ATE224885T1 - Chromanon und thiochromanon derivate - Google Patents

Chromanon und thiochromanon derivate

Info

Publication number
ATE224885T1
ATE224885T1 AT99917963T AT99917963T ATE224885T1 AT E224885 T1 ATE224885 T1 AT E224885T1 AT 99917963 T AT99917963 T AT 99917963T AT 99917963 T AT99917963 T AT 99917963T AT E224885 T1 ATE224885 T1 AT E224885T1
Authority
AT
Austria
Prior art keywords
chromanone
thiochromanone
derivatives
thiochromanone derivatives
Prior art date
Application number
AT99917963T
Other languages
English (en)
Inventor
Andreas Billich
Peter Nussbaumer
Erwin Schreiner
Ingeborg Schuster
Original Assignee
Novartis Ag
Novartis Erfind Verwalt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Novartis Erfind Verwalt Gmbh filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE224885T1 publication Critical patent/ATE224885T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
AT99917963T 1998-04-09 1999-04-07 Chromanon und thiochromanon derivate ATE224885T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9807779.5A GB9807779D0 (en) 1998-04-09 1998-04-09 Organic compounds
PCT/EP1999/002349 WO1999052890A1 (en) 1998-04-09 1999-04-07 Chromanone and thiochromanone derivatives

Publications (1)

Publication Number Publication Date
ATE224885T1 true ATE224885T1 (de) 2002-10-15

Family

ID=10830229

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99917963T ATE224885T1 (de) 1998-04-09 1999-04-07 Chromanon und thiochromanon derivate

Country Status (16)

Country Link
US (1) US6346626B1 (de)
EP (1) EP1070059B1 (de)
JP (1) JP3425424B2 (de)
AR (1) AR018178A1 (de)
AT (1) ATE224885T1 (de)
AU (1) AU3605499A (de)
CO (1) CO5031242A1 (de)
DE (1) DE69903143T2 (de)
DK (1) DK1070059T3 (de)
ES (1) ES2184439T3 (de)
GB (1) GB9807779D0 (de)
MY (1) MY118897A (de)
PE (1) PE20000419A1 (de)
PT (1) PT1070059E (de)
TW (1) TW513420B (de)
WO (1) WO1999052890A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5261573A1 (es) 1999-11-19 2003-03-31 Novartis Ag Derivados de benzoxa y bezotiazol, compuesto y composicion farmaceutica que los contiene y proceso para la preparacion de la mencionada composicion
JP2002020362A (ja) * 2000-07-06 2002-01-23 Nippon Oruganon Kk 新規ビフェニル誘導体
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
GB0127923D0 (en) * 2001-11-21 2002-01-16 Sterix Ltd Compound
US6924376B2 (en) 2002-04-17 2005-08-02 Cytokinetics, Inc. Compounds, compositions and methods
US20060051343A1 (en) * 2002-06-19 2006-03-09 Tatsuya Watanabe Preventives remedies for bone and joint diseases
ATE423110T1 (de) 2002-07-17 2009-03-15 Cytokinetics Inc Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen
DE10260955A1 (de) * 2002-12-20 2004-07-08 Henkel Kgaa Verwendung von Steroidsulfatase-Inhibitoren zur Verminderung von Haarausfall
TW200524588A (en) * 2003-09-22 2005-08-01 Nippon Shinyaku Co Ltd Hair restorer
WO2005058842A1 (en) 2003-12-15 2005-06-30 Laboratoire Theramex 1-n-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them
GB0411562D0 (en) 2004-05-24 2004-06-23 Sterix Ltd Compound
GB0412492D0 (en) 2004-06-04 2004-07-07 Sterix Ltd Compound
GB0505541D0 (en) * 2005-03-17 2005-04-27 Novartis Ag Organic compounds
GB0513702D0 (en) 2005-07-04 2005-08-10 Sterix Ltd Compound
GB0604142D0 (en) 2006-03-01 2006-04-12 Sterix Ltd Compound
GB0706072D0 (en) 2007-03-28 2007-05-09 Sterix Ltd Compound
KR20100068287A (ko) 2007-09-17 2010-06-22 쁘레글렘 에스.아. 폐경기 전 여성의 에스트로겐 의존성 질환의 치료
GB0722779D0 (en) 2007-11-20 2008-01-02 Sterix Ltd Compound
GB0914767D0 (en) 2009-08-24 2009-09-30 Sterix Ltd Compound
CN107648216B (zh) * 2010-07-27 2021-03-30 波士顿大学管理委员会 作为新型癌症疗法的芳烃受体(AhR)调节剂
EP3260445A1 (de) * 2016-06-24 2017-12-27 Universität Konstanz Verbindungen zur verwendung als antibakterielles oder fungizides mittel und als zinksensor
EP3502095A1 (de) 2017-12-22 2019-06-26 Universität Konstanz Verbindung zur verwendung gegen pathogene neisseria- und haemophilus-spezies und moraxella catarrhalis

Family Cites Families (21)

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CH619701A5 (de) * 1975-08-07 1980-10-15 Bayer Ag
US4060619A (en) * 1976-01-14 1977-11-29 Ayerst Mckenna And Harrison Ltd. 1,4-Dihydro-4-oxo-benzothiopyrano (4,3-b)pyridine-2-carboxylates and derivatives
DE3243158A1 (de) 1982-11-23 1984-05-24 Basf Ag, 6700 Ludwigshafen Neue sulfonsaeureester von hydroxycumarinen, ihre herstellung und sie enthaltende arzneimittel
FR2543140B1 (fr) 1983-03-24 1985-06-21 Cortial Nouveaux acides flavone-carboxyliques-4', leur methode de preparation et leur application en therapeutique
IN164232B (de) * 1986-04-11 1989-02-04 Hoechst India
GB8800199D0 (en) 1988-01-06 1988-02-10 Beecham Group Plc Pharmaceutical preparation
US5194446A (en) 1989-06-12 1993-03-16 A. H. Robins Company, Incorporated Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals
US5273993A (en) 1989-06-12 1993-12-28 A. H. Robins Company, Incorporated Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals
PT94305B (pt) 1989-06-12 1997-02-28 Robins Co Inc A H Processo para a preparacao de compostos tendo um ou mais radicais aminossulfoniloxi uteis como produtos farmaceuticos
US5025031A (en) 1989-11-30 1991-06-18 A. H. Robins Co., Inc. Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants
GB9118478D0 (en) 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
WO1997032872A1 (en) * 1996-03-05 1997-09-12 Imperial College Of Science Technology And Medicine Compounds with a sulfamate group
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
DE4308451A1 (de) 1992-09-10 1994-04-14 Bayer Ag 3-Aryl-pyron-Derivate
US6013642A (en) 1994-04-05 2000-01-11 Foulkes; Roland Use of estrone derivatives as steroid sulphatase inhibitors
US5556847A (en) 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
US5567831A (en) 1995-08-16 1996-10-22 Duguesne University Of The Holy Ghost Non-steroidal sulfatase inhibitor compounds and their method of use
DE19532311A1 (de) 1995-09-01 1997-03-06 Basf Ag Benzoylderivate
AU3867997A (en) * 1996-08-27 1998-03-19 Shionogi & Co., Ltd. Chromene-3-carboxylate derivatives
US5763492A (en) 1996-10-01 1998-06-09 Duguesne University Of The Holy Ghost Methods for effecting memory enhancement mediated by non-steroidal sulfatase inhibitors
US6028088A (en) * 1998-10-30 2000-02-22 The University Of Mississippi Flavonoid derivatives

Also Published As

Publication number Publication date
JP2002511459A (ja) 2002-04-16
US6346626B1 (en) 2002-02-12
AU3605499A (en) 1999-11-01
DE69903143T2 (de) 2003-06-05
PT1070059E (pt) 2003-01-31
PE20000419A1 (es) 2000-05-29
CO5031242A1 (es) 2001-04-27
MY118897A (en) 2005-02-28
ES2184439T3 (es) 2003-04-01
TW513420B (en) 2002-12-11
AR018178A1 (es) 2001-10-31
EP1070059A1 (de) 2001-01-24
DK1070059T3 (da) 2002-12-16
EP1070059B1 (de) 2002-09-25
WO1999052890A1 (en) 1999-10-21
JP3425424B2 (ja) 2003-07-14
GB9807779D0 (en) 1998-06-10
DE69903143D1 (de) 2002-10-31

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