 2017-08-14 | 2020-10-01 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with glatiramer or a pharmaceutically acceptable salt thereof |
| CA3102255A1 (en) | 2018-06-01 | 2019-12-05 | Progenity, Inc. | Devices and systems for gastrointestinal microbiome detection and manipulation |
| WO2021207691A1 (en) * | 2020-04-10 | 2021-10-14 | Rakuten Medical, Inc. | Phthalocyanine dye compounds, conjugates and methods of use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4927735A (en) * | 1987-01-07 | 1990-05-22 | Hitachi Chemical Company, Ltd. | Novel naphthalocyanine dye, method for preparing the same, and optical information recording medium employing the same |
| ATE206395T1 (de) * | 1990-05-15 | 2001-10-15 | Hyperion Inc | Fluoreszierende porphyrin- und fluoreszierende phthalocyanin-polyethylenglykol-, polyol- und saccharidderivate als fluoreszierende sonden |
| US5166197A (en) * | 1990-07-17 | 1992-11-24 | Kenney Malcolm E | Phthalocyanine photosensitizers for photodynamic therapy |
| US5484778C1 (en) * | 1990-07-17 | 2001-05-08 | Univ Cleveland Hospitals | Phthalocynine photosensitizers for photodynamic therapy and methods for their use |
| TW235298B (de) * | 1992-02-27 | 1994-12-01 | Ciba Geigy |
-
1996
- 1996-10-01 US US08/724,347 patent/US5763602A/en not_active Expired - Lifetime
-
1997
- 1997-09-30 AU AU46626/97A patent/AU4662697A/en not_active Abandoned
- 1997-09-30 WO PCT/US1997/017690 patent/WO1998014521A1/en not_active Ceased
- 1997-09-30 KR KR1019997002241A patent/KR20000036186A/ko not_active Ceased
- 1997-09-30 DE DE69723322T patent/DE69723322T2/de not_active Expired - Fee Related
- 1997-09-30 EP EP97945416A patent/EP1023399B1/de not_active Expired - Lifetime
- 1997-09-30 CA CA002267389A patent/CA2267389A1/en not_active Abandoned
- 1997-09-30 AT AT97945416T patent/ATE244279T1/de not_active IP Right Cessation
- 1997-09-30 JP JP51683598A patent/JP2001506584A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69723322T2 (de) | 2004-05-27 |
| KR20000036186A (ko) | 2000-06-26 |
| AU4662697A (en) | 1998-04-24 |
| EP1023399A4 (de) | 2002-02-27 |
| WO1998014521A1 (en) | 1998-04-09 |
| JP2001506584A (ja) | 2001-05-22 |
| CA2267389A1 (en) | 1998-04-09 |
| DE69723322D1 (de) | 2003-08-07 |
| US5763602A (en) | 1998-06-09 |
| EP1023399B1 (de) | 2003-07-02 |
| EP1023399A1 (de) | 2000-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |