ATE227341T1 - Trimerisierende polypeptide, deren herstellung und verwendung - Google Patents
Trimerisierende polypeptide, deren herstellung und verwendungInfo
- Publication number
- ATE227341T1 ATE227341T1 AT95918689T AT95918689T ATE227341T1 AT E227341 T1 ATE227341 T1 AT E227341T1 AT 95918689 T AT95918689 T AT 95918689T AT 95918689 T AT95918689 T AT 95918689T AT E227341 T1 ATE227341 T1 AT E227341T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- amino acid
- amino acids
- preparation
- heterotrimerization
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 102000004405 Collectins Human genes 0.000 abstract 1
- 108090000909 Collectins Proteins 0.000 abstract 1
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000010899 nucleation Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- 108020001580 protein domains Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4726—Lectins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9409768A GB9409768D0 (en) | 1994-05-16 | 1994-05-16 | Trimerising polypeptides |
| PCT/GB1995/001104 WO1995031540A1 (en) | 1994-05-16 | 1995-05-16 | Trimerising polypeptides, their manufacture and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE227341T1 true ATE227341T1 (de) | 2002-11-15 |
Family
ID=10755201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95918689T ATE227341T1 (de) | 1994-05-16 | 1995-05-16 | Trimerisierende polypeptide, deren herstellung und verwendung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6190886B1 (de) |
| EP (1) | EP0757720B1 (de) |
| JP (2) | JPH10500298A (de) |
| AT (1) | ATE227341T1 (de) |
| AU (1) | AU2451995A (de) |
| CA (1) | CA2190264A1 (de) |
| DE (1) | DE69528761T2 (de) |
| DK (1) | DK0757720T3 (de) |
| ES (1) | ES2186718T3 (de) |
| GB (1) | GB9409768D0 (de) |
| PT (1) | PT757720E (de) |
| WO (1) | WO1995031540A1 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO591797A0 (en) | 1997-03-27 | 1997-04-24 | Commonwealth Scientific And Industrial Research Organisation | High avidity polyvalent and polyspecific reagents |
| EP0938571B8 (de) * | 1996-10-28 | 2008-07-02 | University of Lausanne | Verfahren zur oligomerisation von peptiden |
| WO1998018918A1 (en) * | 1996-10-29 | 1998-05-07 | Commonwealth Scientific And Industrial Research Organisation | Stable expression of triple helical proteins |
| AU736707B2 (en) | 1997-06-11 | 2001-08-02 | Anaphore, Inc. | Trimerising module |
| US7914814B2 (en) * | 1997-09-17 | 2011-03-29 | Strategic Science & Technologies, Llc | Topical delivery of arginine of cause beneficial effects |
| CA2313028A1 (en) * | 1997-12-01 | 1999-06-10 | Cfy Biomedicals, Inc. | Multivalent recombinant antibodies for treating hrv infections |
| US20030035798A1 (en) * | 2000-08-16 | 2003-02-20 | Fang Fang | Humanized antibodies |
| US7300774B1 (en) * | 1999-12-09 | 2007-11-27 | The Regents Of The University Of California | Multimeric fusion proteins of the TNF superfamily ligands |
| EP1179013A1 (de) * | 1999-05-14 | 2002-02-13 | Medical Research Council | Proteingerüst und seine verwendung zur multimerisierung von monomeren peptiden |
| EP2343317A1 (de) | 2000-11-10 | 2011-07-13 | F. Hoffmann-La Roche Ltd. | Apolipoprotein-konstrukte |
| CA2440235A1 (en) * | 2001-03-06 | 2002-09-12 | Mustapha Abdelouahed | Carrier chimeric proteins, targeted carrier chimeric proteins and preparation thereof |
| US20030138440A1 (en) | 2001-07-19 | 2003-07-24 | Fang Fang | Multimeric proteins and methods of making and using same |
| EP1440083B1 (de) | 2001-10-25 | 2013-01-02 | Medical Research Council | Moleküle |
| JP4660092B2 (ja) * | 2001-12-21 | 2011-03-30 | イミユネツクス・コーポレイシヨン | 組換えポリペプチド |
| EP2311867A1 (de) | 2002-10-29 | 2011-04-20 | Anaphore, Inc. | Trimeres Bindungsprotein für trimeres Zytokin |
| WO2005037852A2 (en) * | 2003-08-22 | 2005-04-28 | Barnes-Jewish Hospital | Trimerizing polypeptides and their uses |
| US7268116B2 (en) * | 2003-10-02 | 2007-09-11 | Genhunter Corp. | Methods and compositions for producing secreted trimeric receptor analogs and biologically active fusion proteins |
| US8030448B2 (en) | 2004-02-16 | 2011-10-04 | Techno Network Shikoku Co., Ltd. | Polypeptide having collagen-like structure |
| JP2008520214A (ja) | 2004-11-22 | 2008-06-19 | ボレアン・ファルマ・アンパルトセルスカブ | Ｔｎｆアンタゴニスト |
| US7655439B2 (en) * | 2005-09-09 | 2010-02-02 | Zymogenetics, Inc. | Trimerizing polypeptides |
| US20070264687A1 (en) * | 2005-12-15 | 2007-11-15 | Min-Yuan Chou | Recombinant triplex scaffold-based polypeptides |
| US10183986B2 (en) * | 2005-12-15 | 2019-01-22 | Industrial Technology Research Institute | Trimeric collagen scaffold antibodies |
| EP2674440B1 (de) | 2005-12-16 | 2019-07-03 | IBC Pharmaceuticals, Inc. | Polyvalente bioaktive anordnungen auf immunglobulinbasis |
| CN103159857B (zh) * | 2007-05-21 | 2014-11-05 | 财团法人工业技术研究院 | 以重组的三股螺旋支架为基础的复合物 |
| ES2567704T3 (es) | 2007-07-10 | 2016-04-26 | Apogenix Gmbh | Proteínas de fusión de colectina de la superfamilia de TNF |
| WO2009058285A2 (en) | 2007-10-29 | 2009-05-07 | Virginia Tech Intellectual Properties, Inc. | PORCINE DC-SIGN, ICAM-3 AND LSECtin AND USES THEREOF |
| EP2294202B1 (de) | 2008-07-08 | 2015-05-20 | Medicago Inc. | Lösliche rekombinante influenza-antigene |
| JP2012504969A (ja) | 2008-10-10 | 2012-03-01 | アナフォア インコーポレイテッド | Ｔｒａｉｌ−ｒ１及びｔｒａｉｌ−ｒ２に結合するポリペプチド |
| DK2380979T3 (da) * | 2008-12-22 | 2015-06-22 | Univ Hokkaido Nat Univ Corp | Proteinstof med trippelhelixstruktur samt fremgangsmåde til dets fremstilling |
| EP2829550B1 (de) | 2009-01-09 | 2016-11-16 | Apogenix AG | Trimer-bildende Fusionsproteine |
| WO2010122181A1 (es) * | 2009-04-20 | 2010-10-28 | Universidad Autónoma de Madrid | Proteínas oligoméricas y sus aplicaciones |
| US20110086806A1 (en) * | 2009-10-09 | 2011-04-14 | Anaphore, Inc. | Polypeptides that Bind IL-23R |
| JP2013507124A (ja) * | 2009-10-09 | 2013-03-04 | アナフォア インコーポレイテッド | Ｉｌ−２３ｒを結合するポリペプチド |
| AU2014233114B2 (en) | 2013-03-15 | 2018-03-08 | Richard S. Kornbluth | Composition comprised of antigen linked to a TNF SuperFamily ligand |
| JP2014218510A (ja) * | 2014-08-11 | 2014-11-20 | アポゲニクスゲゼルシャフト ミット ベシュレンクテルハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ | 三量体形成融合タンパク質 |
| CN108431027B (zh) | 2015-11-13 | 2022-07-22 | 思百博技术股份公司 | 电荷逆转的n端蜘蛛丝蛋白结构域及其用途 |
| GB201522610D0 (en) * | 2015-12-22 | 2016-02-03 | Univ Southampton | Protein |
| JP2016210791A (ja) * | 2016-08-03 | 2016-12-15 | アポゲニクス アーゲー | 三量体形成融合タンパク質 |
| US11377490B2 (en) | 2017-05-31 | 2022-07-05 | Sichuan Clover Biopharmaceuticals, Inc | Method for treating cancer using disulfide-linked trimeric 4-1BBL |
| WO2021249116A1 (en) | 2020-06-10 | 2021-12-16 | Sichuan Clover Biopharmaceuticals, Inc. | Coronavirus vaccine compositions, methods, and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716805A (en) * | 1991-10-25 | 1998-02-10 | Immunex Corporation | Methods of preparing soluble, oligomeric proteins |
-
1994
- 1994-05-16 GB GB9409768A patent/GB9409768D0/en active Pending
-
1995
- 1995-05-16 EP EP95918689A patent/EP0757720B1/de not_active Expired - Lifetime
- 1995-05-16 AU AU24519/95A patent/AU2451995A/en not_active Abandoned
- 1995-05-16 WO PCT/GB1995/001104 patent/WO1995031540A1/en active IP Right Grant
- 1995-05-16 ES ES95918689T patent/ES2186718T3/es not_active Expired - Lifetime
- 1995-05-16 DE DE69528761T patent/DE69528761T2/de not_active Expired - Lifetime
- 1995-05-16 AT AT95918689T patent/ATE227341T1/de not_active IP Right Cessation
- 1995-05-16 CA CA002190264A patent/CA2190264A1/en not_active Abandoned
- 1995-05-16 DK DK95918689T patent/DK0757720T3/da active
- 1995-05-16 JP JP7529462A patent/JPH10500298A/ja not_active Withdrawn
- 1995-05-16 US US08/737,629 patent/US6190886B1/en not_active Expired - Lifetime
- 1995-05-16 PT PT95918689T patent/PT757720E/pt unknown
-
2005
- 2005-08-09 JP JP2005230930A patent/JP3836865B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2451995A (en) | 1995-12-05 |
| JP2005328851A (ja) | 2005-12-02 |
| DE69528761T2 (de) | 2003-07-17 |
| ES2186718T3 (es) | 2003-05-16 |
| GB9409768D0 (en) | 1994-07-06 |
| US6190886B1 (en) | 2001-02-20 |
| JP3836865B2 (ja) | 2006-10-25 |
| DE69528761D1 (de) | 2002-12-12 |
| PT757720E (pt) | 2003-03-31 |
| JPH10500298A (ja) | 1998-01-13 |
| DK0757720T3 (da) | 2003-03-17 |
| EP0757720B1 (de) | 2002-11-06 |
| CA2190264A1 (en) | 1995-11-23 |
| WO1995031540A1 (en) | 1995-11-23 |
| EP0757720A1 (de) | 1997-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0757720 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |