ATE242877T1 - Zusammensetzungen und verfahren für die schnelle analyse von retikulozyten - Google Patents
Zusammensetzungen und verfahren für die schnelle analyse von retikulozytenInfo
- Publication number
- ATE242877T1 ATE242877T1 AT96912970T AT96912970T ATE242877T1 AT E242877 T1 ATE242877 T1 AT E242877T1 AT 96912970 T AT96912970 T AT 96912970T AT 96912970 T AT96912970 T AT 96912970T AT E242877 T1 ATE242877 T1 AT E242877T1
- Authority
- AT
- Austria
- Prior art keywords
- reagent
- group
- reticulocytes
- tris
- bis
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 210000001995 reticulocyte Anatomy 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 5
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 abstract 2
- ZWEVPYNPHSPIFU-AUGHYPCGSA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxy-n-[3-[3-[[(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoyl]amino]propyl-[(4r)-4-[(3r,5s,7r,8r,9s,10s,12s,13r,14s,17r)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenan Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)N(CCCNC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)CCCNC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C)[C@@]2(C)[C@@H](O)C1 ZWEVPYNPHSPIFU-AUGHYPCGSA-N 0.000 abstract 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 239000007983 Tris buffer Substances 0.000 abstract 1
- 150000001447 alkali salts Chemical class 0.000 abstract 1
- OWMVSZAMULFTJU-UHFFFAOYSA-N bis-tris Chemical compound OCCN(CCO)C(CO)(CO)CO OWMVSZAMULFTJU-UHFFFAOYSA-N 0.000 abstract 1
- 229920001400 block copolymer Polymers 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 235000011148 calcium chloride Nutrition 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 235000011147 magnesium chloride Nutrition 0.000 abstract 1
- 229910001629 magnesium chloride Inorganic materials 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 238000010186 staining Methods 0.000 abstract 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
- 239000011592 zinc chloride Substances 0.000 abstract 1
- 235000005074 zinc chloride Nutrition 0.000 abstract 1
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1477—Multiparameters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/426,408 US5691204A (en) | 1995-04-21 | 1995-04-21 | Compositions and methods for the rapid analysis of reticulocytes |
| PCT/US1996/005520 WO1996033396A1 (en) | 1995-04-21 | 1996-04-19 | Compositions and methods for the rapid analysis of reticulocytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE242877T1 true ATE242877T1 (de) | 2003-06-15 |
Family
ID=23690691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96912970T ATE242877T1 (de) | 1995-04-21 | 1996-04-19 | Zusammensetzungen und verfahren für die schnelle analyse von retikulozyten |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5691204A (de) |
| EP (1) | EP0842410B1 (de) |
| JP (1) | JP3600247B2 (de) |
| AT (1) | ATE242877T1 (de) |
| DE (1) | DE69628651T2 (de) |
| ES (1) | ES2201182T3 (de) |
| WO (1) | WO1996033396A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5733784A (en) * | 1995-11-20 | 1998-03-31 | Abbott Laboratories | Reagent system and method for the differentiation and identification of reticulocytes |
| FR2759166B1 (fr) * | 1997-01-31 | 1999-04-23 | Abx Sa | Reactif de coloration pour la determination de cellules sanguines |
| US6114173A (en) * | 1997-04-03 | 2000-09-05 | Bayer Corporation | Fully automated method and reagent composition therefor for rapid identification and characterization of reticulocytes erythrocytes and platelets in whole blood |
| US5935857A (en) * | 1997-08-01 | 1999-08-10 | Coulter International Corp. | Blood diluent |
| US6060322A (en) * | 1998-10-20 | 2000-05-09 | Coulter International Corp. | Method for identification of reticulated cells |
| US6271035B1 (en) * | 1998-10-20 | 2001-08-07 | Coulter International Corp. | Methods and compositions for rapid staining of nucleic acids in whole cells |
| US6944493B2 (en) * | 1999-09-10 | 2005-09-13 | Akora, Inc. | Indocyanine green (ICG) compositions and related methods of use |
| US6351663B1 (en) | 1999-09-10 | 2002-02-26 | Akorn, Inc. | Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation |
| US6443976B1 (en) | 1999-11-30 | 2002-09-03 | Akorn, Inc. | Methods for treating conditions and illnesses associated with abnormal vasculature |
| US6368864B1 (en) | 2000-05-05 | 2002-04-09 | Coulter International Corp. | Dyes and methods of reticulocyte enumeration |
| US6784981B1 (en) * | 2000-06-02 | 2004-08-31 | Idexx Laboratories, Inc. | Flow cytometry-based hematology system |
| US6630990B2 (en) | 2001-06-05 | 2003-10-07 | Abbott Laboratories | Optical method and apparatus for red blood cell differentiation on a cell-by-cell basis, and simultaneous analysis of white blood cell differentiation |
| US6955872B2 (en) * | 2003-03-20 | 2005-10-18 | Coulter International Corp. | Dye compositions which provide enhanced differential fluorescence and light scatter characteristics |
| US20100012377A1 (en) * | 2005-11-16 | 2010-01-21 | The Charles Machine Works, Inc. | System And Apparatus For Locating And Avoiding An Underground Obstacle |
| PL2244086T3 (pl) * | 2006-04-08 | 2021-11-22 | F. Hoffmann-La Roche Ag | Analiza danych optycznych za pomocą histogramów |
| US20080102526A1 (en) * | 2006-10-30 | 2008-05-01 | Sysmex Corporation | Reagent, reagent kit and analyzing method |
| CN101349644B (zh) | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
| US8102161B2 (en) * | 2007-09-25 | 2012-01-24 | Tdk Corporation | Stable output in a switching power supply by smoothing the output of the secondary coil |
| CN101475754A (zh) | 2008-01-04 | 2009-07-08 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 |
| CN101602762B (zh) | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
| CN101726579B (zh) | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
| US8367358B2 (en) | 2008-12-17 | 2013-02-05 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Reagent, kit and method for differentiating and counting leukocytes |
| CN101988082B (zh) | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
| US9194780B2 (en) | 2010-12-15 | 2015-11-24 | Dna Medicine Institute, Inc. | Microfluidic passive mixing chip |
| ES2895391T3 (es) * | 2011-12-27 | 2022-02-21 | Abbott Lab | Análisis celular de fluidos corporales |
| KR20150009880A (ko) * | 2013-07-17 | 2015-01-27 | 삼성전자주식회사 | 직관형 발광 장치 |
| WO2017158431A1 (en) * | 2016-03-17 | 2017-09-21 | Delta Instruments B.V. | Detection of cells in a liquid sample |
| CN110799679A (zh) * | 2017-06-20 | 2020-02-14 | 10X基因组学有限公司 | 用于改善液滴稳定的方法和系统 |
| US10914913B2 (en) | 2018-03-30 | 2021-02-09 | Idexx Laboratories, Inc. | Flow cytometer, laser optics assembly thereof, and methods of assembling the same |
| CA3182847A1 (en) | 2020-06-17 | 2021-12-23 | Garland Christian Misener | Flow cytometer and laser optics assembly thereof |
| EP4365570A1 (de) * | 2022-11-04 | 2024-05-08 | Horiba, Ltd. | Messverfahren, messsystem und testreagenzienkit |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3684377A (en) * | 1970-07-13 | 1972-08-15 | Bio Physics Systems Inc | Method for analysis of blood by optical analysis of living cells |
| US3883247A (en) * | 1973-10-30 | 1975-05-13 | Bio Physics Systems Inc | Method for fluorescence analysis of white blood cells |
| US4544546A (en) * | 1980-04-21 | 1985-10-01 | Abbott Laboratories | Fluorescent nucleic acid stains |
| US4336029A (en) * | 1980-08-15 | 1982-06-22 | Ortho Diagnostic Systems Inc. | Method and reagents for quantitative determination of reticulocytes and platelets in whole blood |
| US5004804A (en) * | 1984-01-12 | 1991-04-02 | Nordisk Gentofte | Method and composition for preparation of factor VIIIC |
| US4751181A (en) * | 1984-12-31 | 1988-06-14 | Duke University | Methods and compositions useful in the diagnosis and treatment of autoimmune diseases |
| US4978624A (en) * | 1985-09-06 | 1990-12-18 | Technicon Instruments Corporation | Reagent for the determination of a differential white blood cell count |
| US4707451A (en) * | 1985-09-18 | 1987-11-17 | Becton, Dickinson And Company | Detection of reticulocytes |
| EP0226272B1 (de) * | 1985-11-01 | 1991-03-06 | Becton, Dickinson and Company | Nachweis von Retikulozyten |
| US4883867A (en) * | 1985-11-01 | 1989-11-28 | Becton, Dickinson And Company | Detection of reticulocytes, RNA or DNA |
| US5175109A (en) * | 1986-09-10 | 1992-12-29 | Toa Medical Electronics Co., Ltd. | Reagent for classifying leukocytes by flow cytometry |
| US5155044A (en) * | 1987-03-13 | 1992-10-13 | Coulter Electronics, Inc. | Lysing reagent system for isolation, identification and/or analysis of leukocytes from whole blood samples |
| US5389549A (en) * | 1987-05-29 | 1995-02-14 | Toa Medical Electronics Co., Ltd. | Method for classifying leukocytes and a reagent used therefor |
| JPH0746102B2 (ja) * | 1987-07-31 | 1995-05-17 | 東亜医用電子株式会社 | フロ−サイトメトリ用網状赤血球測定試薬 |
| JP2549665B2 (ja) * | 1987-07-31 | 1996-10-30 | 東亜医用電子株式会社 | フロ−サイトメトリ用網状赤血球測定試薬 |
| US5110726A (en) * | 1987-08-27 | 1992-05-05 | Board Of Regents, The University Of Texas System | Immunoassay for antibodies binding platelets |
| US4985176A (en) * | 1987-12-04 | 1991-01-15 | Murata Manufacturing Co., Ltd. | Resistive paste |
| JP2619900B2 (ja) * | 1988-01-27 | 1997-06-11 | 東亜医用電子株式会社 | 血液中の白血球およびヘモグロビンの測定用試薬および方法 |
| US4937198A (en) * | 1989-07-28 | 1990-06-26 | Becton, Dickinson And Company | Novel fluorescent dye |
| JP2941041B2 (ja) * | 1990-11-16 | 1999-08-25 | シスメックス株式会社 | フローサイトメトリーによる白血球の分類方法 |
| JP3067849B2 (ja) * | 1991-07-29 | 2000-07-24 | シスメックス株式会社 | 白血球分類計数用試料調製方法 |
| US5350695A (en) * | 1991-12-05 | 1994-09-27 | Miles Inc. | Methods for the identification and characterization of reticulocytes in whole blood |
| US5360739A (en) * | 1991-12-05 | 1994-11-01 | Miles Inc. | Methods for the identification and characterization of reticulocytes in whole blood |
| US5284771A (en) * | 1991-12-05 | 1994-02-08 | Miles Inc. | Reagent compositions and their use in sphering cells |
| CA2087086A1 (en) * | 1992-01-22 | 1993-07-23 | Leon Wmm Terstappen | Multidimensional cell differential analysis |
| US5451525A (en) * | 1992-02-14 | 1995-09-19 | Coulter Corporation | Method and materials for determining particle count in a flow cytometer |
| WO1993018397A1 (en) * | 1992-03-02 | 1993-09-16 | Streck Laboratories, Inc. | Reference control for use with manual and flow cytometric reticulocyte counting devices |
| EP0598663B1 (de) * | 1992-11-19 | 2000-02-02 | Sysmex Corporation | Verfahren zur Vorbehandlung für Blutanalyse |
| JP3421111B2 (ja) * | 1993-02-22 | 2003-06-30 | シスメックス株式会社 | マラリア感染細胞の検出方法及び試薬 |
| JP3301646B2 (ja) * | 1993-03-19 | 2002-07-15 | シスメックス株式会社 | 幼若細胞測定用試薬 |
| US5534416A (en) * | 1993-04-13 | 1996-07-09 | Molecular Probes, Inc. | Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes |
| US5436134A (en) * | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
| JPH07333220A (ja) * | 1993-05-28 | 1995-12-22 | Omron Corp | 網状赤血球の測定方法及び網状赤血球測定装置 |
| US5563070A (en) * | 1993-05-28 | 1996-10-08 | Omron Corporation | Method of counting reticulocytes |
-
1995
- 1995-04-21 US US08/426,408 patent/US5691204A/en not_active Expired - Lifetime
-
1996
- 1996-04-19 ES ES96912970T patent/ES2201182T3/es not_active Expired - Lifetime
- 1996-04-19 AT AT96912970T patent/ATE242877T1/de not_active IP Right Cessation
- 1996-04-19 JP JP53197596A patent/JP3600247B2/ja not_active Expired - Lifetime
- 1996-04-19 DE DE69628651T patent/DE69628651T2/de not_active Expired - Lifetime
- 1996-04-19 WO PCT/US1996/005520 patent/WO1996033396A1/en active IP Right Grant
- 1996-04-19 EP EP96912970A patent/EP0842410B1/de not_active Expired - Lifetime
- 1996-12-20 US US08/777,727 patent/US5773299A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP3600247B2 (ja) | 2004-12-15 |
| EP0842410A1 (de) | 1998-05-20 |
| US5773299A (en) | 1998-06-30 |
| US5691204A (en) | 1997-11-25 |
| DE69628651T2 (de) | 2004-04-29 |
| ES2201182T3 (es) | 2004-03-16 |
| WO1996033396A1 (en) | 1996-10-24 |
| JPH11508353A (ja) | 1999-07-21 |
| EP0842410B1 (de) | 2003-06-11 |
| DE69628651D1 (de) | 2003-07-17 |
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