ATE232722T1 - Cyclosporin biologisch abbaubare mikro- und nanosphären mit gesteuerter freisetzung - Google Patents

Cyclosporin biologisch abbaubare mikro- und nanosphären mit gesteuerter freisetzung

Info

Publication number
ATE232722T1
ATE232722T1 AT96909319T AT96909319T ATE232722T1 AT E232722 T1 ATE232722 T1 AT E232722T1 AT 96909319 T AT96909319 T AT 96909319T AT 96909319 T AT96909319 T AT 96909319T AT E232722 T1 ATE232722 T1 AT E232722T1
Authority
AT
Austria
Prior art keywords
cyclosporin
lactide
poly
nanospheres
formulation
Prior art date
Application number
AT96909319T
Other languages
English (en)
Inventor
Zebunnissa Ramtoola
Original Assignee
Elan Corp Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp Plc filed Critical Elan Corp Plc
Application granted granted Critical
Publication of ATE232722T1 publication Critical patent/ATE232722T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/795—Composed of biological material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/931—Medical device coating
AT96909319T 1995-04-03 1996-04-02 Cyclosporin biologisch abbaubare mikro- und nanosphären mit gesteuerter freisetzung ATE232722T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE950233A IE75744B1 (en) 1995-04-03 1995-04-03 Controlled release biodegradable micro- and nanospheres containing cyclosporin
PCT/IE1996/000017 WO1996031202A1 (en) 1995-04-03 1996-04-02 Controlled release biodegradable micro- and nanospheres containing cyclosporin

Publications (1)

Publication Number Publication Date
ATE232722T1 true ATE232722T1 (de) 2003-03-15

Family

ID=11040700

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96909319T ATE232722T1 (de) 1995-04-03 1996-04-02 Cyclosporin biologisch abbaubare mikro- und nanosphären mit gesteuerter freisetzung

Country Status (14)

Country Link
US (1) US5641745A (de)
EP (1) EP0818996B1 (de)
JP (1) JP3875721B2 (de)
AT (1) ATE232722T1 (de)
AU (1) AU700612B2 (de)
CA (1) CA2217462C (de)
DE (1) DE69626278T2 (de)
DK (1) DK0818996T3 (de)
ES (1) ES2189868T3 (de)
IE (1) IE75744B1 (de)
NZ (1) NZ304975A (de)
PT (1) PT818996E (de)
WO (1) WO1996031202A1 (de)
ZA (1) ZA962670B (de)

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Also Published As

Publication number Publication date
CA2217462A1 (en) 1996-10-10
WO1996031202A1 (en) 1996-10-10
IE950233A1 (en) 1996-10-16
ZA962670B (en) 1996-10-09
EP0818996B1 (de) 2003-02-19
AU5286696A (en) 1996-10-23
PT818996E (pt) 2003-06-30
EP0818996A1 (de) 1998-01-21
DE69626278T2 (de) 2003-07-24
JP3875721B2 (ja) 2007-01-31
JPH11503147A (ja) 1999-03-23
IE75744B1 (en) 1997-09-24
DK0818996T3 (da) 2003-06-10
ES2189868T3 (es) 2003-07-16
CA2217462C (en) 2010-08-03
US5641745A (en) 1997-06-24
DE69626278D1 (de) 2003-03-27
AU700612B2 (en) 1999-01-07
NZ304975A (en) 1998-09-24

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