ATE235506T1 - Behandlung einer proteinlösung mit a1/fe und anschliesende membrankonzentration - Google Patents

Behandlung einer proteinlösung mit a1/fe und anschliesende membrankonzentration

Info

Publication number
ATE235506T1
ATE235506T1 AT96917365T AT96917365T ATE235506T1 AT E235506 T1 ATE235506 T1 AT E235506T1 AT 96917365 T AT96917365 T AT 96917365T AT 96917365 T AT96917365 T AT 96917365T AT E235506 T1 ATE235506 T1 AT E235506T1
Authority
AT
Austria
Prior art keywords
protein solution
treatment
membrane concentration
following membrane
protein
Prior art date
Application number
AT96917365T
Other languages
German (de)
English (en)
Inventor
Torben Nielsen
Mads Aage Laustsen
Niels-Viktor Nielsen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE235506T1 publication Critical patent/ATE235506T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96917365T 1995-06-02 1996-05-31 Behandlung einer proteinlösung mit a1/fe und anschliesende membrankonzentration ATE235506T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK62695 1995-06-02
PCT/DK1996/000229 WO1996038469A1 (en) 1995-06-02 1996-05-31 Al/Fe-TREATMENT OF A PROTEIN SOLUTION, FOLLOWED BY MEMBRANE CONCENTRATION

Publications (1)

Publication Number Publication Date
ATE235506T1 true ATE235506T1 (de) 2003-04-15

Family

ID=8095720

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96917365T ATE235506T1 (de) 1995-06-02 1996-05-31 Behandlung einer proteinlösung mit a1/fe und anschliesende membrankonzentration

Country Status (9)

Country Link
EP (1) EP0828753B1 (oth)
JP (1) JPH11511118A (oth)
CN (1) CN1114613C (oth)
AT (1) ATE235506T1 (oth)
AU (1) AU5996996A (oth)
DE (1) DE69626976T2 (oth)
DK (1) DK0828753T3 (oth)
IN (1) IN181859B (oth)
WO (1) WO1996038469A1 (oth)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2810667B1 (fr) * 2000-06-23 2004-09-03 Warner Lambert Co Procede d'isolement et de purification d'une proteine, et proteine obtenue
JP2004533219A (ja) 2001-02-21 2004-11-04 ディヴァーサ コーポレイション αアミラーゼ活性を有する酵素及びその使用方法
US7659102B2 (en) 2001-02-21 2010-02-09 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
WO2002092802A1 (en) * 2001-05-14 2002-11-21 Diversa Corporation Novel methods of enzyme purification
JP5562510B2 (ja) 2001-06-28 2014-07-30 ノヴォ ノルディスク アー／エス 修飾ｇｌｐ−１の安定な処方剤
US7118891B2 (en) 2001-12-11 2006-10-10 Novozymes A/S Crystal harvest from fermentation broth
CN100487114C (zh) * 2001-12-11 2009-05-13 诺维信公司 从发酵液收获晶体
WO2004091544A2 (en) 2003-03-06 2004-10-28 Diversa Corporation Amylases, nucleic acids encoding them and methods for making and using them
JP2007524592A (ja) 2003-06-03 2007-08-30 ノボ・ノルデイスク・エー／エス 安定化された薬学的ペプチド組成物
ATE541582T1 (de) 2003-06-03 2012-02-15 Novo Nordisk As Stabilisierte pharmazeutische glp-1 peptid zusammensetzungen
CN1882356B (zh) 2003-11-20 2015-02-25 诺沃挪第克公司 对于生产和用于注射装置中是最佳的含有丙二醇的肽制剂
JP4965446B2 (ja) 2004-08-31 2012-07-04 ノヴォ ノルディスク アー／エス ペプチド、ポリペプチド及びタンパク質の安定化のためのトリス（ヒドロキシメチル）アミノメタンの使用
BRPI0517341A (pt) 2004-11-12 2008-10-07 Novo Nordisk As composição farmacêutica estável em prateleira, métodos para a preparação de uma composição farmacêutica, para o tratamento de hiperglicemia, para o tratamento de obesidade, deficiência de célula beta, igt ou dislipidemia, para a preparação de uma solução estável de um composto glp-1, para a preparação de um composto glp-1 estável e para a preparação de uma composição farmacêutica estável em prateleira de um composto glp-1, solução estável de um composto glp-1, e, uso de uma solução estável de um composto glp-1
AU2006292739A1 (en) 2005-09-15 2007-03-29 Wyeth Protein floculation using salts
DK2069490T4 (en) 2006-12-21 2018-04-23 Syngenta Participations Ag Amylases and Glucoamylases, Nucleic Acids Encoding Them, and Methods of Preparation and Use thereof
US20120252066A1 (en) * 2011-03-29 2012-10-04 Heng Meng H Methods of foam control
WO2014068083A1 (en) 2012-11-01 2014-05-08 Novozymes A/S Method for removal of dna
DK3071589T3 (en) 2013-11-19 2018-06-14 Kemira Oyj METHOD OF REDUCING THE COLOR OF A BIOTECHNOLOGICAL LIQUID
EP4360651A3 (en) 2017-08-24 2024-07-17 Novo Nordisk A/S Glp-1 compositions and uses thereof
CN108949703A (zh) * 2018-06-28 2018-12-07 大连理工大学 一种半纤维小体类似物粗提纯方法
MX2021015364A (es) 2019-06-13 2022-01-24 Basf Se Metodo de recuperacion de una proteina de un caldo de fermentacion mediante el uso de un cation divalente.
TWI878456B (zh) 2020-02-18 2025-04-01 丹麥商諾佛 儂迪克股份有限公司 Glp-1組成物及其用途
US20230331775A1 (en) 2020-09-22 2023-10-19 Basf Se Method for recovering a protein from a fermentation broth comprising a high degree of lysed cells
CN112500471B (zh) * 2020-12-22 2022-09-27 中美华世通生物医药科技(武汉)股份有限公司 一种制备高澄清度蛋白琥珀酸铁的方法
EP4565710A1 (en) 2022-08-02 2025-06-11 Basf Se Stabilized protein production process using bacillus host cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795586A (en) * 1969-08-11 1974-03-05 Pabst Brewing Co Recovery of enzymes
KR880009044A (ko) * 1987-01-30 1988-09-13 원본미기재 묽은 수용액으로부터 소마토트로핀의 회수방법
US4894444A (en) * 1987-07-16 1990-01-16 Merck & Co., Inc. Recovery and purification of immunogens from immunogen-alum complexes
DE3915277A1 (de) * 1989-05-10 1990-11-15 Henkel Kgaa Verfahren zur reinigung von enzymfluessigkonzentraten
DE4037530A1 (de) * 1990-11-26 1992-05-27 Henkel Kgaa Faellungsverfahren fuer exocellulaere proteine
DK91092D0 (oth) * 1992-07-10 1992-07-10 Novo Nordisk As

Also Published As

Publication number Publication date
DE69626976T2 (de) 2004-03-04
CN1114613C (zh) 2003-07-16
DK0828753T3 (da) 2003-06-30
EP0828753B1 (en) 2003-03-26
JPH11511118A (ja) 1999-09-28
EP0828753A1 (en) 1998-03-18
IN181859B (oth) 1998-10-03
WO1996038469A1 (en) 1996-12-05
CN1186498A (zh) 1998-07-01
AU5996996A (en) 1996-12-18
DE69626976D1 (de) 2003-04-30

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