ATE237338T1 - Allogene parakrine cytokine tumor impfstoffe - Google Patents
Allogene parakrine cytokine tumor impfstoffeInfo
- Publication number
- ATE237338T1 ATE237338T1 AT96945109T AT96945109T ATE237338T1 AT E237338 T1 ATE237338 T1 AT E237338T1 AT 96945109 T AT96945109 T AT 96945109T AT 96945109 T AT96945109 T AT 96945109T AT E237338 T1 ATE237338 T1 AT E237338T1
- Authority
- AT
- Austria
- Prior art keywords
- cell line
- tumor cell
- allogene
- tumor
- tumor vaccines
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 102000004127 Cytokines Human genes 0.000 title abstract 2
- 108090000695 Cytokines Proteins 0.000 title abstract 2
- 230000003076 paracrine Effects 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 210000004881 tumor cell Anatomy 0.000 abstract 9
- 206010061902 Pancreatic neoplasm Diseases 0.000 abstract 2
- 201000002528 pancreatic cancer Diseases 0.000 abstract 2
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001136—Cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001136—Cytokines
- A61K39/001139—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57970895A | 1995-12-28 | 1995-12-28 | |
| PCT/US1996/020802 WO1997024132A1 (en) | 1995-12-28 | 1996-12-26 | Allogeneic paracrine cytokine tumor vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237338T1 true ATE237338T1 (de) | 2003-05-15 |
Family
ID=24318022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96945109T ATE237338T1 (de) | 1995-12-28 | 1996-12-26 | Allogene parakrine cytokine tumor impfstoffe |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0869803B1 (de) |
| JP (1) | JP2000502711A (de) |
| AT (1) | ATE237338T1 (de) |
| AU (1) | AU1355697A (de) |
| DE (1) | DE69627527T2 (de) |
| ES (1) | ES2191784T3 (de) |
| WO (1) | WO1997024132A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9620350D0 (en) | 1996-09-30 | 1996-11-13 | Maudsley David J | Cancer vaccine |
| EP0893507A1 (de) | 1997-07-25 | 1999-01-27 | Institut Gustave Roussy | Verwendung von MHC Klass II Liganden (CD4 und LAG-3) als Adjuvanz für Impfungen und von LAG-3 in der Behandlung von Krebs |
| DE19832840C1 (de) * | 1998-07-21 | 2000-06-08 | Kerkmann Tucek Aida | Mittel zur Immuntherapie von Tumorerkrankungen |
| GB9827103D0 (en) | 1998-12-10 | 1999-02-03 | Onyvax Ltd | New cancer treatments |
| GB9827104D0 (en) * | 1998-12-10 | 1999-02-03 | Onyvax Ltd | New cancer treatments |
| GB9911823D0 (en) * | 1999-05-21 | 1999-07-21 | Onyvax Ltd | New vaccine formulations |
| CA2374294A1 (en) * | 1999-05-21 | 2000-11-30 | Onyvax Limited | New vaccine formulations - 2 |
| WO2000071156A2 (en) * | 1999-05-21 | 2000-11-30 | Onyvax Limited | New vaccine formulations-3 |
| WO2001075073A2 (en) | 2000-04-01 | 2001-10-11 | Onyvax Limited | Prostate cell lines and their use |
| EP1441758A2 (de) * | 2001-11-09 | 2004-08-04 | MediGene Aktiengesellschaft | Allogene vakzine enthaltend eine ein costimulatorisches polypeptid exprimierende tumorzelle |
| US20090110702A1 (en) | 2002-07-12 | 2009-04-30 | The Johns Hopkins University | Mesothelin Vaccines and Model Systems and Control of Tumors |
| WO2004006837A2 (en) | 2002-07-12 | 2004-01-22 | The Johns Hopkins University | Mesothelin vaccines and model systems |
| US9200036B2 (en) | 2002-07-12 | 2015-12-01 | The Johns Hopkins University | Mesothelin vaccines and model systems |
| US7176022B2 (en) | 2002-12-20 | 2007-02-13 | Cell Genesys, Inc. | Directly injectable formulations which provide enhanced cryoprotection of cell products |
| US20050019336A1 (en) | 2003-07-23 | 2005-01-27 | Dalgleish Angus George | Human prostate cell lines in cancer treatment |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2002025A1 (en) * | 1988-11-02 | 1990-05-02 | Geary W. Collins | Continuous mammalian cell lines having monocyte-macrophage characteristics and their establishment in vitro |
| ES2080341T3 (es) * | 1990-09-14 | 1996-02-01 | Univ Johns Hopkins | Metodos y composiciones para la terapia genetica y la potenciacion de la inmunidad antitumoral. |
| WO1994004196A1 (en) * | 1992-08-14 | 1994-03-03 | Imperial Cancer Research Technology Limited | Tumour therapy |
-
1996
- 1996-12-26 EP EP96945109A patent/EP0869803B1/de not_active Expired - Lifetime
- 1996-12-26 DE DE69627527T patent/DE69627527T2/de not_active Expired - Lifetime
- 1996-12-26 WO PCT/US1996/020802 patent/WO1997024132A1/en not_active Ceased
- 1996-12-26 JP JP09524574A patent/JP2000502711A/ja active Pending
- 1996-12-26 AT AT96945109T patent/ATE237338T1/de not_active IP Right Cessation
- 1996-12-26 ES ES96945109T patent/ES2191784T3/es not_active Expired - Lifetime
- 1996-12-26 AU AU13556/97A patent/AU1355697A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0869803A1 (de) | 1998-10-14 |
| AU1355697A (en) | 1997-07-28 |
| DE69627527D1 (en) | 2003-05-22 |
| EP0869803B1 (de) | 2003-04-16 |
| DE69627527T2 (de) | 2004-03-04 |
| WO1997024132A1 (en) | 1997-07-10 |
| ES2191784T3 (es) | 2003-09-16 |
| JP2000502711A (ja) | 2000-03-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE237338T1 (de) | Allogene parakrine cytokine tumor impfstoffe | |
| ATE505206T1 (de) | Verwendung des melanomdifferenzierungs assoziierten gens (mda-7) zur umwandlung eines krebsphänotyps | |
| FI935174A0 (fi) | Tumoeravstoetande antigenprekursorer, tumoeravstoetande antigener och anvaendning av dem | |
| DK0873332T3 (da) | Discodermolidforbindelser samt farmaceutiske sammensætninger indeholdende dem til cancerterapi | |
| ATE420192T1 (de) | Verfahren zur verringerung der antigenität des adeno-assoziierten virus strukturproteins | |
| BR8301918A (pt) | Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase | |
| FI943750A0 (fi) | Menetelmä nekroositekijän valmistamiseksi | |
| EA199801031A1 (ru) | Ингибиторы протеинфарнезилтрансферазы | |
| AU1378499A (en) | Methods for treating prostate tumors using radioactive compositions | |
| ES8705521A1 (es) | Un metodo de producir un polipetido similar a factor de necrosis de tumores (tnf) de mamiferos. | |
| DE69521521D1 (de) | Mono- oder polyfunktionelle konjugate von polylysine | |
| HU9501288D0 (en) | Recombinant method and host for manufacture of xylitol | |
| DE3477791D1 (en) | Nucleoside process | |
| DE69332688D1 (de) | Verwendung von modifiziertem c-reaktiven protein zur herstellung eines medikaments zur behandlung von krebs | |
| HUT61202A (en) | Process for producing pharmaceutical compositions neutralizing procoagulant activity caused by tumour cells | |
| EP0325191A3 (en) | Composition and method for protecting against diseases caused by microorganisms | |
| ATE38036T1 (de) | Benzothiophenderivate als bronchodilatoren. | |
| WO1997014712A3 (de) | Sulfamat-derivate von 1,3,5(10)-estratrien-derivaten, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen | |
| BG101038A (bg) | Супресия на растежа на туморни клетки посредствомсиндекан- 1 ектоучастък | |
| AU6319480A (en) | 2-hydroxyalkyl-3,4,5-trihydroxypiperidines | |
| EA200000522A1 (ru) | 5-htагонисты | |
| ATE449172T1 (de) | Säugetiergene, die an der viralen infektion beteiligt sind | |
| KR950700684A (ko) | 시클릭 항-종양 촉진제 화합물, 그의 조성물, 제조 방법 및 용도(Cyclic Anti-Tumor Promoter Compounds, Compositions and Methods for Production and Use) | |
| EP0255717A3 (de) | Gangliosid-Derivate und Verfahren zur Herstellung davon | |
| AU3300797A (en) | Selenophene anti-tumor agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |